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BACKGROUND. Neoantigen-driven recognition and T cell–mediated killing contribute to tumor clearance following adoptive cell therapy (ACT) with tumor-infiltrating lymphocytes (TILs). Yet how diversity, frequency, and persistence of expanded neoepitope-specific CD8+ T cells derived from TIL infusion products affect patient outcome is not fully determined. METHODS. Using barcoded pMHC multimers, we p
In 2023, the first edition of the diachronic-contemporary Swedish Academy Dictionary (SAOB) was finished after more than 130 years of work. The dictionary contains over 500,000 entries and describes the Swedish language from the 1520s to the present day. However, a consequence of the extended time of publication is that a significant part of the content, in particular in the first volumes, was out
The genetics of β-cell function (BCF) offer valuable insights into the aetiology of type 2 diabetes (T2D)1,2. Previous studies have expanded the catalogue of BCF genetic associations through candidate gene studies3–7, large-scale genome-wide association studies (GWAS) of fasting BCF8,9 or functional islet studies on T2D risk variants10–14. Nonetheless, GWAS focused on BCF traits derived from oral
Forests are pivotal for biodiversity, food webs, and human economies, and as carbon sinks their climate change mitigation potential is undisputed. However, whether trees continue to efficiently accumulate biomass at an increasing rate with age, how growth trajectories respond to climate change, and vary with latitude at species range margins is under debate. Here, we combine tree-ring data with bi
Soil cadmium (Cd) contamination significantly threatens ecosystems and human health. Traditional geochemical investigation, although accurate, is impractical for wide-area and frequent monitoring applications. Multi-spectral satellite images combined with the homologous pollution information (HPI) and the spectral and content information of soil organic matter (SOMSCI) is an unconventional and pro
The envisioning of a Scandinavian Theme Park to be located outside Malmö, close to the anchor of the bridge to Copenhagen, is here discussed in relation to the culture and heritage that was represented in the design proposals. The public presentations of the project were directed by a small group of visionaries who were given space and economic support by the political leadership of Malmö City, in
BackgroundPreliminary results from the SNAP trial presented at ESCMID Global 2025 reported a high incidence (19.8%) of acute kidney injury (AKI) in patients treated with (flu)cloxacillin for Staphylococcus aureus bacteraemia (SAB).ObjectiveIn Sweden, cloxacillin is used at lower daily doses, and the risk of nephrotoxicity has not been assessed in this setting.MethodsWe retrospectively evaluated re
High-density lipoproteins (HDLs) are responsible for removing cholesterol from arterial walls, through a process known as reverse cholesterol transport. The main protein in HDL, apolipoprotein A-I (ApoA-I), is essential to this process, and changes in its sequence significantly alter HDL structure and functions. ApoA-I amyloidogenic variants, associated with a particular hereditary degenerative di
This study explores the variability in nutritional composition of spinach at different maturity stages and assesses the effects of fermentation on reducing oxalates and enhancing minerals bioaccessibility. Spinach harvested at the age of 4th to 6th weeks was processed as raw, blanched, and fermented to develop freeze-dried powders. The growth stages of spinach from the 4th to the 6th week showed a
ObjectivesTo study if active sun exposure among women affects the risk of developing GCA or PMR in a prospective cohort study with restricted latitudinal variability.MethodsWe linked the response to questions relating to sun exposure from the Melanoma Inquiry in Southern Sweden (MISS) prospective cohort study in women to the risk of developing GCA or PMR. Healthcare data were gathered from the Skå
Pretend play is usually defined as an activity wherein objects and actions (but also 7 affective expression, at times) are separated from their original meanings. Its developmental 8 appearance is set around the second year of life, and increases dramatically in duration, 9 frequency and quality when play episodes start becoming more complex, both linguistically 10 and interactionally reaching its
To describe trends and identify maternal and pregnancy predictive risk factors for having a compensated claim for a maternal injury during delivery, as a proxy for having received suboptimal care. This nationwide retrospective cohort study included 1 754 869 births in Sweden between 2000 and 2016, including 4488 maternal injury claims filed with The National Swedish Patient Insurance Company (Löf)
An accurate estimation of evapotranspiration (ET) is vital for understanding the global hydrological cycle. However, large uncertainties in the present global ET products originate from the distinct model structures, assumptions, and inputs. The maximum entropy production (MEP) model provides a novel method for modeling ET based on parsimonious inputs and energy conservation. In this study, an R p
Context: Rapid growth has been suggested to promote islet autoimmunity and progression to type 1 diabetes (T1D). Childhood growth has not been analyzed separately from the infant growth period in most previous studies, but it may have distinct features due to differences between the stages of development. Objective: We aimed to analyze the association of childhood growth with development of islet
The WHO/UNICEF Joint Monitoring Program (JMP) for Water Supply, Sanitation and Hygiene (WASH) produces global estimates of the real situation of access to water, sanitation and hygiene services, and sanitation and hygiene in households, educational institutes and health care facilities; however it is lacking data on schools in Kazakhstan. Thus, the aim of this research was to assess access to WASH
This study’s purpose was to examine how 3 female managers subjectively thought about and related to femininity in relation to their leadership role. The emphasis was put on how the respondent viewed perceptions about leadership as a socially constructed concept, upon gender norms and a traditionally masculine leadership stereotype, and if, and how, they themselves consider this to have affected th
CAPACITY BUILDING PROGRAMME AGENDA 2030 AT LUND UNIVERSITY LAND IS LIFE The capacity building programme ‘Land is Life’ aims to build capacities and skills to strengthen the operational understanding of the synergies and trade-offs associated with SDG 15 – Life on Land. Land is at the heart of what makes agriculture function in sub-Saharan Africa, and as such it is also crucial to reducing poverty.
https://www.lucsus.lu.se/sites/lucsus.lu.se/files/land_is_life_information_and_application.pdf - 2026-07-11
I LUNDS UNIVERS ITBT Wind Energy in Ireland - An analysis of possibilities and constraints Michael Houlihan 167 Upper Salthill, Galway Ireland ++35391 586414 mike@scandinavica.com Submitted in part fulfilment for the Degree of Masters in Environmental Science Supervisor: Per Svenningsson, Department of Environment and Energy Systems Studies, Lund University, Sweden ++46 46 222 84 59 Per.Svenningss
https://www.lumes.lu.se/sites/lumes.lu.se/files/houlihan_michael.pdf - 2026-07-11
