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BACKGROUND/AIM: High morbidity and mortality rates, chronic course of disease and numerous clinical complications, make diabetes mellitus (DM) type 2 bear significant financial burden for healthcare system of Serbia. The aim of this study was to compare true disease-related expenses measured in the random sample of patients originating from the Central Serbia in 2007 and national estimate of total
Objective: To examine cause-specific mortality beyond cardiovascular diseases (CVDs) in patients with gout compared to the general population. Methods: We included all residents of Skåne (Sweden) age ≥18 years in the year 2002. Using the Skåne Healthcare Register, we identified subjects with a new diagnosis of gout (2003–2013) and matched each person with gout with 10 comparators free of gout, by
Behandling av patienter med alkohol- eller drogberoende är en komplex flerstegsprocess som behandlar både substansberoende och co-morbiditeter. Riskfyllda livsstilar, inklusive tobaksrökning, otillräcklig fysisk aktivitet och ohälsosam kost, som kan förvärra hälsotillståndet och själva beroendebehandlingen, är mycket vanligt bland dessa patienter. Det komplexa hälsofrämjande programmet (Very IntegTreatment of patients with alcohol or drug use disorders is a complex multistage process addressing the substance addiction and co-morbidities. The risky lifestyles, including tobacco smoking, insufficient physical activity and unhealthy diet, which can aggravate health condition as well as addiction treatment itself, are very common among these patients. The complex health promotion (Very Integra
There is a scarcity of instruments for assessing opportunities for residentswith psychiatric disabilities to engage in meaningful home-based activities.We thus developed the Perceived Meaning of Activity in Housing (PMA-H),containing four subscales (activity opportunities, social interaction, developingas a person, and organization and planning). The aim of the study was to investigate the content
Detta kapitel handlar om en grupp barn som fick sina första erfarenheter av samhällsvård i 0-4-årsåldern. Därefter har de en varierande placeringshistoria under barndomen (0-18 år). De har följts upp vid åtta olika tillfällen under barndom och vuxenliv. Detta kapitel fokuserar på hur de hade det i 25-30-årsåldern samt i 35-39-årsåldern, eftersom det är glest med uppföljningar av barn med erfaren
Electrical field stimulation (EFS) of the rabbit urethral lamina propria elicited a frequency‐dependent non‐adrenergic, non‐cholinergic (NANC) relaxation, which was abolished by NΩ–nitro‐L‐arginine (l‐NOARG). Ω‐Conotoxin GVIA, a selective blocker of N‐type voltage‐operated calcium channels (VOCCs), and Ω‐conotoxin MVIIC (blocker of N‐ and Q‐type VOCCs) inhibited the NANC relaxation, and the inhibi
Scarcity of in situ measurements of greenhouse gas (GHG) fluxes hamper calibration and validation of continental assessments of carbon budgets in Africa. It limits essential studies of ecosystem functioning and ecosystem processes. Wide reported ranges of estimated African net primary production (NPP) and gross primary production (GPP) is a function of the uncertainty originating from this scarcit
Using a dislocation simulation approach, the basic equation for a crack perpendicular to a bimaterial interface is formulated in this paper. A novel expansion method is proposed for solving the problem. The complete solution for the problem, including the T stress ahead of the crack tip and the stress intensity factors are presented. The stress field characteristics are analyzed in detail. It is f
Open Innovation (OI) has attracted scholarly interest from a wide range of disciplines since introduced by Chesbrough, i.e. ”a paradigm that assumes that firms can and should use external ideas as well as internal ideas, and internal and external paths to market, as they look to advance their technology”. However, OI remains unexplored for software engineering (SE), although widespread in practice
Background: Late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) using magnitude inversion recovery (IR) or phase sensitive inversion recovery (PSIR) has become clinical standard for assessment of myocardial infarction (MI). However, there is no clinical standard for quantification of MI even though multiple methods have been proposed. Simple thresholds have yielded varying re
It has long been known that the three largest subunits in the membrane domain (NuoL, NuoM and NuoN) of complex I are homologous to each other, as well as to two subunits (MrpA and MrpD) from a Na+ /H+ antiporter, Mrp. MrpA and NuoL are more similar to each other and the same is true for MrpD and NuoN. This suggests a functional differentiation which was proven experimentally in a deletion strain m
The study of molecular dynamics involves observations of the motion of nuclei and electrons. While nuclear motion is usually on the picosecond or femtosecond timescale, attosecond precision is necessary to directly observe the motion of electrons. Ultrashort laser pulses have become established as a viable tool for probing femtosecond dynamics by irradiating the target for only extremely short tim
There is an increasing expectation from research funding bodies that projects in working life and policy research (and other fields) should demonstrate clear and demonstrable impacts on policy and practice. In turn, many also argue that impact, beyond scientific impact, can be leveraged by stakeholder engagement. But what do we mean by stakeholder engagement in the conduct of working life research?
Dissolved organic carbon (DOC) derived from plant litter plays an important role in the ecosystem carbon balance and soil biogeochemistry. However, in boreal coniferous forests no integrated understanding exists of how understory vegetation contributes to litter leaching of DOC, nitrogen (N) and phosphorus (P) with different bioavailability at the forest stand level. We characterized water extract
A test of CP invariance in Higgs boson production via vector-boson fusion is performed in the H→ττ decay channel. This test uses the Optimal Observable method and is carried out using 36.1fb−1 of s=13TeV proton–proton collision data collected by the ATLAS experiment at the LHC. Contributions from CP-violating interactions between the Higgs boson and electroweak gauge bosons are described by an eff
Vitamin D and its analogues are fat-soluble vitamins that carry out important functions in human and animal organisms. Many studies have pointed out the relationship between the deficiency of these substances and the development of both skeletal-and extra-skeletal diseases. Although vitamin D is fundamentally derived from the bio-transformation of its precursor, 7-dehydrocholesterol, through the a
The demands on library services are quickly changing in a continually updating digital age. This increases the importance of a good understanding of the needs and demands of the users. In order to sample and follow the change in user needs library organisations analyse their efforts using a series of different methods. In a recent survey distributed to all 301 European LIBER university libraries,
