Search results

Background: Fatigue is common among people with multiple sclerosis (MS), and significantly influences engagement in occupations. The Managing Fatigue (MF) programme is an evidence-based occupational therapy group-based intervention, utilising self-management science that provides people with tools to manage fatigue. Although the national MS-guidelines in Sweden cite this as best practice, a Swedis

Huntington’s disease is caused by a mutation in the gene that codes for the protein huntingtin (HTT). A therapeutic strategy for Huntington’s disease is to lower the levels of huntingtin in the brain. However, multiple clinical trials have been stopped due to adverse effects. This indicates that there is still a lot that we do not understand about huntingtin. Similarly to other neurodegenerative d

A new empirical method for in situ determination of the inventory of 137Cs in soil (ACs, kBq m−2) at grasslands and forests using a field-portable NaI(Tl) scintillation spectrometer-dosimeter was developed. The method is based on evaluation of the ambient dose equivalent build-up factor. The practical implementation of the new method with the spectrometer-dosimeter does not require a priori knowle

Rationale: Recovery after heart transplantation is challenging and many heart recipients struggle with various transplant-related symptoms, side-effects of immunosuppressive medications and mental challenges. Fatigue has been reported to be one of the most common and distressing symptoms after heart transplantation and might therefore constitute a barrier to self-efficacy, which acts as a moderato

The development of process parameters and scanning strategies for bulk metallic glass formation during additive manufacturing is time-consuming and costly. It typically involves trials with varying settings and destructive testing to evaluate the final phase structure of the experimental samples. In this study, we present an alternative method by modelling to predict the influence of the process p

Background: To assess whether retrograde cerebral perfusion reduces neurological injury and mortality in patients undergoing surgery for acute type A aortic dissection. Methods: Single-center, retrospective, observational study including all patients undergoing acute type A aortic dissection repair with deep hypothermic circulatory arrest between January 1998 and December 2022 with or without the

IFN-γproducing invariant NKT (iNKT)1 cells are lipid-reactive innate-like lymphocytes that are resident in the thymus and peripheral tissues where they protect against pathogenic infection. The thymic functions of iNKT1 cells are not fully elucidated, but subsets of thymic iNKT cells modulate CD8 T cell, dendritic cell, B cell, and thymic epithelial cell numbers or function. In this study, we show

Recent years has seen a number of music researchers taking interest in the concept of affordances. Although interpretation of the concept varies, a common denominator is that affordances are opportunities for actions emerging between a subject and the environment. As such, it is an analytical perspective that highlights material and embodied dynamics of musical practice, dimensions central to musi

Focusing on three initiatives of the United Nations Framework Convention on Climate Change (UNFCCC) Secretariat – the Momentum for Change Initiative, the Lima–Paris Action Agenda, and the Non-state Actor Zone for Climate Action – this chapter studies how an international environmental bureaucracy can evolve from a low-key and servant-like secretariat to an actor in its own right. It argues that in

Perceived fairness is a central determinant of acceptance or resistance toclimate policies. Resistance to climate policies is shaped by structural factors,including socio-economic conditions and cultural identities. But policy designaspects that are sensitive to perceptions of fairness can increase the public’sacceptance of the measures proposed. Overcoming resistance requires anunderstanding of t

Background: To date, studies investigating the association between pre-biologic biomarker levels and post-biologic outcomes have been limited to single biomarkers and assessment of biologic efficacy from structured clinical trials. Aim: To elucidate the associations of pre-biologic individual biomarker levels or their combinations with pre-to-post biologic changes in asthma outcomes in real-life.

We study supercooled first-order phase transitions above the QCD scale in a wide class of conformal Majoron-like U(1)′ models that explain the totality of active neutrino oscillation data and produce a detectable stochastic gravitational wave background (SGWB) at LIGO, LISA and ET. We place constraints on the U(1)′ breaking scale and gauge coupling using current LIGO-Virgo-Kagra data. We find that

Background: Long-term follow-up (LTFU) care, although endorsed, is not available for the majority of adult survivors of childhood, adolescence and young adult (CAYA) cancer. Barriers to implementation include lack of time, knowledge, personnel and funding. Sustainable solutions are urgently needed to address the needs of CAYA cancer survivors to improve the quality of life and reduce the burden of

The 400-km long coast of the Bight of Benin, formed by sand barriers and lagoons, is bordered to the east by the Niger River Delta and to the west by the Volta River Delta and is characterized by several coastal infrastructures, of which the most important are the deep water harbors of Lomé, Cotonou, and Lagos. In this study, an enhanced version of the CASCADE coastal evolution model was implement

INTRODUCTION: Antineoplastic drugs (ADs) are frequently used pharmaceuticals in the healthcare, and healthcare workers can be occupationally exposed to ADs. Monitoring of surface contamination is a common way to assess occupational exposure to ADs. The objective was to develop and validate a sensitive and quantitative monitoring method to determine surface contaminations of Pt as a marker for Pt-c