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Over 50 million people worldwide have epilepsy. In nearly 30% of these cases, epilepsy remains unsatisfactorily controlled despite the availability of over 20 antiepileptic drugs. Moreover, no treatments exist to prevent the development of epilepsy in those at risk, despite an increasing understanding of the underlying molecular and cellular pathways. One of the major factors that have impeded rap

The shell structure of low-lying neutron resonance levels in axially symmetric quadrupole-deformed potentials is discussed, which seems analogous to that of weakly bound neutrons. As numerical examples, nuclei slightly outside the neutron drip line, Mg271239 and C15621, are studied. For the lowest resonance I obtain Iπ=Ωπ=5/2- for Mg39 which is likely to be prolately deformed, while Iπ=Ωπ=1/2+ may

According to virtually all international corruption rankings, Sweden is one of the top performing countries with very few exposed incidents of corruption. But does this automatically imply that it can be declared a perfectly ‘healthy patient’? By extensively reviewing existing research and adding empirical sets of data, the authors of A Clean House? shed light on shady corners of the Swedish case.

Many observed giant planets lie on eccentric orbits. Such orbits could be the result of strong scatterings with other giant planets. The same dynamical instability that produces giant planet scatterings can also alter the orbits of terrestrial planets. For example, a habitable rocky planet in the system can be ejected or transported to an orbit outside the habitable zone. Therefore, there is a lin

In some high-profile Swedish cases on violence in intimate relationships, policemen and judges have been blamed for missing important aspects of the victim’s vulnerable situation and the ongoing violence, and indirectly causing the death of the women victims. When these types of cases encounter the criminal justice system, two seemingly opposites are confronted: autonomy and vulnerability. In dete

As in the rat, gastrin and an extract of the acid-producing part of the stomach (proventriculus) were found to lower the blood Ca2+ concentration in the chicken. Furthermore, gastrin enhanced the uptake of 45Ca into the femur. It has been suggested previously that gastrin causes hypocalcemia in the rat by releasing gastrocalcin, a hypothetical hormone thought to reside in the acid-producing part o

We examined the effects of physical training in 10 predialytic uremic patients (7 men, 3 women, mean age 47 ± 8 years) with an average glomerular filtration (GFR) of 15 ± 7 ml/min x 1.73 m2. All 10 patients participated in an exercise programme 3 times/week for 3 months and were compared to a control group of 9 patients with comparable baseline variables. The exercise group increased its maximal e

Financial investment behavior is highly correlated between parents and their children. Using Swedish data, we find that the decision of adoptees to hold equities is associated with the behavior of both biological and adoptive parents, implying a role for both genetic and environmental influences. However, we find that nurture has a stronger influence on the share of financial assets invested in eq

Study Question Do sonographic characteristics of ovarian endometriomas vary with age in premenopausal women? Summary Answer With increasing age, multilocular cysts and cysts with papillations and other solid components become more common whereas ground glass echogenicity of cyst fluid becomes less common. What is Known Already Expectant or medical management of women with endometriomas is now acce

What are the underlying motivations for the conceptualization of events? Recent studies show that when people are asked to use nonverbal gestures to describe transitive events they prefer the semantic order Agent-Patient-Act, analogous to SOV in grammatical terms. The original explanation has been that this pattern reflects a cognitively “natural order” for the conceptualization of events. However

Fear of falling (FOF) is common in persons with Parkinson’s disease (PD) and may have large consequences in daily life, causing a sedentary lifestyle, social isolation and reduced quality of life. FOF is therefore an important aspect to consider for researchers as well as clinicians and the rehabilitation team. Adequate and high quality rating scales are needed to be able to accurately assess FOF

The protein product of the deleted in colorectal cancer (DCC) gene possesses netrin-binding activity and may be involved in axonal guidance during retinal development. The temporal and spatial expression of DCC was analyzed in developing rat retina by means of immunoblotting and immunohistochemistry as well as by reverse transcription-polymerase chain reaction. Transient DCC protein expression is

BACKGROUND: Myelodysplastic syndromes are clinically heterogeneous disorders characterized by clonal hematopoiesis, impaired differentiation, peripheral-blood cytopenias, and a risk of progression to acute myeloid leukemia. Somatic mutations may influence the clinical phenotype but are not included in current prognostic scoring systems.METHODS: We used a combination of genomic approaches, includin

During the 90ies, ISO TC92 SC1 started the development of full-scale tests for facades based upon an international review. The work resulted in two standards namely ISO 13785 part 1 and part 2. The work was performed in WG7 and a substantial input from international experts was given. The paper gives a short historical update on the development but also includes a short overview of the major type

Based on a review of studies of functional and comparative anatomy of crustacean eyes, a hypothesis is formed on eyes in primitive crustaceans. It is suggested that they were similar to present-day frontal eyes of the malacostracan type. Neuronal architecture suggests that the development to apposition compound eye followed two main routes, one seen in malacostracansand the other in non-malacostra