Filetype
Increasingly, buildings are becoming complex “systems of systems” with many materials and attributes combining to create a whole that aims to meet a variety of design objectives including but not limited to functionality, aesthetic appeal, sustainability, safety, and security. We are now seeing this complexity move from commercial buildings and iconic structures to encompass even the residential s
O-Methylation of L-dopa was investigated as a possible regulatory mechanism in melanin metabolism. The methylation product of L-dopa, 3-O-methoxytyrosine was detected in extracts of cultured human melanocytes. The enzyme catechol-O-methyltransferase is responsible for this O-methylation and that of the dihydroxyindolic intermediates of melanogenesis. The enzyme is present in melanocytes in its sol
Arctic cyclones, as a prevalent feature in the coupled dynamics of the Arctic climate system, have large impacts on the atmospheric transport of heat and moisture and deformation and drifting of sea ice. Previous studies based on historical and future simulations with climate models suggest that Arctic cyclogenesis is affected by the Arctic amplification of global warming, for instance, a growing
Measuring innovation is a challenging but essential task to improve business performance. To tackle this task, key performance indicators (KPIs) can be used to measure and monitor innovation. The objective of this study is to explore how KPIs, designed for measuring innovation, are used in practice. To achieve this objective, the author draws upon literature on business performance in accounting a
BACKGROUND: Although coronary events (CE) and ischemic stroke share many risk factors, there are also some important differences. The aim of this paper was to assess the association of risk factors in relation to incident CE and ischemic stroke and to evaluate the heterogeneity in patterns of risk factors between the two outcomes.METHOD: Traditional risk factors and inflammatory markers associated
To ensure reliability and service availability, nextgeneration networks are expected to rely on automated anomaly detection systems powered by advanced machine learning methods with the capability of handling multi-dimensional data. Such multi-dimensional, heterogeneous data occurs mostly in todays Industrial Internet of Things (IIoT), where real-time detection of anomalies is critical to prevent
In this paper, I discuss resistance against antisemitism in relation to the overall antiracist struggle. Inspired by postcolonial theory and critical race studies, and by locating notions of “Swedishness” at the core of the analysis, I show that antisemitism can be understood as a form of structural racism entangled with other racisms. Through in-depth interviews with self-identified Jews in Swede
Heavy metal (HM) pollution remains a pressing global concern, affecting soil regarding food safety, and negatively influencing the UN Sustainable Development Goals (SDGs). We investigated the efficacy of untreated cypress biochar (UCB) and Ca-modified cypress biochar (MCB) in mitigating HM contamination and enhancing growth across native and contaminated soils (40 mg/kg) in carrot pot experiments.
Vapor–solid–solid (VSS) growth of III-V semiconductor nanowires (NWs) has long been considered an alternative for the vapor–liquid–solid (VLS) growth mode, with the potential to avoid the incorporation of deep-level impurities into semiconductors and to form compositionally abrupt interfaces. Most research however indicates that VSS growth has a much lower growth rate than observed in the VLS grow
Aims: Type 2 diabetes (T2D) patients with a clinical phenotype characterized by a high degree of insulin resistance are at increased risk of chronic kidney disease (CKD). We previously demonstrated that the endothelin receptor antagonist (ERA) atrasentan reduced insulin resistance in T2D. In this study, we compared the effect of atrasentan on insulin resistance across different phenotypic clusters
Background Adolescence is characterized by large bodily changes and a heightened body-focus. It is also a sensitive period for the onset of various forms of psychopathology. Previous longitudinal studies have shown that body dissatisfaction is a predictor of disordered eating, non-suicidal self-injury (NSSI), and depression among adolescents. Body dissatisfaction, however, only represents one aspe
This handbook brings together a collection of seminal research on the Sustainable Development Goals (SDGs) and investigates the effectiveness of the 17 goals for achieving transformative change toward sustainable development.As a collection of inter- and transdisciplinary research from around the world, this volume explores the applications, implications, and best practices of the goals at thematiWhen the world committed to end poverty and hunger as part of the Sustainable Development Goals (SDGs), the promise to “leave no one behind” was recognized as both an ethical responsibility and a key criteria for success. How can we make sure that such a promise becomes a reality, and what challenges lie ahead? This chapter aims to address these issues by focusing on parts of the world that, despi
Numerous neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis share a neuropathological hallmark: aberrant protein aggregation in the CNS. Microglia, the brain's innate immune cells, also play a pivotal role in the pathogenesis of these disorders. Multiple studies indicate that these pathological aggregates can propagate throughout the brain
Poly (ethylene-co-vinyl acetate) (EVA)/clay nanocomposites containing two different organoclays with different clay loadings were prepared. The transport of gases (oxygen and nitrogen) through the composite membranes was investigated and the results were compared. These studies revealed that the incorporation of nanoclays in the polymer increased the efficiency of the membranes toward barrier prop
Selective TDP-43 overexpression in oxytocin neurons in the paraventricular nucleus of the hypothalamus causes a decrease in oxytocin-immunopositive cells compared to uninjected mice. AAV-mediated TDP-43 overexpression in oxytocin neurons does not appear to be a major driver of behavioural and metabolic phenotypes in mice.
AIMS: A history of preeclampsia is associated with at least a twofold increased risk of coronary artery disease (CAD), with unclear underlying mechanisms. This study aimed to investigate coronary plaque characteristics in women with a history of preeclampsia compared to women from the general population.METHODS: In this cross-sectional study, women with a history of preeclampsia from the Cardiovas
Introduction: Vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) is a technique combining vaginal entrance to the abdomen with endoscopic overview. Previous studies have shown that vNOTES decreases operating time, hospitalization, postoperative complications, and pain. We aimed to present patient demographics, costs, and surgical outcomes following the implementation of vNOTES for be
Out-of-pocket (OOP) expenditures for childbirth in Bangladesh have increased substantially, intensifying financial pressure on lower-income households. While wealthier groups historically bore higher delivery costs, recent trends indicate a narrowing gap in spending across socioeconomic strata. This study investigates the drivers of this convergence in delivery-related expenditures between 2014 an
The Colombian Peace Agreement signed in 2016 was saluted internationally by scholars, policy makers and practitioners for encompassing the concept of territorial peace as a means of ensuring local participation in the strengthening of state institutions. Based on engaged research conducted in the Department of Cauca and Bogotá between 2017 and 2020, we critically analyse territorial peace, explori
