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he study purpose is to determine whether numeric and/or graphic ST measurements added to the display of the 12-lead electrocardiogram (ECG) would influence cardiologists' decision to provide myocardial reperfusion therapy. Twenty ECGs with borderline ST-segment deviation during elective percutaneous coronary intervention and 10 controls before balloon inflation were included. Only 5 of the 20 ECGs
Abstract We present a practical protocol for the assignment of values to serum proteins in a Target Material using a Reference Material. This protocol is based on the model of Direct Value Transfer between serum matrices and is intended to improve the value assignment of commercial calibrators using the Reference Material CRM 470 (now labeled ERM-DA 470) or similar reference materials. The procedu
ObjectiveTo evaluate if adding esketamine and clonidine has positive effects on postoperative pain, postoperative nausea and vomiting, and quality of recovery in patients who are at high risk for postoperative pain.DesignPatient- and assessor-blinded, superiority, randomised controlled trial.SettingSingle centre between 2022 and 2024.Patients125 adult patients, ASA I – II, planned for elective lap
Objective: To estimate the effect on healthcare resource use after introducing the World Health Organization diagnostic criteria (WHO-2013) for gestational diabetes mellitus (GDM) compared to former criteria in Sweden (SWE-GDM). Design: A cost-analysis alongside the Changing Diagnostic Criteria for Gestational Diabetes (CDC4G) randomised controlled trial. Setting: Sweden, with risk-factor based sc
Integrated pest management (IPM) is an important tool for sustainable crop production. IPM includes a diversity of methods, e.g., the use of biological control agents (BCAs) for disease control or growth promotion. While there is an increasing interest in the use of BCAs, less is known about their environmental costs and benefits on wild species, such as wild crop relatives. For example, a BCA may
The mental health of the health workforce has been receiving more attention, especially since the pandemic. Levels of burnout, moral injury, and mental disorders, including suicide, among physicians are cause for concern. Healthcare leadership in workplaces plays a crucial role in addressing this important issue, which is also related to the ability to attract and retain physicians. This chapter p
Background and objective: Although cardiovascular toxicity from modern systemic treatments in metastatic hormone-sensitive prostate cancer (mHSPC) remains a concern, real-world data are limited. We aimed to characterise patients treated for mHSPC across multiple large cohorts and estimate cardiovascular adverse event (AE) risks. Methods: Leveraging PIONEER's Big Data platform, with databases stand
A search for R-parity-violating supersymmetry in final states with high jet multiplicity is presented. The search uses 140 fb−1 of proton-proton collision data at s = 13 TeV collected by the ATLAS experiment during Run 2 of the Large Hadron Collider. The results are interpreted in the context of R-parity-violating supersymmetry models that feature prompt gluino-pair production decaying directly to
A combination of searches for new heavy spin-1 resonances decaying into different pairings of W, Z, or Higgs bosons, as well as directly into leptons or quarks, is presented. The data sample used corresponds to 139 fb−1 of proton-proton collisions at s = 13 TeV collected during 2015–2018 with the ATLAS detector at the CERN Large Hadron Collider. Analyses selecting quark pairs (qq, bb, tt¯, and tb)
Histatins are a family of multifunctional, cationic histidine-rich saliva peptides. The most prominently represented are Histatin 1, Histatin 3, and Histatin 5. Despite considerable similarities in primary structure, the three members are known to display varied antimicrobial properties and healing abilities. This study aims to provide a detailed structural comparison of Histatin 1, Histatin 3, an
INTRODUCTION: Blood-based biomarkers have demonstrated high accuracy for identifying Alzheimer's disease (AD) pathology. However, the lack of representative cohorts creates a knowledge gap regarding their real-world applicability. We examined the influence of ethnicity on the diagnostic accuracy of plasma tau phosphorylated at threonine 217 (p-tau217) in identifying AD. METHODS: A total of 1170 mi
Introduction As care and rehabilitation poststroke are increasingly moving into persons’ home environment, the importance of support from social networks in self-management and rehabilitation has emerged as an important topic for research and practice. While there are instruments used to assess social support and collective efficacy, a clearer scope of the availability and quality of these instrum
Objectives Early detection of neurosensory injury among workers exposed to hand-arm vibration is crucial. The aim of our study was to evaluate the diagnostic test performance of clinical point-of-care testing using a tuning fork and temperature rollers in relation to vibrotactile and thermal quantitative sensory testing. Methods We recruited 225 vibration-exposed workers who underwent clinical poi
Background: Japan lacks efficient assessment tools for occupational balance (OB) in people with mental illness (MI). Aims/objectives: We investigated the test–retest reliability and construct validity of a Japanese version of the Satisfaction with Daily Occupations and Occupational Balance (SDO-OB-J) for people with MI. Methods: SDO-OB-J interviews were conducted twice at a 2-week interval. Result
By 2050, electric vehicles (EVs) are expected to be 40% of all cars on the road1. In some countries like Norway, more than 90% of the new cars sold are electric2. This rise in EVs presents challenges to the current electricity infrastructure to meet this rapid increase in electricity demand. In this study, we simulate urban residential electricity demand using an agent-based model to investigate t
The Intergovernmental Panel on Climate Change needs to do more to include the expertise and voices of women, even as numbers and policies improve.
This study investigated the birth prevalence of cleft lip and/or palate (CL/P) in Sweden between 2000 and 2020 using data from the Swedish National Medical Birth Register, which includes over 97% of children born in the country, and its subregister the National Register of Congenital Anomalies. The dataset included 2,230,771 anonymized children, with the variables year of b
Background: With the availability of a wrist-worn device capable of acquiring two ECG leads with a single touch, synthesis of the 12-lead ECG may be accomplished to facilitate clinical interpretation. Objective: This study proposes an echo state network (ESN) for synthesizing the 12-lead ECG from two leads simultaneously acquired using a wrist-worn device. Methods: The wrist-worn device, equipped
