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Malaria is a potentially life-threatening disease with approximately half of the world’s population at risk. Young children and pregnant women are hit hardest by the disease. B cells and antibodies are part of an adaptive immune response protecting individuals continuously exposed to the parasite. An infection with Plasmodium falciparum can cause dysregulation of B cell homeostasis, while antibodi
Fibroblast growth factor 23 (FGF23) is a phosphaturic hormone that in recent years has been reported to have significant effects on numerous tissues. Chronic obstructive pulmonary disease (COPD) is associated with hypophosphatemia but the evidence for elevated plasma levels of FGF23 in COPD subjects is ambiguous. Recently, FGF23 has even been shown to be involved in the inflammatory pathways activ
Visualizing geographical phenomena often involve communication of information and relationships through a map in either 2D or 3D. In many cases, the information conveyed through the map is a simplified and symbolic depiction of phenomena that is visible in our physical environment. However, maps are also effective for the communication of geographical phenomena that are hidden or are by nature “in
The Child Behavior Checklist (CBCL) and Youth Self-Report (YSR) are widely used measures of psychiatric symptoms and lately also adapted to the DSM. The incremental validity of adding the scales to each other has not been studied. We validated the DSM subscales for affective, anxiety, attention deficit/hyperactivity (ADHD), oppositional defiant (ODD), conduct problems (CD), and obsessive-compulsiv
Following stroke, attenuation of detrimental inflammatory pathways might be a promising strategy to improve long-term outcome. In particular, cascades driven by pro-inflammatory chemokines interact with neurotransmitter systems such as the GABAergic system. This crosstalk might be of relevance for mechanisms of neuronal plasticity, however, detailed studies are lacking. The purpose of this study w
Regenerative ability varies tremendously across species. A common feature of regeneration of appendages such as limbs, fins, antlers, and tails is the formation of a blastema-a transient structure that houses a pool of progenitor cells that can regenerate the missing tissue. We have identified the expression of von Willebrand factor D and EGF domains (vwde) as a common feature of blastemas capable
Magnesium transporter A (MgtA) is an active transporter responsible for importing magnesium ions into the cytoplasm of prokaryotic cells. This study focuses on the peptide corresponding to the intrinsically disordered N-terminal region of MgtA, referred to as KEIF. Primary-structure and bioinformatic analyses were performed, followed by studies of the undisturbed single chain using a combination o
In this article we present data from two experiments on the association between individual asymmetry and fitness in the winter moth. We performed a mate selection experiment and compared asymmetry and body size of mated and unmated males collected in the field. Individual asymmetry was not associated with copulation probability, adult life span, or body size, even though body size is a reliable in
Hypothesis: Colloidal particles that interact via a long-ranged repulsive barrier in combination with a very short-ranged attractive minimum can “polymerize” to form highly anisotropic structures. Motivated by previous experimental achievements in non-aqueous solvents, and recent theoretical predictions, we hypothesize that it is possible to construct clusters that resemble linear or branched poly
The properties of a cylindrical 1" × 1" and 3" × 3" LaBr3:Ce scintillators (Brillance 380) have been investigated. The first crystal has been analyzed in terms of its self activity due to unstable contaminants emitting a and β particles eventually followed by γ-rays. Coincidence measurements between LaBr3:Ce signals and γ-rays in a HPGe detector were made. The second crystal has been irradiated wi
OBJECTIVE: There is sparse evidence for the association of suitable food substitutions for red and processed meat on the risk of type 2 diabetes. We modeled the association between replacing red and processed meat with other protein sources and the risk of type 2 diabetes and estimated its population impact.RESEARCH DESIGN AND METHODS: The European Prospective Investigation into Cancer (EPIC)-Inte
Oil extraction in the Niger Delta region of Nigeria has long resulted in environmental degradation and social inequalities. While multinational oil companies and the Nigerian Federal Government benefit financially from oil extraction, local communities in the region suffer from widespread pollution that impedes on their ability to practice livelihoods and earn an income. Consequently, militant gro
This thesis examines the exclusion and socioeconomic marginalization of Afro-Latinos in Latin America. This population has historically been put in the ambiguous position of continuous inclusion and alienation within Latin American societies, which serves as the foundation for their marginalization and social exclusion. One way to investigate this unique position is to analyze the negotiation and
The starting point of this study is the perspective of Swedish private forest owners. From that point of view, I aimed to discover the possible influences of values on climate mitigation and biodiversity in Swedish forests. The focus of both climate mitigation and biodiversity is of great importance as these are two major crises the world faces, and yet solutions are often seen as conflicting. By
Anthropogenic activities such as hydropower exploitation have been one of the main drivers of anadromous fish biodiversity loss during the past century. This has led to genetic homogenization and to the reduction of positive mechanisms such as the “portfolio effect”. In this study we propose the first comprehensive analysis of the genetic differences in Salmo salar and Salmo trutta populations in
Due to the fast paced digitalization, marketers are met with higher demands in order to adapt to new contexts for marketing communication and brand management. The social media platform of TikTok is relatively new and rapidly expanding, creating both opportunities and risks for brands. One of the brands who have seized these opportunities is Ryanair, who have attracted 1.6 million followers under
The research examines the effect of tonality on cross-border mergers and acquisitions (M&A) based on press release announcements. The impact of effective communication, tonality, and positive and negative words on the investor's behaviour and firm performance will be analysed to understand the impact on internal and external stakeholders. A comprehensive database of Swedish companies'
