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The introduction of L-DOPA pharmacotherapy revolutionized the treatment of Parkinson’s disease close to fifty years ago. Before the discovery of dopamine as a neurotransmitter and its involvement in the disease, these patients had very little aid from medication and were bound to a life without movement. The dopamine neurons in the midbrain are a key player in the circuitry that is responsible for
An excited well-deformed rotational band has been observed in the N = Z odd-odd nucleus Cu-58. The first excited state in this band decays via gamma emission to the spherical states associated with the first minimum in the potential, thus providing for its unambiguous assignment to Cu-58. I, contrast, its bandhead decays via emission of a prompt 2.4(1) MeV proton to an excited state in the daughte
The rescue operations’ environment can impair firefighters’ performance and increase the risk of injuries, e.g., burns and hyperthermia. The bulk and carried weight of heavy protection contributes to lower physical performance, higher metabolic load and internal body heat production. For recommending optimal protection for the tasks and incident scenarios, knowledge of clothing thermal properties
Sustainable energy storage and conversion utforskar innovativa metoder för att effektivt lagra och omvandla energi från olika förnybara källor. Fokus ligger på teknik som avancerade batterier, vätgasproduktion, bränsleceller och termokemiska system samt säkerhetsaspekter på batterilagringssystem. Forskningen syftar till att öka energitätheten, minska kostnaderna och förbättra skalbarheten, vilket
https://www.energy.lth.se/sv/forskning/lagring-och-omvandling-av-energi - 2026-06-25
Background. Flattening filter-free (FFF) beams are an emerging technology that has not yet been widely implemented as standard practice in radiotherapy centers. To facilitate the clinical implementation of FFF, we attempted to elucidate the difference in plan quality and treatment delivery time compared to flattening filter beams (i.e. standard, STD) for several patient groups. We hypothesize that
IntroductionCardiac arrest (CA) survivors often face significant health challenges, including insomnia, which can adversely affect their health-related quality of life. The Minimal Insomnia Symptom Scale (MISS) is a brief, self-reported instrument designed to screen for insomnia. This study aimed to identify the measurement properties of the MISS in CA survivors and to explore a relevant cut-off s
Popular Abstract in Swedish Stärkelsemikrosfärer undersökta i denna avhandling är avsedda för kontrollerad tillförsel av läkemedel som utförs i form av depåpreparat eller slow release-former. Stärkelsemikrosfär är en beredningsform anpassad för inkapsling av protein i terapeutiskt syfte. För att uppnå en kontrollerad frisättning kan stärkelsemikrosfärer täckas av poly (DL-lactide-co-glycolide) (PStarch microsphere is a dosage form suitable for the encapsulation of protein drugs. The starch microspheres investigated in this thesis are intended for release of the drug in a pre-designed way, or in controlled manner. For this purpose the starch microspheres can be coated by poly(DL-lactide-co-glycolide) (PLG) film, which is a release controlling. The term microsphere quality is complicated an
Ni-based superalloys, essential for high-temperature applications, derive strength from coherent second-order precipitates that impede dislocation motion through coherency misfit and elastic mismatch. This study employs multi-component phase-field crystal (PFC) simulations to explore the elastic deformation of such precipitates. Using a binary ordered square structure for the precipitate and a sin
In this article, we show evidence for the assembly of ordered 3-dimensional aggregates of 5-nm gold particles in toluene, 1-octanol, n-decane, and chloroform. The use of plunge-freezing allows to freeze the solution containing the aggregates at a rate which does not allow reorganisation of the particles during sample preparation. The samples were then observed using cryo-transmission electron micr
Sweden went back to gold at the pre‐war parity, whereas Finland returned at the existing rate, accepting the depreciation of the markka that had occurred over the war and early post‐war years. The authors use a quantity‐theory framework to investigate the results of the divergent exchange rate and monetary policies followed by the two countries. The Swedish economy was forced to undergo a severe c
Background: The Online Remote Behavioral Intervention for Tics (ORBIT) study was a multicenter randomized controlled trial of a complex intervention that consisted of a web-based behavioral intervention for children and young people with tic disorders. In the first part of a two-stage process evaluation, we conducted a mixed methods study exploring the reach, dose, and fidelity of the intervention
[K+(2,2,2-crypt)] Ge-2(9)2- containing the deltahedral Zintl anion Ge-9(2-) has been isolated from a solution of K4Ge9 in ethylenediamine in the presence of 2,2,2-crypt, intended as an intermediate in mixed-cluster synthesis. The subsequent crystallographic characterisation shows the closo-Ge-9(2-) cluster unit to be tricapped trigonal-prismatic with a symmetry very close to D-3h. Each Ge-9(2-) un
Introduction: The risks of preterm birth are known. We investigated the perinatal and infant mortality and morbidity after iatrogenic or spontaneous onset of extremely preterm birth. Material and methods: The present study used data from the population-based EXPRESS study comprising all infants delivered before 27+0 gestational weeks in Sweden between 2004 and 2007. All fetuses alive at admission
The tendency to buy expensive and unnecessary goods is a pattern of consumer behavior that is becoming all too common in our society. We consume luxury items to satisfy practical needs that are already satisfied in the quest toward self-fulfillment, or simply to impress those around us. The phenomenon of “status consumption” has become increasingly evident in modern society. Although conspicuous c
The arrival of new genetic technologies that allow efficient examination of the whole human genome (microarray, next-generation sequencing) will impact upon both laboratories (cytogenetic and molecular genetics in the first instance) and clinical/medical genetic services. The interpretation of analytical results in terms of their clinical relevance and the predicted health status poses a challenge
