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We have previously identified tagSNPs at 8q24.21 influencing glioma risk. We have sought to fine-map the location of the functional basis of this association using data from four genome-wide association studies, comprising a total of 4147 glioma cases and 7435 controls. To improve marker density across the 700 kb region, we imputed genotypes using 1000 Genomes Project data and high-coverage sequen
In this roundtable, we will discuss the role of the kappa, the framing text in a compilation thesis, in STEM doctoral education. Based on two runs of the new courseFraming your research – thesis frames and knowledge contribution for doctoral students at LTH and a focus group discussion with experienced examination committee members and supervisors, we argue that the kappa is an emergent genrestill
Studies on mantle cell lymphoma (MCL) emphasize that patients with progression of disease (POD) ≤24 months have inferior prognosis compared to patients with later POD. This population-based study assessed the impact of POD on overall survival (OS) by timing of progression and first-line treatment. A total of 1186 MCL patients diagnosed 2006–2018 were identified in the Swedish lymphoma register. PO
Background and purpose: Few studies on magnetic resonance imaging (MRI) only head and neck radiation treatment planning exist, and none using a generally available software. The aim of this study was to evaluate the accuracy of absorbed dose for head and neck synthetic computed tomography data (sCT) generated by a commercial convolutional neural network-based algorithm. Materials and methods: For
During the last couple of decades, we have witnessed a proliferation of the project as an organizational solution in sectors as diverse as IT, housing, social services, education and culture. Despite a growing interest in the phenomenon, we know surprisingly little of how processes of public sector projectification unfold in practice, especially at local government level. This article uses an inst
Objectives To study the value of combining individual- and neighborhood-level sociodemographic data to predict study participation and assess the effects of baseline selection on the distribution of metabolic risk factors and lifestyle factors in the Swedish CardioPulmonary bioImage Study (SCAPIS). Methods We linked sociodemographic register data to SCAPIS participants (n = 30,154, ages: 50-64 yea
Courts and judicial processes have emerged as arenas on which political and social contestations over racism increasingly is taking place in Sweden. This presentation is part of a larger project where we analyse cases in which political struggles around racism and migration have moved into courts. The overall purpose is to understand what kind of space courts provide for protection from, and debat
Using judges and stage actors as instructive polar types this article elucidates factors that influence the inclination to empathise. Both come in close contact with dramatic life stories on an everyday basis but approach empathy from contrasting vantage points: emotional distance versus emotional engagement. Similarities between these polar types can thus disentangle some of the factors that infl
Corporate complicity in international crimes falls under the broader category of state-corporate crime, which encompasses the intersection between state and corporate misconduct. The concept of 'corporate complicity' includes both civil and criminal liability and involves various forms of involvement (e.g., direct participation, assistance, facilitation, benefiting, silent approval) and motivation
Background: 25-hydroxyvitamin D3 (25(OH)D3) affects immune function, bone health, and reproduction. The precursor of 25(OH)D3, vitamin D3, is synthesized upon ultraviolet (UV) radiation exposure, the levels of which vary. Methods: In a one-year observational study, we used multiple statistical approaches to examine 25(OH)D3 metabolism and UV exposure in 217 healthy men (aged 30–50 years) not using
A thorough understanding of the longitudinal phase space (LPS) of the electron beam is of great advantage to any modern linear accelerator (linac), and of critical importance for operating a free electron laser (FEL). While a transverse deflecting structure (TDS) allows full characterization of a beam’s LPS, measurements with a TDS system are often destructive and operationally complex. We present
The current paper presents the results of behavioural observations in a field experiment with automated shuttles in Oslo, Norway. Video observations were conducted at five fixed locations along a challenging 1.2 km automated shuttle line with varying traffic conditions. Observed interactions between vulnerable road users and automated shuttles were coded using a predefined codebook, which allowed
This article examines early Boy Scout camps as events of national display and localized internationalism. By detailing how the camp culture of the Swedish Boy Scout movement facilitated transnational integration, the article shows that internationalism as localized practice can be observed in summer camp environments from the early days of the twentieth century. Reports from these early camps high
This article reports the result of a survey designed to investigate the degree of uncertainty by which a representative sample of Swedish households hold their perceptions and expectations of inflation. The public displays hardly any uncertainty concerning the direction of change of the price level as measured by the ratio of ‘don’t know’ answers. However, when asked for numerical estimates of theThis article reports the result of a survey designed to investigate the degree of uncertainty by which a representative sample of Swedish households hold their perceptions and expectations of inflation. The public displays hardly any uncertainty concerning the direction of change of the price level as measured by the ratio of ‘don’t know’ answers. However, when asked for numerical estimates of the
True Partnership as True Learning is ultimately a book about satisfaction. It is a book about working at, and being part of the Swedish law firm Mannheimer Swartling. More specifically, it is a book about knowledge sharing. The aim of this book is to outline a discussion on how, and why, knowledge is shared in practice, and what it takes to achieve an elite identity organization and sustainable surue Partnership as True Learning is ultimately a book about satisfaction. It is a book about working at, and being part of the Swedish law firm Mannheimer Swartling. More specifically, it is a book about knowledge sharing.The aim of this book is to outline a discussion on how, and why, knowledge is shared in practice, and what it takes to achieve an elite identity organization and sustainable succ
Anterior Uveitis (AU) is the inflammation of the anterior part of the eye, the iris and ciliary body and is strongly associated with HLA-B*27. We report AU exome sequencing results from eight independent cohorts consisting of 3,850 cases and 916,549 controls. We identify common genome-wide significant loci in HLA-B (OR = 3.37, p = 1.03e-196) and ERAP1 (OR = 0.86, p = 1.1e-08), and find IPMK (OR =
Open science aims to improve research accessibility, replicability, and consequently its quality. Empirical software engineering entails both data and artifacts, which may be shared more or less openly, to support transparency. However, the trade-offs involved in balancing the openness against integrity and secrecy concerns need methodological guidance. Aim. We aim to derive such advice, based on
This article analyses the role of the Soviet political police and the KGB state security in suppressing large workers' protests in Novocherkassk in 1962. The aim is not only to study the actions of the KGB during the crisis itself, but above all to show how the events in Novocherkassk contributed to the subsequent change in the overall character of this repressive service and, more generally, the This essay analyses the role of the KGB, the Soviet state security and political police, in suppressing large workers’ protests in Novocherkassk in early June 1962. The aim is not only to study the actions of the KGB during the crisis itself, but to show how events in Novocherkassk and the subsequent brutal punishment of their main actors contributed to the subsequent change in the overall charact
Popular Abstract in Swedish Det samlade temat för de sju artiklarna i denna avhandling är att se på hur modern national-ekonomiska teori, som behandlar problem rela-terade till förekomsten av asymmetrisk infor-mation, kan användas för att studera insatser för åstadkomma bättre hälsa. Artiklarna rör dels vård på sjukhus,dels produktionen av läkemedel. För sjukhusen handlar det om hur man via olika The common theme of this thesis is the analysis of asymmetric information when applied to the market for health care production. The thesis consists of six more or less independent papers and an introduction to the thesis were purpose and methodology are stated (part one). Part two is an investigation into the pricing of pharmaceuticals in Sweden. This chapter deals with issues such as cost sharin
