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När immunterapi mot allergi inte fungerar – Vetenskap och Hälsa

När immunterapi mot allergi inte fungerar – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök När immunterapi mot allergi inte fungerar 2025-04-14 Det blir allt vanligare att utveckla pollenallergi, allergisk rinit. Nu tittar forskare vid Lunds universitet närmare på effekten av allergen immun

https://www.vetenskaphalsa.se/nar-immunterapi-mot-allergi-inte-fungerar/ - 2026-06-01

barn – Vetenskap och Hälsa

barn – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Etikett: barn Samband mellan mycket hög PFAS-exponering och astma hos barn 2026-04-22 Forskare vid Lunds universitet har undersökt samband mellan exponering för PFAS och utveckling av astma. Resultaten visar att bland de barn vars mammor

https://www.vetenskaphalsa.se/tag/barn-2/ - 2026-06-01

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SELECTED ASPECTS OF THE 2013 ZIMBABWEAN CONSTITUTION AND THE DECLARATION OF RIGHTS Edited by Admark Moyo 1 Selected Aspects of the 2013 Zimbabwean Constitution and the Declaration of Rights Edited by Admark Moyo 2 The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the Raoul Wallenberg Institute of

https://rwi.lu.se/wp-content/uploads/2021/04/Selected-Aspects-of-2013-Zimbabwean-Constitution-and-the-DoR.pdf - 2026-06-02

Higher levels of the soluble receptor for advanced glycation end products and lower levels of the extracellular newly identified receptor for advanced glycation end products were associated with lipid-lowering drugs in patients with type 1 diabetes : a comparative cross-sectional study

Background: The receptors for advanced glycation end products (RAGE) are increased in atherosclerotic plaques. Soluble (s)RAGE decreases, whereas the extracellular newly identified receptor for advanced glycation end products (EN-RAGE) increases inflammatory responses mediated by RAGE. The aims were to explore whether sRAGE, EN-RAGE and the EN-RAGE/sRAGE ratio, were associated with the use of lipi

Extracellular matrix in atherosclerotic plaques: its role in plaque stability

Atherosclerosis is a systemic disease affecting the large arteries caused by the accumulation of lipids in the vessel wall. Cardiovascular disease due to atherosclerosis is today the most common cause of death globally through its end consequences: myocardial infarctions and stroke. The extracellular matrix (ECM) is a network of structural fibrous proteins, proteoglycans and glycoproteins. ECM pro

GNAS gene is an important regulator of insulin secretory capacity in pancreatic β-cells

BACKGROUND: Type 2 diabetes (T2D) is a complex polygenic disease with unclear mechanism. In an attempt to identify novel genes involved in β-cell function, we harness a bioinformatics method called Loss-of-function tool (LoFtool) gene score. METHODS: RNA-sequencing data from human islets were used to cross-reference genes within the 1st quartile of most intolerant LoFtool score with the 100th most

Effects of lactobacillus plantarum and lactobacillus paracasei on the peripheral immune response in children with celiac disease autoimmunity : A randomized, double-blind, placebo-controlled clinical trial

Two Lactobacillus strains have proven anti-inflammatory properties by reducing pro-inflammatory responses to antigens. This randomized double-blind placebo-controlled trial tested the hypothesis that L. plantarum HEAL9 and L. paracasei 8700:2 suppress ongoing celiac disease autoimmunity in genetically at risk children on a gluten-containing diet in a longitudinally screening study for celiac disea

Dementia Risk According to Indices of Insulin Sensitivity and Beta-Cell Function in Individuals With Newly Diagnosed Type 2 Diabetes : A Cohort Study

Background: Insulin resistance and impaired insulin secretion are hallmarks of type 2 diabetes (T2D) and may influence risks of complications including dementia. We investigated dementia risk across T2D subgroups defined by beta-cell function and insulin sensitivity. Methods: We used Homeostasis Model Assessment-2 indices of beta-cell function (HOMA2-B) and insulin sensitivity (HOMA2-S) to classif

Effect of pH on niacinamide skin permeation

Niacinamide (NIA) is a widely used skincare ingredient with established benefits for skin barrier support, inflammation reduction, and dermal health. However, the mechanisms governing its transdermal delivery remain insufficiently understood, particularly regarding how formulation pH influences its permeation through the stratum corneum (SC). This study investigates how donor phase pH (5.0 vs. 7.4

Cognitive impairment in medical inpatients

Popular Abstract in Swedish Befolkningsutvecklingen i Sverige medför att allt fler människor blir äldre. Detta är ett positivt resultat till följd av att befolkningen är vid bättre hälsa. Dock innebär det att fler människor kommer att uppnå en ålder där multisjuklighet (att ha flera kroniska sjukdomar samtidigt), oförmåga att klara sig själv och kognitiv svikt är vanligt förekommande. Detta kommerBackground: People aged over 80 years is the most rapidly growing segment of the population in Sweden. This group is susceptible to multimorbidity, disability and cognitive impairment. Managing these issues will be essential in order to obtain a sustainable healthcare system in the near future. Aim: To determine if increased acknowledgement of cognitive impairment could improve healthcare for el

Stamcelltransplantation – nyckeln till ett friskare åldrande?

Genom att frysa ner egna friska blodstamceller i 20-årsåldern, tina upp dem och göra en stamcellstransplantation i 40–50-årsåldern skulle det vara möjligt att föryngra sitt blodbildande system och sitt immunförsvar. Science fiction? Det fungerar i alla fall när gamla möss får nya friska blodstamceller från unga möss.   Möss blir bara ett par år gamla som mest. Det gör det smidigt att använda möss

https://www.medicin.lu.se/forskning/vad-forskar-du-om/stamcelltransplantation-nyckeln-till-ett-friskare-aldrande - 2026-06-02

Social media and connective action: The case of the Saudi women’s movement for the right to drive

This article explored the use of social media and mobile communication by women in Saudi Arabia who campaigned for the right to drive from 1990. Due to the globally unique ban on women driving in the Kingdom, females always needed a male driver to transport them. The Saudi government announced in September 2017 that women would be allowed to drive from June 2018. Using the theory of connective act

Non-targeted analysis strategy for the identification of phenolic compounds in complex technical lignin samples

Lignin is the second most abundant biopolymer in nature and a promising renewable resource for aromatic chemicals. For the understanding of different lignin isolation and conversion processes, the identification of phenolic compounds is of importance. However, due to the vast number of possible chemical transformations, the prediction of produced phenolic structures is challenging, and a non-targe

Recent advances in the analysis of vitamin D and its metabolites in food matrices

Vitamin D and its analogues are fat-soluble vitamins that carry out important functions in human and animal organisms. Many studies have pointed out the relationship between the deficiency of these substances and the development of both skeletal-and extra-skeletal diseases. Although vitamin D is fundamentally derived from the bio-transformation of its precursor, 7-dehydrocholesterol, through the a

Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets.

AIMS/HYPOTHESIS: To date, the molecular function of most of the reported type 2 diabetes-associated loci remains unknown. The introduction or removal of cytosine-phosphate-guanine (CpG) dinucleotides, which are possible sites of DNA methylation, has been suggested as a potential mechanism through which single-nucleotide polymorphisms (SNPs) can affect gene function via epigenetics. The aim of this

Maternal smoking during pregnancy and offspring type 1 diabetes mellitus risk: accounting for HLA haplotype.

The main objective of this study was to investigate the risk of type 1 diabetes mellitus (T1D) in children exposed to tobacco smoking in utero, also taking genetic predisposition as expressed by HLA haplotype into account. In Skåne, the southernmost county of Sweden, all children born 1999-2005 who developed T1D were registered, resulting in 344 cases. For each child with T1D, three control childr

S100A8 and S100A9: DAMPs at the crossroads between innate immunity, traditional risk factors, and cardiovascular disease.

Amplification of innate immune responses by endogenous danger-associated molecular patterns (DAMPs) promotes inflammation. The involvement of S100A8 and S100A9, DAMPs belonging to the S100 calgranulin family, in the pathogenesis of cardiovascular disease is attracting an increasing amount of interest. S100A8 and S100A9 (also termed MRP8 and MRP14) preferentially form the S100A8/A9 heterodimer (MRP