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Scaling methodology represents a problem in assessments of activities of daily living (ADL) and little is known about how the results of these assessments are affected by data treatment principles and statistical methods. The aims of this paper are to: (i) describe alternative ways of transforming a response pattern on ADL into a single number; and (ii) to present and compare different ways of ana
Purpose: Alkaline sphingomyelinase (alk-SMase) is an enzyme that hydrolyses sphingomyelin in a bile salt-dependent manner in the gastrointestinal tract, and has been proposed as an inhibitor of colon carcinogenesis. Ursolic acid (UA) is a plant-derived pentacyclic triterpenoid that has been shown to have anti-proliferative and apoptotic effects on HT29 human colon adenocarcinoma cells, with activa
BACKGROUND: Gastrin stimulates uptake of Ca(2)+ into bone and causes transient hypocalcemia, possibly by releasing a peptide hormone from enterochromaffin-like (ECL) cells, which are histamine- and peptidehormone-producing cells in the acid-producing part of the stomach. However, if ECL cells secrete a calciotropic hormone, it is to be expected that their activity is affected by the serum Ca(2)+ c
Objectives: To systematically review measurement properties of visual assessment and rating of Postural Orientation Errors (POEs) in participants with or without lower extremity musculoskeletal disorders. Methods: A systematic review according to the PRISMA guidelines was conducted. The search was performed in Medline (Pubmed), CINAHL and EMBASE (OVID) databases until August 2016. Studies reportin
GDNF and the GDNF receptors, c-Ret, GFRα1 and 2 mRNA is expressed in the developing chicken retina. GDNF labelling was mainly found in embryonic day 4-5 retina but weak labelling could also be found over scattered retinal cells at later stages. c-ret labelling was found over ganglion cells, amacrine and horizontal cells; the preferred GDNF receptor (GFRα1) over amacrine and horizontal cells; and t
Animal flight represents a great challenge and model for biomimetic design efforts. Powered flight at low speeds requires not only appropriate lifting surfaces (wings) and actuator (engine), but also an advanced sensory control system to allow maneuvering in confined spaces, and take-off and landing. Millions of years of evolutionary tinkering has resulted in modern birds and bats, which are achie
Immune cell-derived cytotoxic pathways have been implicated in antitumor immune responses. The goal of this study is to characterize how these cytotoxic pathways influence ovarian cancer development. We have utilized the TgMISIIR-TAg transgenic mouse model which expresses the transforming SV40 TAg in the ovary, leading to spontaneous development of ovarian tumors that closely mimic human epithelia
This study assesses the effect of some extended Enterprise Resource Planning (ERP) capabilities (Collaboration, Analytics, Web-portals, Add-ons) and ERP use on ERP value. The research conducted, followed a mixed-methods approach using an exploratory study (Delphi) and the resource-based view of the firm to understand the ERP capabilities and develop three competing models surrounding these capabil
This study investigated how preschool children processed and understood critical information in Magical Garden, a teachable agent-based play-&-learn game targeting early math. We analyzed 36 children’s (ages 4–6 years) real-time behavior during game-use to explore whether children: (i) processed the information meant to support number sense development; (ii) showed an understanding of the teac
Physical exercise for patients treated with allogeneic haematopoietic stem cell transplantation (allo-HSCT) has shown positive effects on the quality of life and fatigue in experimental trials. However, there is a need for longitudinal evaluation of exercise programmes implemented in a real-world clinical setting. The aim of this prospective study was to evaluate the impact of an exercise programm
Background: Lesions of the Ampulla of Vater are a rare condition and represent <10% of peri-ampullary neoplasms. Nevertheless, ampullary adenomas have the potential for malignant transformation to ampullary carcinomas by an adenoma-to-carcinoma sequence. Thus, adequate patient selection and complete resection (R0) of non-invasive ampullary lesions either by endoscopic papillectomy (EP), surgical a
The UN Convention on the Rights of the Child is a human rights legal document decided and adopted by the UN General Assembly in November 1989. This international convention has had a major impact on children’s rights, policies and legislation in many countries around the world. Another prominent feature of the development, however, is the lack of research in many areas on implementation of childre
Expanding now familiar debates about the impact of the 'historical turn' upon the field of international law, this article considers some of the different ways in which 'turn to history' scholars have confronted the methodological and theoretical tensions arising from the central, yet paradoxical, role occupied by the sources doctrine in international law. We suggest that the anxiety over the sour
This book analyzes the exile ontology of Spanish philosopher María Zambrano (1904-1991). Karolina Enquist Källgren connects Zambrano’s lived exile and political engagement with the Spanish Civil War to her poetic reason, and argues that Zambrano developed a theory of expressive subjectivity that combined embodiment with the expressive creativity of the human mind. The analysis of recurring literar
The phylogeny of the Patagonian-Antarctic genus Himantormia is investigated with nuclear ITS rDNA sequences in PAUP. The monotypic genus Nimisia is synonymized with Himantormia, and the new combination H. deusta is proposed. The secondary chemistry was investigated using HPLC; protocetraric, stictic, succinprotocetraric and confumarprotocetraric acids were detected in H. deusta for the first time,
