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Construction in rock is associated with risks because knowledge of the geology and ground conditions is limited. Unforeseen rock conditions involve a large risk to the project and can in the end entail delays and extra costs. To minimize the risks, an optimized pre-investigation program has to be conducted where essential information is gathered in order to make the best decisions throughout the c
We raise the question whether there is a rigorous argument favoring one jury system over another. We provide a Bayesian model of deliberating juries that allows for computer simulation for the purpose of studying the effect of jury size and required majority on the quality of jury decision making. We introduce the idea of jury value (J-value), a kind of epistemic value which takes into account the
There are water vapour condensation and two-phase flow in plate heat exchangers when they are used as condensers. Water phase change and flow dynamics modelling is an important but complicated task due to large change in water physical/transport properties across the water liquid-vapour interface boundary. In particular, singular-link behaviour in governing equations is present due to the large st
A Swedish translation of the Barrow Neurological Institute Screen for Higher Cerebral Functions was administered to 52 normal control subjects and 36 patients with well-documented brain dysfunction. Findings replicated those reported in American samples. Level of performance was strikingly similar between Swedish controls and American controls, especially in individuals between 15 and 39 years. Sw
BACKGROUND AND PURPOSE: BBA is a rare type of intracranial aneurysm that is difficult to treat both surgically and endovascularly and is often associated with a high degree of morbidity/mortality. The aim of this study was to present clinical and angiographic results, as well as antiplatelet/anticoagulation regimens, of endovascular BBA treatment by using predominantly stent-assisted coil emboliza
BACKGROUND: In order to determine myocardial salvage, accurate quantification of myocardium at risk (MaR) is necessary. We present a validated novel automatic segmentation algorithm for quantification of MaR by myocardial perfusion SPECT (MPS) in patients with acute coronary occlusion. METHODS AND RESULTS: Twenty-nine patients with coronary occlusion were injected with a perfusion tracer before re
An in-depth article on the controversial artist Boris Lurie.
Background: An increasing number of industrial robots are being programmed using CAR (Computer Aided Robotics). Sensor guidance offers a means of coping with frequent product changes in manufacturing systems. However, sensors increase the uncertainty and to preserve system robustness, a tool is needed that makes it possible to understand a sensor guided robot system before and during its actual op
The vitamin A metabolite and transcriptional modulator retinoic acid (RA) is recognized as an important regulator of epithelial cell homeostasis in several tissues. Despite the known importance of the epithelial compartment of the thymus in T cell development and selection, the potential role of RA in the regulation of thymic cortical and medullary epithelial cell homeostasis has yet to be address
The intensities of hydrogen Lyman-α and Balmer series emission lines as a result of photoexcitation of free CH4 and NH3 molecules at the C 1s and N 1s edges have been measured. For methane, the total fluorescence yield in the visible region (300–650 nm) was also recorded. Excitation functions of the Balmer lines show relative intensity enhancement of Balmer-β emission in comparison with Balmer-α a
Tumors can induce the generation and accumulation of immunosuppressive cells such as myeloid-derived suppressor cells (MDSCs) in a tumor microenvironment, contributing to tumor escape from immunological attack. Although dendritic cell-based cancer vaccines can initiate antitumor immune responses, tumor-educated dendritic cells (TEDCs) involved in the tolerance induction have attracted much attenti
PURPOSE To compare the effect of therapy with anastrozole versus a combination of fulvestrant and anastrozole in women in first relapse of endocrine-responsive breast cancer. PATIENTS AND METHODS Postmenopausal women, or premenopausal women receiving a gonadotropin-releasing hormone agonist, with estrogen receptor- and/or progesterone receptor-positive disease at first relapse after primary trea
Altered microRNA profiles have been demonstrated in experimental models of type 2 diabetes, including in islets of the diabetic Goto-Kakizaki (GK) rat. Our bioinformatic analysis of conserved sequences in promoters of microRNAs, previously observed to be up-regulated in GK rat islets, revealed putative CGCG-core motifs on the promoter of the miR-212/miR-132 cluster, overexpression of which has bee
Major histocompatibility complex (MHC) genes are central for the adaptive immune response against parasites. Here, we investigated potential associations among MHC-I alleles and blood parasite infections in a natural breeding population of a passerine bird, the blue tit Cyanistes caeruleus, in central Spain. We screened both infection status (presence/absence of infection) and infection intensity
