Filetype
Ligand induced activation of the beta-receptor for platelet-derived growth factor (PDGF) leads to activation of Src family tyrosine kinases. We have explored the possibility that the receptor itself is a substrate for Src. We show that Tyr934 in the kinase domain of the PDGF receptor is phosphorylated by Src. Cell lines expressing a beta-receptor mutant, in which Tyr934 was replaced with a phenyal
Background/Aims: We have observed a difference between patients on low-flux hemodialysis (HD) or peritoneal dialysis and patients on hemodiafiltration (HDF) or high-flux HD in the capacity of transmigrated leukocytes to mobilize CD11b in response to inflammatory stimuli compared with healthy subjects. This could be due to different interstitial chemokine concentrations. Methods: We measured concen
The effect of strain and transforming growth factor beta on equine tendon fibroblasts (tenocytes) was assessed in vitro. Tenocytes were isolated from flexor and extensor tendons of horses from foetal to 10 years of age. These cells were cultured until confluent on collagen-coated silicone dishes. Cyclic biaxial strain of 9 +/- 1% was applied at 0.5 Hz for 24 hours with or without added TGFbeta1 or
Each autumn, large numbers of red admirals migrate throughout northern Europe,flying south, to reach areas with conditions suitable for surviving the winter. We observed the visible butterfly migration at Falsterbo peninsula, the southwesternmost point in Sweden, where red admirals are seen most autumns. ying towards the Danish coast on their way to more southern parts of Europe. Weather parameter
The Sound Environment Centre at Lund University was established in March 2005. The centre is the first of its kind, both nationally and internationally. It is tasked with studying sound as a phenomenon, sound worlds and sound environments from a multi- and interdisciplinary perspective. It is a Lund University-wide body for education and research as well as external engagement in general for matte
Humanistiska och teologiska fakulteterna bedriver en bred och varierad verksamhet inom forskning och utbildning som i vid mening syftar till att förstå människan som kulturell och samhällelig varelse. Vi forskar och utbildar inom områden som behandlar kulturmöten, språk, historia, etik, religion, filosofi, konst, musik, litteratur och annat som formar och definierar kulturerna.The Joint Faculties of Humanities and Theology provide research and education in a broad range of subjects, ranging from cultural sciences, history, philosophy, archaeology, languages and literature to theology and religious studies.
Övergripande målet för vår forskning är att undersöka hur miljöfaktorer associerade med utveckling av typ 2-diabetes (T2D) påverkar frisättning av insulin och glukagon från bukspottkörtelns Langerhanska öar. Insulin och glukagon reglerar reciprokt blodets glukosnivåer. Insulin minskar blodglukoskoncentrationer efter måltid, glukagon medverkar till ökade nivåer av glukos vid fasta och ansträngn. ViThe overall objective of our research is to investigate how Type 2 Diabetes (T2D) associated environmental factors effects the islet hormone secretion with a specific focus on how impaired exocytosis is involved in the etiology of the disease. We investigate from a cell physiological perspective the regulation of insulin and glucagon secretion from the pancreatic beta – and alpha cells, respective
En stor del av diabetesforskningen vid Lunds universitet görs inom forskningsmiljön EXODIAB som är ett strategiskt forskningsområde (SFO) i Sverige. Inom EXODIAB har Lunds universitets diabetescentrum (LUDC) och Uppsala universitet ett nära samarbete.A significant part of diabetes research at Lund University is conducted within EXODIAB, which is a strategic research area (SRA) in Sweden. Within EXODIAB, Lund University Diabetes Centre (LUDC) and Uppsala University work closely together.
We are striving towards the identification of disease-modifying mechanisms that protect endogenous insulin release and diabetes development. Ion channels play overarching roles as sensors of cellular activity and control long-term adaptation of the endocrine pancreatic islet to the environmental demands. Our goals concern signals involved in cellular responses to beta-cell overload: 1)Role of vol
We study the adjoint of the double layer potential associated with the Laplacian (the adjoint of the Neumann-Poincaré operator), as a map on the boundary surface Γ of a domain in R3 with conical points. The spectrum of this operator directly reflects the well-posedness of related transmission problems across Γ. In particular, if the domain is understood as an inclusion with complex permittivity ε,
Environmental psychology conducts research, teaching and collaborations focused on the interaction between people and the environment from the perspective of the individual. The subject deals with how people experience their surroundings and are affected by them, as well as how humans affect the environment through their behaviour. The research encompasses the relationship to both the physical a
