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Popular Abstract in Swedish Ett felaktigt protein som klumpar ihop sig i hjärnans blodkärl är orsaken till hjärnblödning och för tidig död hos unga islänningar. Sjukdomen är ärftlig och uppkommer på grund av en enda felaktig byggsten, orsakad av en mutation, i proteinet cystatin C. Det muterade proteinet bildar mikroskopiska proteinkedjor, fibriller, som klumpar ihop sig i bland annat hjärnans bloThe pathophysiological process in Alzheimer’s disease and other amyloid disorders usually involves the transformation of a soluble monomeric protein via potentially toxic oligomers into amyloid fibrils. The structure and properties of the intermediary oligomers have been difficult to study due to their instability and dynamic equilibrium with smaller and larger species. This has hampered the devel

In order to explore verbal-nonverbal integration, we investigated the influence of cognitive and linguistic ability on gaze behavior during spoken language conversation between children with mild-to-moderate hearing impairment (HI) and normal-hearing (NH) peers. Ten HI-NH and 10 NH-NH dyads performed a referential communication task requiring description of faces. During task performance, eye move

Systems based on bag-of-words models from image features collected at maxima of sparse interest point operators have been used successfully for both computer visual object and action recognition tasks. While the sparse, interest-point based approach to recognition is not inconsistent with visual processing in biological systems that operate in 'saccade and fixate' regimes, the methodology and emph

The purpose of this study is to describe and analyse changes in the pledge element of the ordination in the Church of Sweden. The transition in 1893 from a clerical oath to an affirmation will be particularly in focus and its causes and effects identified. My intention is thus to contribute to the history of the Swedish clerical oath, describing its complexity and multifarious range of meaning. In

This paper presents two circuits, a complete 1.5 V 28 GHz SiGe beam steering PLL and a standalone 28 GHz QVCO with I/Q phase imbalance detection and compensation. The circuits were designed in a SiGe process with f T = 200 GHz. The PLL is intended to be used for beam steering in an 81–86 GHz E-band transmitter. Phase control is implemented by DC current injection at the output of a Gilbert archite

Many fish depend primarily on their tail beat for propulsion. Such a tail is commonly modeled as a two-dimensional flapping foil. Here we demonstrate a novel experimental setup of such a foil that heaves and pitches in a soap film. The vortical flow field generated by the foil correlates with thickness variations in the soap film, which appear as interference fringes when the film is illuminated w

1. Quantitative reconstruction of past vegetation distribution and abundance from sedimentary pollen records provides an important baseline for understanding long term ecosystem dynamics and for the calibration of earth system process models such as regional-scale climate models, widely used to predict future environmental change. Most current approaches assume that the amount of pollen produced b

Popular Abstract in Swedish Våra kroppar är uppbyggda av celler. Dessa celler har olika funktioner beroende på var i kroppen de finns. Varje cell tar upp näring, omvandlar den till energi, och energin används för att cellen ska kunna fortleva och utöva specialiserade funktioner samt eventuellt reproducera sig. Kolhydrater är viktiga beståndsdelar i celler. De flesta av oss förknippar kolhydrater Proteoglycans (PGs) is a class of highly anionic macromolecules that consist of one or more linear polysaccharide chains (glycosaminoglycans, GAGs) covalently attached to a core protein. The biological functions of PGs are mainly due to the interactions of GAG chains with various protein ligands and regulatory factors, such as cytokines and growth factors. PGs and GAGs are critical for a diverse s

Popular Abstract in Swedish Att vara kritisk till våra dagars medier är en självklarhet, medan 1800-talets presspionjärer däremot har fått behålla hjältestatusen. I "Pressen i provinsen" tecknas den moderna pressens genombrott dock som en utdragen och långtifrån entydig process. Från att på 1700-talet ha varit arenor där alla hade rätten att delta i det upplysta samtalet, blev tidningarna under böThis study treats ideas of how newspapers should be edited, from the middle of the 18th century to the middle of the 19th century. It deals both with notions of communication and how these were carried out. The empirical focus is on the Swedish province Östergötland and its two main cities, the ecclesiastical, military and administrative Linköping and the mercantile and financially important Norrk

The objectives of this dissertation are 1) to describe what child protection services actually do when assessing risk and deciding on interventions, and 2) to analyze this practice in the light of institutional expectations, organizational demands and professional technology. The field work was carried out in two Danish municipal social service agencies. Data consist of records on families subject

The enzymatic degradation of wood polysaccharides such as cellulose and hemicellulose is an important process in nature. In addition, cellulases and hemicellulases can be used in industrial applications. Fuel ethanol can potentially be produced from wood by enzymatic hydrolysis of cellulose followed by yeast fermentation of the formed sugars. In this thesis, fungal glycoside hydrolases, cellulase

The enzymatic degradation of plant polysaccharides is a process of fundamental importance in nature which involves a wide range of enzymes. In this work, the structure and function of hemicellulose-degrading enzymes was investigated. The focus was on a beta-mannanase (TrMan5A) produced by the filamentous fungus Trichoderma reesei. This enzyme is composed of a catalytic module and a carbohydrate-bi

The field of particle physics is ever evolving. With the recent advent of the Large Hadron Collider (LHC) it is possible that the long sought for Higgs boson is detected. While this is not certain even if it is found it is likely that it will need more precise methods of investigation. For this and other reasons, a new collider called the International Linear Collider (ILC) is being planned. This

While migrating to other countries, persons with disabilities often face additional obstacles as non-nationals and having a disability. Being a vulnerable group it might be hard for them to access remedies and justice. As a light in the darkness, the Convention on the Rights of Persons with Disabilities was adopted in 2006 in order to promote and protect the human rights of persons with disabiliti

Telephone service in Argentina has since its beginning been characterized as one of the most developed in South America. Regarding its development, two distinct periods can be identified. An initial period of private ownership extended from 1878 to 1946. In 1946, when the largest telephone company was bought by the state, a period of predominant state-ownership began that lasted until 1990 when th

Rainflow cycles are often used in fatigue analysis of materials for describing the variability of applied loads. Therefore, an important characteristic of a random load process is the intensity of rainflow cycles, also called the expected rainflow matrix (RFM), which can be used for evaluation of the fatigue life. In this thesis mainly two problems are addressed: the first is computation of the ex

Problem: Today's changing environment gives rise to rapid sequence of events and rapid information dissemination. More attention is given to crisis and how organizations should manage them. Today there is much literature and many approaches to illustrate how an organization can optimize their crisis management, but yet crisis continues to generate problems for organizations. We believe that on

In our time it is widely argued that we are undergoing global transformations that influence the way we think about ourselves and how we interact and form ties with others. The intensified global integration of service sectors during the last five to ten years underscores such transformations. In recent research and among popular commentators the rise of transnational call-centers in India that pr

In the present work the task was to analyse and improve the Automatic Splicing Unit (ASU), which is manufactured for Tetra Pak by Sterners Verkstad. The work includes: • Calculation of the total cost and profitability in the present situation. • Proposal for reducing the manufacturing costs for the ASU. • Suggested improvement for making the assembling more cost efficient. • Proposal for how the p

It is a universally acknowledged truth that the right to strike is one of the fundamentals of labour law. But what is it exactly? To what extent should it be protected and, thus, which limits are permissible?To find a unique answer to those questions is an uneasy task. In the contemporary multilevel legal framework the right to strike is regulated by a variety of provisions, moving from internatio