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Pedal acceleration time (PAT) has recently attracted clinical interest for assessing peripheral arterial disease (PAD), particularly in patients in whom ankle–brachial index (ABI) or toe pressure measurements are unreliable or not feasible, yet its diagnostic worth has not been systematically evaluated. We searched MEDLINE, Embase, ScienceDirect, and the Cochrane Library from inception to January

Hairy cell leukemia (HCL) and HCL variant (HCLv) are distinct, rare, and chronic splenic B-cell lymphomas/leukemias that partially overlap in clinicopathologic presentation but differ in genetic basis, prognosis, and management. HCL is caused by the BRAF-V600E kinase–activating mutation in >95% of the patients, usually has excellent responses to chemotherapy with purine analogues, and is also amen

This article examines Norrköping, Sweden, as a case of industrial transformation through the adaptive reuse of industrial heritage. Once a major center of Swedish manufacturing, Norrköping experienced significant industrial decline during the twentieth century. Rather than treating its former factories and industrial infrastructure solely as remnants of the past, the city has integrated them into

The COVID-19 pandemic led to substantial changes in working conditions in academia. This study aimed to explore how academics’ perceptions of job demands,resources and occupational well-being have changed since the COVID-19 pandemic, as well as their expectations and concerns regarding future working practices. To achieve this aim, we conducted a qualitative follow-up study with 16academics who pa

The international legal framework regulating the problem of human trafficking contains the presumption that the return of victims of human trafficking to their countries of origin is the standard resolution for their cases. However, victims might have legitimate reasons for not wanting to go back. For those victims, resort to the legal framework of the European Convention on Human Rights could be

Background: Nervous system involvement is among the most complex and consequential aspects of systemic lupus erythematosus (SLE). It includes clinically overt neuropsychiatric SLE (NPSLE) manifestations and potentially subclinical involvement. This thesis aimed to increase the understanding of nervous system involvement in SLE through biomarker studies and a population-based epidemiological study.

Directly coupling photovoltaic (PV) arrays to proton exchange membrane (PEM) electrolysers is among the cheapest routes to green hydrogen, but without a power converter the operating point is mismatched to the solar maximum-power point, and that mismatch shifts minute-to-minute with cloud cover. Which coupling strategy maximizes hydrogen yield under realistic solar variability, and whether the ans

This study investigates how the health component of Physical Educationand Health (PEH) is operationalized in Swedish secondary school practice,specifically, how abstract health concepts are negotiated within amovement-based pedagogical tradition. Two research questions guidethe study: (1) How is health content shaped when filtered through thelogic of sport and physical performance? (2) What are th

The European Ecodesign Regulatory Framework has evolved from a primary focus on energy efficiency to broader resource-efficiency and circular economy objectives, with product repairability emerging as a central regulatory priority. While recent Ecodesign measures increasingly incorporate repair-related requirements, there is limited empirical evidence on whether these provisions effectively addres

Artificial intelligence (AI) is reshaping migration, asylum and border policies by enabling automated decision-making. While AI promises efficiency, its use in asylum procedures raises serious human rights concerns, particularly because affected individuals are often in vulnerable positions. The EU AI Act classifies use of AI in asylum procedures as ”high risk”. This report examines whether AI-sup

In response to the massive displacement following the Russian invasion of Ukraine EU Member States decided to activate the Temporary Protection Directive. Although not a new instrument (adopted in 2001) this legal framework to manage large-scale movements, has been activated for the first time in March this year. What are the main characteristics of this Directive? Who can seek protection under th