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Making digital welfare work: conceptualizing digital compensatory work by frontline professionals

Digital technologies in welfare organizations frequently generate gaps, ambiguities, and misalignments that require professional intervention. Yet prior research has tended to portray frontline workers mainly as resistant or adaptive actors, leaving under-examined their active contributions to sustaining broader digital infrastructures. This article introduces the concept of digital compensatory wDigital technologies in welfare organizations frequently generate gaps, ambiguities, andmisalignments that require professional intervention. Yet prior research has tended to portrayfrontline workers mainly as resistant or adaptive actors, leaving under-examined their activecontributions to sustaining broader digital infrastructures. This article introduces the concept ofdigital compensatory work

Decoding of the surfaceome and endocytome in primary glioblastoma cells identifies potential target antigens in the hypoxic tumor niche

Immunotherapies with antibody-drug-conjugates (ADC) and CAR-T cells, targeted at tumor surface antigens (surfaceome), currently revolutionize clinical oncology. However, target identification warrants a better understanding of the surfaceome and how it is modulated by the tumor microenvironment. Here, we decode the surfaceome and endocytome and its remodeling by hypoxic stress in glioblastoma (GBM

Machine learning compared with rule-in/rule-out algorithms and logistic regression to predict acute myocardial infarction based on troponin T concentrations

ObjectiveComputerized decision‐support tools may improve diagnosis of acute myocardial infarction (AMI) among patients presenting with chest pain at the emergency department (ED). The primary aim was to assess the predictive accuracy of machine learning algorithms based on paired high‐sensitivity cardiac troponin T (hs‐cTnT) concentrations with varying sampling times, age, and sex in order to rule

Clinical efficacy of T-cell therapy after short-term BRAF-inhibitor priming in patients with checkpoint inhibitor-resistant metastatic melanoma

PURPOSE: Despite impressive response rates following adoptive transfer of autologous tumor-infiltrating lymphocytes (TILs) in patients with metastatic melanoma, improvement is needed to increase the efficacy and broaden the applicability of this treatment. We evaluated the use of vemurafenib, a small-molecule BRAF inhibitor with immunomodulatory properties, as priming before TIL harvest and adopti

Return to work still possible after several years as a disability pensioner due to musculoskeletal disorders : A population-based study after a new legislation in Sweden permitting “Resting disability pension”

Different strategies have been used to stimulate a return to work (RTW) among individuals suffering from long-term ailments. In Sweden a new law on "resting disability pension" permits disability pensioners to go back to work without jeopardising their benefits. In this study different variables related to RTW during 2000 by means of this legislation were identified among disability pensioners witDifferent strategies have been used to stimulate a return to work (RTW) among individuals suffering from long-term ailments. In Sweden a new law on "resting disability pension" permits disability pensioners to go back to work without jeopardising their benefits. In this study different variables related to RTW during 2000 by means of this legislation were identified among disability pensioners wit

Influence of corrosion on wear and brake particle emissions of alumina-coated and uncoated cast iron brake discs

Hard alumina-based coatings can be applied to cast iron brake discs using a plasma electrolytic aluminating (PEA) process to enhance wear and corrosion resistance and reduce brake particle emissions. This work was first to study the influence of friction wear on corrosion property and then investigate the influence of corrosion on brake particle emissions from cast iron discs through comparison of

HMGCR and rosuvastatin regulates GLP-1 secretion and expression - a translational study

CONTEXT: Statin use is associated with increased risk of type 2 diabetes and mild hyperglycemia. The underlying mechanisms are not well studied and the effect of statin treatment on GLP-1 secretion or production are unknown.OBJECTIVE: To assess the effects of rosuvastatin on GLP-1 secretion and production.METHODS: We performed association studies in the Malmö Diet and Cancer study cardiovascular c

Aerosol, Clouds and Trace Gases Research Infrastructure (ACTRIS): The European Research Infrastructure Supporting Atmospheric Science

The Aerosol, Clouds and Trace Gases Research Infrastructure (ACTRIS) officially became the 33rd European Research Infrastructure Consortium (ERIC) on 25 April 2023 with the support of 17 founding member and observer countries. As a pan-European legal organization, ACTRIS ERIC will coordinate the provision of data and data products on short-lived atmospheric constituents and clouds relevant to clim

Characterization of occupational exposure to air pollutants during asphalt milling and paving

OBJECTIVES: Asphalt is frequently used as road pavement and consists of bitumen as a binder, and fillers. Bitumen consists of a complex mixture of hydrocarbons, where a minor component is polycyclic aromatic hydrocarbons (PAHs). Many PAHs are classified as carcinogenic to humans. Bitumen fumes from road paving have been classified as possibly carcinogenic. Paving and milling are open processes gen

The Effects of Encounters on Planetary Systems in Stellar Clusters

Extrasolar planets are found to be on orbits very different from those of the planets in the solar system. Gas-giant planets have been found on orbits tighter than that of the planet Mercury, often with very high eccentricities. These orbits are surprising; models of planet formation suggest that gas giants should be found on circular orbits with similar size to those of solar-system gas giants.

Water use strategies and ecosystem-atmosphere exchange of CO2 in two highly seasonal environments

We compare assimilation and respiration rates, and water use strategies in four divergent ecosystems located in cold-continental central Siberia and in semi-arid southern Africa. These seemingly unrelated systems have in common a harsh and highly seasonal environment with a very sharp transition between the dormant and the active season, with vegetation facing dry air and soil conditions for at le

Epitope-specific recognition of type II collagen by rheumatoid arthritis antibodies is shared with recognition by antibodies that are arthritogenic in collagen-induced arthritis in the mouse

Objective. To analyze the fine specificity of IgG autoantibodies in sera from rheumatoid arthritis (RA) patients for type II collagen (CII) epitopes that are arthritogenic in collagen-induced arthritis (CIA), a relevant murine model of RA. Methods. For enzyme-linked immunosorbent assay (ELISA) analysis of conformation-dependent autoantibody binding, recombinant chimeric collagens that harbor the r

The CRIRES search for planets around the lowest-mass stars. I. High-precision near-infrared radial velocities with an ammonia gas cell

Radial velocities measured from near-infrared (NIR) spectra are a potentially powerful tool to search for planets around cool stars and sub-stellar objects. However, no technique currently exists that yields NIR radial velocity precision comparable to that routinely obtained in the visible. We are carrying out an NIR radial velocity planet search program targeting a sample of the lowest-mass M dwa

Structure, luminescence, and dynamics of Eu2O3 nanoparticles in MCM-41

The structure, luminescence spectroscopy, and lifetime decay dynamics of Eu2O3 nanoparticles formed in MCM-41 have been investigated. Both X-ray diffraction and high-resolution transmission electron microscopic observations indicate that Eu2O3 nanoparticles of monoclinic structure are formed inside channels of MCM-41 by heating at 140 degreesC. However, heat treatment at 600 or 700 degreesC causes

Electron localization following attosecond molecular photoionization

For the past several decades, we have been able to directly probe the motion of atoms that is associated with chemical transformations and which occurs on the femtosecond (10(-15)-s) timescale. However, studying the inner workings of atoms and molecules on the electronic timescale(1-4) has become possible only with the recent development of isolated attosecond (10(-18)-s) laser pulses(5). Such pul

Heart or lung transplanted patients' retrospective views on information and support while waiting for transplantation.

AIMS AND OBJECTIVES: To describe the patients' retrospective experiences of the information and support they received while on the heart or lung transplant waiting list. BACKGROUND: Patients differ in the way that they cope with the time spent waiting for a heart or lung transplant. Patients must already before the transplantation be taught about a new lifestyle, risk factors, medication, food res

Polarization Transfer Solid-State NMR for Studying Surfactant Phase Behavior.

The phase behavior of amphiphiles, e.g., lipids and surfactants, at low water content is of great interest for many technical and pharmaceutical applications. When put in contact with air having a moderate relative humidity, amphiphiles often exhibit coexistence between solid and liquid crystalline phases, making their complete characterization difficult. This study describes a (13)C solid-state N

In-hospital vs. 30-day mortality in the critically ill - a 2-year Swedish intensive care cohort analysis

BackgroundStandardised mortality ratio (SMR) is a common quality indicator in critical care and is the ratio between observed mortality and expected mortality. Typically, in-hospital mortality is used to derive SMR, but the use of a time-fixed, more objective, end-point has been advocated. This study aimed to determine the relationship between in-hospital mortality and 30-day mortality on a compre