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The fibrillatory rate of the surface ECG during atrial fibrillation (AF) has been suggested for quantification of the individual atrial remodeling, to monitor interventions and to predict the response to different therapies. In this dissertation, the relation between fibrillatory rate of the surface ECG and (1) clinical and echocardiographic variables, (2) the outcome of cardioversion, (3) circula

If water stays on wood surfaces or is trapped in gaps, the wood is supplied with water for a long period of time and high local moisture contents are reached. This can lead to decay by rot fungi, and it is therefore important to avoid such water traps in order to limit the decay rate. This paper presents two methods: one for determination of duration of surface moisture on wood surfaces and one fo

How to best measure working memory capacity is an issue of ongoing debate. Besides established complex span tasks, which combine short-term memory demands with generally unrelated secondary tasks, there exists a set of paradigms characterized by continuous and simultaneous updating of several items in working memory, such as the n-back, memory updating, or alpha span tasks. With a latent variable

BACKGROUND: Health-economic models of diabetes are complex since the disease is chronic, progressive and there are many diabetic complications. External validation of these models helps building trust and satisfies demands from decision makers. We evaluated the external validity of the IHE Cohort Model of Type 2 Diabetes; the impact of using alternative macrovascular risk equations; and compared t

The aim of this study was to evaluate the determinants of kidney function and the role of heritable factors in a sample of 249 siblings free from known cardiovascular disease and without antihypertensive drugs belonging to 110 families. Four different measures and estimates of kidney function were considered. Blood pressure was recorded during 24 h by ambulatory blood pressure monitoring. Heritabi

This paper presents an experimental evaluation of the performance of cubic boron nitride (CBN) tools in the machining of high-chromium white cast iron. Two types of CBN tool materials were evaluated in the tests, including polycrystalline cubic boron nitride (pCBN) and binder-less crystalline cubic boron nitride (bCBN). Performance in terms of the levels of cutting forces, tool wear, surface rough

This feasibility study demonstrates (90)Y quantitative bremsstrahlung imaging of patients undergoing high-dose myeloablative (90)Y-ibritumomab treatment. METHODS: The study includes pretherapy (111)In SPECT/CT and planar whole-body (WB) imaging at 7 d and therapy (90)Y SPECT/CT at 6 d and (90)Y WB imaging at 1 d. Time-activity curves and organ-absorbed doses derived from (90)Y SPECT images were co

Background and purpose: Rat stomach ECL cells secrete histamine and pancreastatin in response to gastrin and pituitary adenylate cyclase-activating peptide-27 ( PACAP). This study applies microdialysis to explore how ECL cells in situ respond to PACAP and gastrin. Experimental approach: Both peptides were administered by microinfusion into the gastric submucosa. The microdialysate was analysed for

Different factors influencing recycling and burial rates of organic carbon (OC) were investigated in the continental margin sediments of the Skagerrak (NE North Sea). Two different areas, one in the southern and one in the northeastern part of the Skagerrak were visited shortly after a spring bloom (March 1999) and in late summer (August 2000). Results suggested that: (1) Organic carbon oxidation

The recognition of bacterial lipopolysaccharide (LPS) is principally mediated by either membrane-bound or soluble form of the glycoprotein CD14 and CD14-associated signal transducer, toll-like receptor 4 (TLR4). Recent findings indicate that the serine protease inhibitor, alpha 1-antitrypsin (AAT), may not only afford protection against proteolytic injury, but may also neutralize microbial activit

1 The immunomodulator Linomide has been shown to protect against septic liver injury by reducing hepatic accumulation of leukocytes although the detailed anti-inflammatory mechanisms remain elusive. This study examined the effect of Linomide on the production of CXC chemokines, including macrophage inflammatory protein-2 (MIP-2) and cytokine-induced neutrophil chemoattractant (KC) and interleukin-

Hematopoietic stem cells (HSCs) are thought to reside in discrete niches through stable adhesion, yet previous studies have suggested that host HSCs can be replaced by transplanted donor HSCs, even in the absence of cytoreductive conditioning. To explain this apparent paradox, we calculated, through cell surface phenotyping and transplantation of unfractionated blood, that similar to 1-5% of the t

Popular Abstract in Swedish Neuroblastom är en allvarlig cancerform som nästan enbart drabbar barn. Denna typ av tumörer hittas i vävnader av det sympatiska nervsystemet (vilket är en del av det icke viljestyrda nervsystemet i kroppen). Allra vanligast är det att tumörerna bildas i binjuren, ett organ placerat strax ovanför njuren. Cancer är en komplex sjukdom och varje tumör är speciell på sitt sCells adapt to oxygen shortage, hypoxia, by inducing a transcriptional shift governed mainly by Hypoxia Inducible Factor (HIF)-1 and HIF-2. In various cancer forms, including neuroblastoma, high expression of HIF-2α correlates with disseminated disease and poor outcome. It has become evident that HIF-1 and HIF-2 are differentially regulated over time and by oxygen levels. HIF-2α is expressed in a

Background: Spot pricing is considered as a significant supplement for building a full-fledged market economy for the Cloud ecosystem. However, it seems that both providers and consumers are still hesitating to enter the Cloud spot market. The relevant academic community also has conflicting opinions about Cloud spot pricing in terms of revenue generation. Aim: This work aims to systematically ide

Institutional theory of the firm focuses on firm boundaries and the activities firms internalize within their hierarchies. However, an examination of disintegrated firms that influences activities beyond the scope of their hierarchies suggests that firms also perform other economic functions. By analysing these functions, the aim of this paper is to suggest a theory of the firm that goes beyond in

Popular Abstract in Swedish Oönskade reaktioner efter vaccination och allergenspecifik immunoterapi - Kontaktallergi för aluminium och kliande knutor För att ett vaccinationsprogram ska fungera krävs kontinuerlig uppföljning av vaccinernas säkerhet vad gäller eventuella oönskade reaktioner. Under de senaste 10 till 15 åren har en ökad oro noterats bland allmänhet och profession beträffande oönskadThe aim of the work presented in this thesis was to investigate two different types of adverse reactions, persistent itching nodules and contact allergy to aluminium, after immunization with aluminium-containing vaccines and aluminium-containing allergen extracts used for allergen-specific immunotherapy (ASIT). The first paper describes active parental reporting of adverse events (AEFIs) after a

The complement system plays a pivotal protective role in the innate immune response to many pathogens including flaviviruses. Flavivirus nonstructural protein 1 (NS1) is a secreted nonstructural glycoprotein that accumulates in plasma to high levels and is displayed on the surface of infected cells but absent from viral particles. Previous work has defined an immune evasion role of flavivirus NS1