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Introduction Despite the improvements in diabetes management by continuous glucose monitoring (CGM) it is difficult to capture the complexity of CGM data in one metric. We aimed to develop a clinically relevant multidimensional scoring model with the capacity to identify the most alarming CGM episodes and/or patients from a large cohort. Research design and methods Retrospective CGM data from 2017
Objectives: Lung squamous cell carcinoma (LUSC) is associated with a poor prognosis and a lack of specific treatment options. The dysregulation of activin A (ActA) has been reported in various malignancies. Herein, we investigated the diagnostic and prognostic significance of ActA in LUSC. Materials and methods: ActA concentrations were measured using ELISA in plasma samples of 128 LUSC patients (
Background: Neutrophil gelatinase-associated lipocalin (NGAL) has been suggested as the most promising biomarker of acute kidney injury. However, there are no reliable data on analytical sensitivity and reference limits of urinary NGAL (uNGAL) assay in pediatric age. The aim of the present study is to evaluate the analytical sensitivity and the reference range of uNGAL measured in urine specimens
CONTEXT: The well-known side-effect profile of androgen-deprivation therapy (ADT) has significant quality-of-life (QoL) implications. Intermittent androgen deprivation (IAD) alternates androgen blockade with treatment cessation to allow hormonal recovery between treatment cycles, thus potentially improving tolerability and QoL. OBJECTIVE: To evaluate available evidence regarding the efficacy and t
“Die Unruhe und Ungewissheit sind unser Theil”, writes Goethe in a letter to the German novelist Sophie von la Roche in 1774. But is it the incalculable and indeterminate that cause disquiet, or is it our bustling pursuit of knowledge that makes us uncertain? Contemporary psychologists have taught us a great deal about the way we perceive risks and about the way affects and emotions influence our
Several risk factors for severe non-proliferative and proliferative retinopathy in type 1 diabetes mellitus have been proposed without explaining the rapid progression of retinopathy in some patients. Since GAD65 autoantibodies (GAD65Abs) are detected against glutamic acid decarboxylase (GAD), which is mainly expressed in islets and nervous tissue in type 1 diabetic patients, the aim of the presen
Many breeding attempts in birds do not result in any fledged young due to predation on eggs or young. Consequently, the influence of time constraints on reproductive decisions are integrated parts of the reproductive behaviour of birds breeding within short, seasonal climate zones. In this study. I mimicked nest predation by removing blue tit (Parus caeruleus) clutches shortly after completion. Ar
The European Union (EU) has laid down very clear objectives for the reduction of greenhouse gases in the hope that it will prevent or mitigate climate change. Political incentives are used to make the power industry adopt changes in order to reach these EU targets. In this thesis, some solutions that could help power companies meet the EU objectives are evaluated. Thermodynamic models have been de
Resolving complexes of closely related and cryptic insect species can be challenging, especially when dealing with rare and protected taxa that are difficult to collect for genetic and morphological analyses. Until recently, populations of the genus Osmoderma (Scarabaeidae), widespread in Europe, were treated as a single species O. eremita (Scopoli, 1763) in spite of observed geographic variation
BACKGROUND: Long commutes by car are stressful. Most research studying health effects of commuting have summarized cross-sectional data for large regions. This study investigated whether the levels of stress and individual characteristics among 30–60 min car commuters were similar across different places within the county of Scania, Sweden, and if there were changes over time. METHODS: The study p
Background: Myocardial fibrosis, expressed as late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging (CMR), is an important risk factor for malignant cardiac events in hypertrophic cardiomyopathy (HCM). However, CMR is not easily available, expensive, also needing intravenous access and contrast. Objective: To determine if derived vectorcardiographic spatial QRS-T angles, an aspec
REVIEW Current Diabetes Reports (2025) 25:57 https://doi.org/10.1007/s11892-025-01612-3 Abbreviations ABIS All Babies in Southeast Sweden ADA American Diabetes Association ADIR Pediatric General Population for Detection of Pre-Symptomatic Type 1 Diabetes ASK Autoimmunity Screening in Kids DKA Diabetic Ketoacidosis ELSA EarLy Surveillance for Autoimmune Diabetes FDA United States Food and Dr
Den svenska företagsbeskattningen baseras på att varje enskilt företag är ett självständigt skattskyldigt subjekt. Däremot finns vissa möjligheter att beakta flera företags resultat av näringsverksamhet när dessa ingår i en koncern. Ett alternativ som har ställts upp är de skatterättsliga koncernbidragen. Då koncernbidragsreglerna aktualiseras och en värdeöverföring har skett mellan två företag inSwedish corporate taxation is based on the fact that each individual company is an independently taxable subject. On the other hand, in some circumstances it is possible to take into account several companies' income of economic activities, when these are part of a corporate group. One option available is the group contribution. If the rules concerning group contributions are applicable and a
Popular Abstract in Swedish Skador på skelettet kan uppstå efter bl.a. olyckor, tumörkirurgi eller strålning. Ofta är sådana skador mycket handikappande då de påverkar kroppens funktion, stabilitet och utseende. Om benvävnad saknas eller måste bytas ut använder man sig idag av mikrokirurgiska metoder, där man flyttar kroppseget ben från ett ställe till ett annat. Tyvärr innebär detta att man skapaBone deficiencies, caused by malformations, trauma or adverse effects from medical treatments, are a clinical challenge and often associated with reduced physical function and quality of life. Autologeous bone grafts can be used to reconstruct skeletal defects, but the right size and quality of bone might not always be available and even so, donor-site morbidity might follow. A pre-fabricated or t
The European Myeloma Network has organized two workshops on fluorescence in situ hybridization in multiple myeloma. The first aimed to identify specific indications and consensus technical approaches of current practice. A second workshop followed a quality control exercise in which 21 laboratories analyzed diagnostic cases of purified plasma cells for recurrent abnormalities. The summary report w
Poland, as many other countries, has ambitions to increase the use of renewable energy sources. In this paper, we review the current status of bioenergy in Poland and make a critical assessment of the prospects for increasing the share of bioenergy in energy supply, including policy implications. Bioenergy use was about 4% (165PJ) of primary energy use (3900PJ) and 95% of renewable energy use (174
Humanities for medical students? A qualitative study of a medical humanities curriculum in a medical school program Caroline Wachtler, Susanne Lundin and Margareta Troein Lund University, Department of Clinical Sciences, General Practice/Family Medicine, Malmö University Hospital, SE 20502 Malmö, Sweden 2Lund University, Department of Ethnology, Finngatan 10, SE 223 62 Lund, Sweden BMC Medical Ed
Popular Abstract in Swedish I denna avhandling behandlas brosk proteiners roll såsom antigen och tillgänglighet av immunsystemet i artrit. Sex artiklar omfattas, där fyra presenterar nya djur modeller för reumatoid artrit (RA), en visar hur en genetisk störning av ett broskprotein kan förvärra artrit och den sista hur posttransnationell modifiering av kollagen typ II (CII) påverkar T-cells toleranIn this thesis the role of cartilage proteins and their potential as antigen and availability to the immune system in arthritis were investigated. Six papers are included; where four present new animal models for Rheumatoid arthritis (RA), one shows how genetic disorders in cartilage may affect arthritis and the last how posttranslational modification of collagen type II (CII) affects tolerance. P
I takt med att hållbarhet blir viktigare söker många företag inom jordbrukssektorn lösningar för att fasa ut fossila drivmedel. Utmaningen blir ännu mer komplex när ersättningen ska vara kompatibel med en existerande fordonsflotta, utan investering i nya fordon. Denna studie jämförde fyra kommersiellt tillgängliga och förnybara drivmedel med referensbränslet diesel. De undersökta drivmedlen är HVAs sustainability becomes more important in today's society, many companies in the agricultural sector are looking for new alternatives to fossil fuels. The challenge becomes even more complex when the replacement must be compatible with an existing vehicle fleet, without requiring new investments in vehicles. This report compares four commercially available and renewable fuels, using convent
PUC2018 other cover.indd 1 Master’s Programme in International Human Rights Law 2018-2020FLPA Faculty of Law and Public Affairs Sila Samadhi Pañña 2 3 The Master’s Programmes in International Human Rights Law is offered by the Faculty of Law and Public Affairs at Paññasastra University of Cambodia (PUC-FLPA). Offered in English language, it is an international level programme that draws on the aca
https://rwi.lu.se/app/uploads/2018/02/PRINT-PUC-CambodiaMaster2018.pdf - 2026-07-17
