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A generic search for anomalous production of events with at least three charged leptons is presented. The data sample consists of pp collisions at TeV collected in 2012 by the ATLAS experiment at the CERN Large Hadron Collider, and corresponds to an integrated luminosity of 20.3 fb(-1). Events are required to have at least three selected lepton candidates, at least two of which must be electrons o
For the first time, Pulsed Field Gradient-Nuclear Magnetic Resonance, a powerful noninvasive tool for studying the dynamics and structure of complex-gels, has been used to measure diffusion of probe molecules in aqueous solutions/gels of noncommercial purified pig gastric mucin (PGM), in a concentration range up to 5 wt%. Complementary data were obtained from rheology measurements. The combination
Huntington's disease (HD) is a devastating neurodegenerative disorder caused by an expanded CAG repeat in the gene encoding huntingtin, a protein of unknown function. Mutant huntingtin forms intracellular aggregates and is associated with neuronal death in select brain regions. The most studied mouse model (R6/2) of HD replicates many features of the disease, but has been reported to exhibit only
Palaeomagnetic analyses were conducted on two varved lake-sediment sequences in northern Sweden. The magnetic properties of the sediment sequences are dominated by stable single-domain magnetite with characteristics typical of bacterial magnetosomes. Alternating field demagnetization measurements indicate that the single-domain magnetite is the dominant carrier of a stable natural remanent magneti
OBJECTIVE: The aim of this study was to delineate the use of hormone replacement therapy (HRT) among women who were born between December 2, 1935, and December 1, 1945, and living in the Lund area of southern Sweden and to analyze factors that contribute to the acceptance and continuation of HRT. METHODS: All women received a generic questionnaire pertaining to demographic background, lifestyle, h
Popular Abstract in Swedish Denna avhandling fokuserar på frågan om försoning och (sökandet efter) värdegemenskap. Värden sätts in i ett större sammanhang, i ett så kallat "moraliskt landskap". Avhandlingen beskriver först olika hinder för försoning och dialog i Nordirland och Sydafrika i form av följande komponenter av det moraliska landskapet: -Erfarenheter (av trauma, segregation, ojämlikhet) -In Northern Ireland and South Africa obstacles to reconciliation were found in these elements of a “moral landscape”: – Experiences of trauma, separation and inequalities, – Divergent views of the conflict and of “the other”, – Opposing identifications and loyalties, – Norms for interaction, – Contestant interpretations of values such as “peace” and “justice”. This study describes how these obstac
Surveys of prescribing patterns in both hospitals and primary care have usually shown delays in translating the evidence from clinical trials of pharmacological agents into clinical practice, thereby denying patients with heart failure (HF) the benefits of drug treatments proven to improve well-being and prolong life. This may be due to unfamiliarity with the evidence-base for these therapies, the
Human islet amyloid polypeptide (hIAPP), a pancreatic islet protein of 37 amino acids, is the main component of islet amyloid, seen at autopsy in patients with type 2 diabetes mellitus (DM2). To investigate the roles of hIAPP and islet amyloid in DM2, we generated transgenic mice expressing hIAPP in their islet beta cells. In this study, we found that after a long-term, high-fat diet challenge isl
Characterizing population fluctuations and their causes is a major theme in population ecology. The debate is on the relative merits of density-dependent and density-independent effects. One paradigm (revived by the research on global warming and its relation to long-term population data) states that fluctuations in population densities can often be accounted for by external noise. Several empiric
Objective. Rosiglitazone (RSG) has been reported to reduce blood pressure (BP) in patients with type-2 diabetes, but similar effects in non-diabetic people with insulin resistance is less clear. Our aim was to test the long-term BP-lowering effects of RSG compared with placebo. Methods. We recruited participants for BP evaluation of RSG treatment from a larger intervention trial. Office BP was rec
Brent geese were tracked by satellite telemetry from spring staging areas in Denmark to Arctic breeding areas in Svalbard and Greenland in 1997 and 2001. From estimated departure masses and carcass analysis we used flight mechnical theory to estimate maximum flight ranges of both sexes, and remaining stores of fat and protein upon arrival in females. Model predictions suggested that all birds but
Basis for preliminary individual study plan ISP Department of Biology Emma Kritzberg, Director of Postgraduate Studies Klas Flärdh, Director of Postgraduate Studies Page 1 of 2 2 Page 3 of 2 BASIS FOR PRELIMINARY INDIVIDUAL STUDY PLAN Preliminary plan for the education and thesis project The individual study plan should be established as soon as possible after the PhD student is admitted. There th
https://www.biologi.lu.se/internt/sites/biologi.lu.se.internt/files/2022-03/Step2PrelPlanEduThesisProj.docx - 2026-06-25
Apolipoprotein E (ApoE) is a polymorphic protein that plays a major role in lipid metabolism in the central nervous system and periphery. It has three common allelic isoforms, ApoE2, ApoE3 and ApoE4, that differ in only one or two amino acids. ApoE isoforms have been associated with the occurence and progression of several pathological conditions, such as coronary atherosclerosis and Alzheimer's d
