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Streptococcal M protein: a multipotent and powerful inducer of inflammation.
Med kroppen som instrument : en studie av new age med fokus på hälsa, kroppslighet och genus
Popular Abstract in Swedish I denna avhandling studeras new age utifrån problemområdena hälsa, kroppslighet och genus. Genom intervjuer med andliga sökare inom new age ges en bild av de trosföreställningar och attityder som kännetecknar rörelsen. Också sökarnas olika vägar till new age och relationer till andra religioner analyseras. I det senmoderna samhället är hälsa ett eftersträvansvärt livsväIn this thesis New Age is studied from a sociological perspective, with a focus on health, body, and gender. One purpose is to examine how people within New Age view and relate to these problem areas. A parallel purpose is to find explanations to why women predominantly take an interest in New Age, and to discover how these explanations are related to the view on health, body and gender. The subje
Interactions of the extracellular matrix proteoglycans decorin and biglycan with C1q and collectins
Decorin and biglycan are closely related abundant extracellular matrix proteoglycans that have been shown to bind to C1q. Given the overall structural similarities between C1q and mannose-binding lectin (MBL), the two key recognition molecules of the classical and the lectin complement pathways, respectively, we have examined functional consequences of the interaction of C1q and MBL with decorin a
St Gallen molecular subtypes in screening-detected and symptomatic breast cancer in a prospective cohort with long-term follow-up.
Diagnosis by screening mammography is considered an independent positive prognostic factor, although the data are not fully in agreement. The aim of the study was to explore whether the mode of detection (screening-detected versus symptomatic) adds prognostic information to the St Gallen molecular subtypes of primary breast cancer, in terms of 10-year cumulative breast cancer mortality (BCM).
Second order discourse: critically-informed research
Researchers who desire to bring about change in organizational settings require approaches to inquiry which can go beyond superficial appearances and prejudice. In seeking to go beyond mere examination of socio technical systems researchers have developed a proliferation of different approaches. Many of these have drawn upon social and human sciences to ground methods and assumptions in philosophi
Gaining competitive advantage through information technology. A resource-based approach to the creation and employment of strategic IT resources
Information technology is a central phenomenon in modern society. It is widely used in a variety of settings and commercial firms use it for a variety of purposes. It could be an Internet application, a manufacturing system, office support software, electronic data interchange or something else, applied in order to create economic benefits through improvements of operative work tasks and business
Looking for Echoes of Medieval Poetry in Arda’s Nature
On Categorizing the IS Research Literature: User Oriented Perspective
The purpose of this paper is to propose a new approach for categorizing the body of knowledge captured in the existing literature, past and present in such a way that contributions to the use side of systems development are made explicit. The new twist of this approach is that it seeks to bridge the most prevalent divides currently fragmenting the IS literature by offering an integrative classific
Letters, learning and Learned Ladies - An Analysis of Otto Sperling, Jr:s (1634-1715) correspondence with Scandinavian Women.
The paper offers an analysis of some aspects (pragmatic, status, personal, feminist and stylistic) of the letters exchanged between the Danish Profesor Otto Sperling, Jr, 1634-1715) and three learned women (Anne Margrethe Qvitzow, the Cille Gad and Sophia Elisabeth Brenner), differentiating between the personal elements and the more formal and image-building ones in order to create a basis for a d
The Role of Reactive Oxygen Species in Animal Models of Autoimmunity
Reactive oxygen species (ROS) produced by the phagocyte NADPH oxidase complex are important in the killing of invading pathogens. Lately, a role of ROS has been suggested in regulation of the immune system. This was further highlighted when the Ncf1 gene, encoding a subunit of the NADPH oxidase complex, was found to regulate arthritis severity in rats. Interestingly, the fact that increased arthri
Subject and generic skills in unity : information literacy in collaboration for enhanced learning
A Metalloproteinase Karilysin Present in the Majority of Tannerella forsythia Isolates Inhibits All Pathways of the Complement System.
Tannerella forsythia is a poorly studied pathogen despite being one of the main causes of periodontitis, which is an inflammatory disease of the supporting structures of the teeth. We found that despite being recognized by all complement pathways, T. forsythia is resistant to killing by human complement, which is present at up to 70% of serum concentration in gingival crevicular fluid. Incubation
Health education in Top Shape - governing and communication strategies in the edutainment series Top Shape
A Critical Evaluation of Inflammatory Markers in Huntington’s Disease Plasma
BACKGROUND: Huntington’s Disease (HD) is a hereditary, progressive neurodegenerative disorder characterised by both neurological and systemic symptoms. In HD, immune changes can be observed before the onset of overt clinical features raising the possibility that immune markers in plasma could be used to track disease progression. It has previously been demonstrated that a widespread, progressive i
The practice of language policy research
Older women and men with urinary symptoms.
The aim was to compare urinary symptoms and their influence on daily life among elderly (75+) women and men in a sample that previously had reported difficulties controlling urine (urine incontinence (UI)) and/or other urinary symptoms (OU). A further aim was to find underlying structures of urinary symptoms and to identify symptoms that had an impact on seeking medical help and need of help in da
Unaltered Size-selectivity of the Glomerular Filtration Barrier in Caveolin-1 Knock-out (KO) mice.
The transfer of albumin from blood to tissue has been found to be increased in caveolin-1 knock-out (KO) mice. This has been considered to reflect an increased microvascular permeability, conceivably caused by an increased endothelial production of nitric oxide (NO) in mice lacking caveolin-1. To investigate whether such an increase in endothelial NO-production would also affect the glomerular bar
Activation of TAFI on the Surface of Streptococcus pyogenes Evokes Inflammatory Reactions by Modulating the Kallikrein/Kinin System
Bacteria-controlled regulation of host responses to infection is an important virulence mechanism that has been demonstrated to contribute to disease progression. Here we report that the human pathogen Streptococcus pyogenes employs the procarboxypeptidase TAR (thrombin-activatablefibrinolysis inhibitor) to modulate the kallikrein/kinin system. To this end, bacteria initiate a chain of events star
Varför etiska kommittéer?
Popular Abstract in Swedish Från 1980-talet har etiken diskuterats flitigt i samhället. Det har i samband med detta utvecklats etiska kommittéer. Etiska kommittéer är en typ av organ inom företag, branscher, professioner och andra organisationer som handhar etiska frågor och problem. De etiska kommittéerna fungerar rådgivande i etiska frågor, de kan fastställa etiska regler för en organisation ochThis thesis analyses the development of ethics committees from a sociology of law perspective and a social steerage perspective ("social control"). The main question is: Why are ethics committees established? Institutionalised ethics committee is a rather new phenomenon, which has become widely spread in the last 20 years. The study points out the public ethical debate since the 1980s as a major e
