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We evaluated the association between cardiopulmonary bypass (CPB) time during surgery for acute type A aortic dissection (ATAAD) and mid-term survival. Data of 1122 patients who underwent surgery for ATAAD in eight Nordic centers from January 2005 to December 2014 were retrospectively analyzed. An adjusted logistic regression analysis was performed to investigate the association of incremental 30
This contribution discusses relations between the Swedish SAC and the legislature (Riksdag), focusing on how Sweden balances popular sovereignty with judicial independence. The analysis focuses on the legislature's influence on the SAC and – on the other hand – the SAC and its judges’ impact on the legislature, especially the constitutional control of draft legislation carried out by the Council oThis contribution discusses relations between the Swedish SAC and the legislature (Riksdag), focusing on how Sweden balances popular sovereignty with judicial independence. The analysis focuses on the legislature's influence on the SAC and – on the other hand – the SAC and its judges’ impact on the legislature, especially the constitutional control of draft legislation carried out by the Council o
A classic in the field of Medical Humanities, the late Philip Sandblom's study of art and ill health first appeared in English in 1982. This is a new, extended version, based on the definitive Swedish edition of 2022.In riveting analyses of the interplay between illness and art, music, and literature, Creativity and illness shows how various diseases and disabilities have affected the works of famA pioneering work in the field of Medical Humanities, first published as Creativity and disease in 1982, Creativity and illness now appears in a fresh, extended version based on the definitive Swedish edition published in 2022. A renowned surgeon, Philip Sandblom was also a connoisseur of the fine arts, and throughout his life he was fascinated by the interplay between art and health. Having start
Studies on mantle cell lymphoma (MCL) emphasize that patients with progression of disease (POD) ≤24 months have inferior prognosis compared to patients with later POD. This population-based study assessed the impact of POD on overall survival (OS) by timing of progression and first-line treatment. A total of 1186 MCL patients diagnosed 2006–2018 were identified in the Swedish lymphoma register. PO
Background: 25-hydroxyvitamin D3 (25(OH)D3) affects immune function, bone health, and reproduction. The precursor of 25(OH)D3, vitamin D3, is synthesized upon ultraviolet (UV) radiation exposure, the levels of which vary. Methods: In a one-year observational study, we used multiple statistical approaches to examine 25(OH)D3 metabolism and UV exposure in 217 healthy men (aged 30–50 years) not using
Aims To explore whether circulating matrix metalloproteinase-2 (MMP-2), MMP-9, MMP-9/neutrophil gelatinase-associated lipocalin, MMP-9/tissue inhibitor of metalloproteinase-1 (TIMP-1), MMP-14, TIMP-2 and TIMP-3 were associated with the severity and progression of diabetic retinopathy (DR) in patients with type 1 diabetes (T1D). Methods Baseline and prospective analyses were conducted over a period
The integration of high-precision cellular localization and machine learning (ML) is considered a cornerstone technique in future cellular navigation systems, offering unparalleled accuracy and functionality. This study focuses on localization based on uplink channel measurements in a fifth-generation (5G) new radio (NR) system. An attention-aided ML-based single-snapshot localization pipeline is The integration of high-precision cellular localization and machine learning (ML) is considered a cornerstone technique in future cellular navigation systems, offering unparalleled accuracy and functionality. This study focuses on localization based on uplink channel measurements in a fifth-generation (5G) new radio (NR) system. An attention-aided ML-based single-snapshot localization pipeline is
BACKGROUND: Monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM) are asymptomatic precursor conditions to multiple myeloma and related disorders. Smoldering multiple myeloma is distinguished from MGUS by 10% or greater bone marrow plasma cells (BMPC) on sampling, has a higher risk for progression, and requires specialist management.OBJECTIVE: To develop a
Background: Brief Admission by self-referral (BA) is a crisis-management intervention standardized for individuals with self-harm at risk of suicide. We analyzed its health-economic consequences. Materials and methods: BA plus treatment as usual (TAU) was compared with TAU alone in a 12-month randomized controlled trial with 117 participants regarding costs for hospital admissions, coercive measur
Radio Frequency Integrated Circuits (RFICs) play a crucial role in modern wireless communica- tion systems. However, they can achieve high performance only when their internal registers are dynamically and precisely configured. To maintain reliable control while operating in complex multi-antenna environments, several interface techniques have been developed, among which the Serial Peripheral Inte
Aim: Diabetes mellitus type 1 (T1D) has numerous complications including autonomic neuropathy, i.e. dysfunction of the autonomous nervous system. This study focuses on Heat Shock Protein 27 (HSP27), Macrophage Migration Inhibitory Factor (MIF), Plasminogen Activator Inhibitor-1 (PAI-1) and HbA1c and their possible roles in effects of diabetes on the autonomic nervous system.Methods: Patients with Aim Diabetes mellitus type 1 (T1D) has numerous complications including autonomic neuropathy, i.e. dysfunction of the autonomous nervous system. This study focuses on Heat Shock Protein 27 (HSP27), Macrophage Migration Inhibitory Factor (MIF), Plasminogen Activator Inhibitor-1 (PAI-1) and HbA1c and their possible roles in effects of diabetes on the autonomic nervous system. Methods Patients with T
The development of real-time ultrasound in the 1970's made indelible inpact on antenatal care. Assessing foetal growth and detecting deviations from normal in both growth and foetal anatomy became fesible. Expectant parents could also 'see' their foetus. Normal foetal growth parameters at term were consituted and selected parameters from the second trimester were evaluated in the detection of chro
Background: Despite uniform operating techniques, lack of fusion still occurs after ankle arthrodesis. Differences in the biological healing potential may be a factor but the mechanical performance of the arthrodesis construct because of varying bone quality also may be important. Internal compression techniques are preferred because of higher union rates, shorter fusion times, and fewer complicat
BACKGROUND: Our recently reported finding of rapid bi-exponential elimination of free prostate-specific antigen (PSA) after radical retropubic prostatectomy in patients with moderately elevated PSA levels, which contrasted a very slow, linear elimination of PSA complexed to alpha-1-antichymotrypsin (ACT), prompted us to study whether these elimination rates were applicable for patients selected fo
In this work we report on ab initio theoretical results for the magnetic-field-induced 2s 2p P-3(0) -> 2s(2) S-1(0) E1 transition for ions in the beryllium isoelectronic sequence between Z = 5 and 92. It has been proposed that the rate of the E1M1 two-photon transition 2s 2p P-3(0) -> 2s(2) S-1(0) can be extracted from the lifetime of the P-3(0) state in Be-like ions with zero nuclear spin by empl
Base cation weathering (BCw) rate is one of the most influential yet difficult to estimate parameters in the calculation of critical acid loads of nitrogen (N) and sulfur (S) deposition for terrestrial systems. Only the clay correlation-substrate method, a simple empirical model, has been used for estimating BCw rates for forest ecosystems in the conterminous USA and may not be suitable for applic
Objectives: This study investigates whether sequential addition of inverted, (negative) leads from the 24-lead electrocardiogram (ECG) to the orderly sequenced 12-lead ECG would identify a number of leads with which the sensitivity for diagnosis of acute transmural ischemia is significantly increased with minimal loss of specificity. Background: Acute transmural ischemia due to thrombotic coronary
Background and Aims: In a retrospective study using stereotactic body radiotherapy (SBRT) in medically inoperable patients with stage I NSCLC we previously reported a local control rate of 88% utilizing a median dose of 15 Gy x 3. This report records the toxicity encountered in a prospective phase II trial, and its relation to coexisting chronic obstructive pulmonary disease (COPD) and cardiovascu
Background: Recombinant factor VIIa (rFVIIa) is used to treat bleeds in hemophilia patients with inhibitors. A subcutaneous formulation could potentially improve its half-life and make it suitable for prophylactic treatment. Objectives: A study was conducted to determine the safety of subcutaneously administered rFVIIa in patients with hemophilia and the pharmacokinetic profile (including bioavail
