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OBJECTIVES: The platelet ADP P2Y(12) receptor which is a target for the antithrombotic drug clopidogrel is also distributed on vascular smooth muscle cells and stimulate contraction. This study investigates whether AZD6140, in contrast to clopidogrel, can inhibit ADP-mediated arterial contractions. METHODS: Mice were treated with clopidogrel, 50 mg/kg, 24 and 2 h before experiment. Thoracic aorta

The subjects of this article are Kozhevnikov and Chistovitch's finding regarding the constancy of relative syllable durations and the inconstancy of relative speech sound durations for different rates of speech, and their proposal that vowels are elided because the necessary minimum duration of a consonant consumes all the time that happens to have been assigned to the syllable. The relative cons

If anyone begins to think about the term ultrasound, the first thing that comes to the mind is the fact that it is used in animal communications (e.g., bat navigation and dog whistles). Also, one may start to think that this term is familiar in daily life and has been used many times in medicine applications for foetal imaging, (SONAR). However, many questions come to the mind, such as, what is ha

Understanding the interaction between electromagnetic waves and matter is vital in applications ranging from classical optics to antenna theory. This paper derives physical limitations on the scattering of electromagnetic vector spherical waves. The assumptions made are that the heterogeneous scatterer is passive, and has constitutive relations which are on convolution form in the time domain and

This article explores the holistic approach to Leo Hurwitz's documentary aesthetic, by looking at how "Dialogue with a Woman Departed" (1981) interweaves the portrait of an individual with the contemporary history of the American nation and with the cyclical processes of nature.

Scand J Caring Sci; 2009 Being in charge of life: perceptions of lifestyle among women of retirement ageAim: The aim of this study was to describe the perceptions of lifestyle among women of retirement age. Background: Women go through many transitions during their lives, which impact on their lifestyle and possibly their outlook on life. Family circumstances such as motherhood and marital status

In this paper, new physical limitations on the extinction cross section and broadband scattering are investigated. A measure of broadband scattering in terms of the integrated extinction is derived for a large class of scatterers based on the holomorphic properties of the forward scattering dyadic. Closed-form expressions of the integrated extinction are given for the homogeneous ellipsoids, and t

Context: There are limited reliable epidemiological data concerning whether individuals with benign/malignant parathyroid tumor are at an elevated risk of developing nonendocrine malignancies or vice versa. Objective: The objective of the study was to quantify these risks, especially risk of parathyroid tumors after other cancers. Design: This was a population-based retrospective cohort study. Par

Environmental problems and technical systems in the society are fundamentally related to hydrology. Hydrology is a very comprehensive concept. In fact, there are at least ten independent disciplines within hydrology. Classical hydrology is a descriptive science with the water balance equation as almost the only means of quantifying computations. Hydrodynamics have now to some extent been introduce

The main objective of the paper is to briefly describe and exemplify some of the work that has been carried out within the STAMP project at IEA at Lund Institute of Technology within the field of mathematical modeling of wastewater treatment (WWT) processes. Three main areas have been identified - reduced-order models of the activated sludge process, modelling of biofilm processes including some e

The objective of this study was to provide data for the design of multi-nozzle impactors giving size-fractionated samples for X-ray emission analysis and for size-distribution determinations of the α-particle activity from aerosol-particle-attached radon progenies. Different multi-nozzle impactors with laser-drilled 50–60 μm diameter nozzles designed for a cut-off diameter of about 0.05 μm were ex

In this study, tactile sensitivity of gloved hand in the cold operation has been investigated. The relations among physical properties of protective gloves and hand tactile sensitivity and cold protection were also analysed both objectively and subjectively. Subjects with various gloves participated in the experimental study during cold exposure at different ambient temperatures of -12°C and -25°C

BACKGROUND: Intestinal ischemia and reperfusion (I/R) injury is a pivotal mechanism in critical illness and in the development of multiple organ dysfunction syndrome, in which the nuclear factor kappa B (NF-κB) activation plays a central role. Intestinal I/R injury initiates the extrinsic tissue factor or factor VIIa-dependent pathway of coagulation, also of importance in multiple organ dysfuncti

BACKGROUND: Overweight children show different movement patterns during walking than normal-weight children, suggesting the accuracy of multisensory activity monitors may differ in these groups. METHODS: Eleven normal and 15 high BMI African American children walked at 2, 4, 5, and 6 km/h on a treadmill wearing the Intelligent Device for Energy Expenditure and Activity (IDEEA) and SenseWear (SW)