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Från dröm till verkliget: en kvalitativ studie av några socialsekreterares verkligheter och drömmar

The main purpose of this paper is to describe and analyse how social worker on a specific Social Service Agency describe their experiences. My focus has been to concentrate on social worker, whose task is related to young people. The paper is presented from three different themes; work assignments, professional roles and projects in life. The central questions are; Which are the socialworker´s mai

Universal Balance?

In the ActivAbles and STARR projects we are developing interactive training tools for stroke survivors. As our initial user studies pointed to balance being a key ability, one of the developed tools is an interactive balance mat. While balance equipment is common, interactive balancing equipment for persons with poor balance is less common. Equipment exists for persons with good balance (eg. Wii),

Characterization of presynaptic 5-HT receptors on adrenergic nerves supplying the bovine ovarian follicle

1. The effects of 5-hydroxytryptamine (5-HT) on contraction and release of [3H]-noradrenaline were investigated in vitro in bovine ovarian follicle strips. Using available selective agonists and antagonists, an effort was made to characterize the type of receptor mediating the inhibitory effect of 5-HT on neurogenic contraction and release of [3H]-noradrenaline by electrical field stimulation. 2.

PHF1 fusions cause distinct gene expression and chromatin accessibility profiles in ossifying fibromyxoid tumors and mesenchymal cells

Ossifying fibromyxoid tumor (OFMT) is a soft tissue tumor frequently displaying gene fusions, most of which affect the PHF1 gene. PHF1 encodes plant homeodomain finger protein 1, which is involved in various processes regulating gene transcription, including those orchestrated by the polycomb repressor complex 2. Here, a series of 37 OFMTs, including 18 typical, 9 atypical, and 10 malignant varian

Simulation of near-infrared light propagation through the thorax of a neonate : Addressing the optimisation of source and detector positions for measuring lung oxygen content in preterm infants

Gas in scattering media absorption spectroscopy shortly called GASMAS, is a tunable diode laser spectroscopic technique developed for the measurement of gas present in turbid media. The technique relies on the sharp and specific absorption lines of gases which enables sensitive measurements of gas concentrations in the presence of a scattering solid medium with much broader absorption features. Th

An integrated transcriptomic- and proteomic-based approach to evaluate the human skin sensitization potential of glyphosate and its commercial agrochemical formulations

We investigated the skin sensitization hazard of glyphosate, the surfactant polyethylated tallow amine (POEA) and two commercial glyphosate-containing formulations using different omics-technologies based on a human dendritic cell (DC)-like cell line. First, the GARD™skin assay, investigating changes in the expression of 200 transcripts upon cell exposure to xenobiotics, was used for skin sensitiz

The moderating effects of comorbidity on treatment outcomes: Results from a randomized controlled trial of two panic-focused psychotherapies

Introduction: Individuals with Panic Disorder with or without Agoraphobia (PD/A) suffer from high rates of comorbidity. The present study aimed to address a knowledge gap about whether psychiatric comorbidity at baseline differentially influences, or moderates, outcomes in PD/A focused treatments.Methods: Data were drawn from a doubly-randomized preference trial of Panic Control Therapy (PCT) and

Pathogenesis and novel treatment against tuberculosis

Tuberculosis (TB), caused by Mycobacterium tuberculosis, remains one of the deadliest infectious diseases worldwide. In 2023, it accounted for approximately 1.25 million deaths, including 161,000 among individuals living with HIV, making it the leading cause of death from a single infectious agent. The growing prevalence of multidrug-resistant TB (MDR-TB) further complicates treatment and contribu

Improving the indoor air quality by using a surface emissions trap for exposure reduction

A prototype of a surface emissions trap, a new device for reducing emissions of volatile organic compounds and particulate matter from surfaces while allowing evaporation of moisture, was used to improve the indoor air quality of a school building with elevated air concentrations of 2-ethyl-1-hexanol. A clear improvement of the perceived air quality was noticed a few days after the trap had been a

A study of the performance of risk and vulnerability assessments by Swedish Public Agencies

Risk and vulnerability assessments (RVA) are vital components of the work conducted by public agencies at different levels, as part of the processes for governing and managing risks in the society. In Sweden, public agencies at all levels are required by legislation to perform risk and vulnerability assessments within their respective area of responsibility. The present paper presents a study of h

Clinical and Serological Correlates of Serum C1Q and Anti-C1Q Antibodies in South Africans With Systemic Lupus Erythematosus

Objective: To investigate prevalence and clinical correlates of serum C1q and anti-C1q antibody titres in black South Africans with systemic lupus erythematosus (SLE). Methods: Cross-sectional study of 96 SLE patients, 49 with lupus nephritis (LN). Anti-C1q antibodies were tested by ELISA. Serum C1q was measured as a percentage of normal by immunoelectrophoresis. Disease activity was assessed usin

Uncovering Core Qualities of Digital Interventions for Health Promotion : Perspectives From People With Intellectual Disabilities, Relatives, and Professionals

Background: People with intellectual disabilities experience significant health inequities. Digital interventions for health promotion are rarely designed from their specific needs. This study aimed to uncover core qualities of digital interventions for health promotion by exploring factors influencing health behaviours amongst people with intellectual disabilities. Methods: This study was conduct

Generative Artificial Intelligence and Cybersecurity Risks : Implications for Healthcare Security Based on Real-life Incidents

Background: The potential of generative artificial intelligence (genAI) tools, such as ChatGPT, is being increasingly explored in healthcare settings. However, the same tools also introduce significant cybersecurity risks that could compromise patient safety, data integrity, and institutional trust. This study aimed to examine real-world security breaches involving genAI and extrapolate their pote

New Interoperable Solutions for Cultural Heritage Protection : The ANCHISE Toolset

The illicit trafficking of cultural heritage represents a significant global challenge, exacerbated by digital technologies that facilitate unauthorised trade while offering new protection opportunities. The ANCHISE project addresses these challenges through a suite of six innovative, complementary tools designed to enhance the detection, prevention, and investigation of cultural property traffick

Gene therapy for epilepsy : An emerging, promising approach for a serious neurological disorder

Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti-seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and long-lasting solutions. By addressing the underlying c

The role of civil society networks in catalyzing agroecological transitions in Uganda

Agroecology is increasingly recognized as a transformative pathway for building resilient and equitable food systems and addressing climate challenges. In Uganda, civil society organization (CSO) networks play a pivotal role in promoting agroecology through training, advocacy, and the facilitation of farmer-led innovations. This study examined the role of the Participatory Ecological Land Use Mana

Immune responses to malaria - Across early life, chronic exposure, and acute malaria

Malaria caused by Plasmodium falciparum (P. falciparum) remains a major cause of morbidity and mortality, particularly in sub-Saharan Africa. Immunity develops gradually after repeated exposure and is largely mediated by antibodies, yet the mechanisms regulating the development and function of humoral immunity, including the roles of B-cell subsets and inflammatory mediators, remain incompletely u

Late diagnosis of HIV persists in Sweden : Differing social determinants among migrant and non-migrant people with HIV

Objective: To examine temporal changes in late diagnosis of HIV (LD) among migrant and non-migrant people with HIV in Sweden 2003–2023 and to assess demographic and socioeconomic risk factors for LD in these two populations. Methods: People with HIV diagnosed with HIV-1 in Sweden 2003–2023 were included (n = 6278). LD was defined as a first CD4+ T-cell count <350 cells/μL or an AIDS-defining event

Low levels of IgG2 and pneumococcal antibodies as predictors of benefit from IgG replacement in IgG subclass deficiency

Immunoglobulin G subclass deficiencies (IgGSD) are associated with recurrent respiratory tract infections. Tools to identify patients with IgGSD who benefit from immunoglobulin G replacement therapy (IgGRT) are lacking. This crossover study evaluated the number of antibiotic-demanding infections on and after up to 18 mo off IgGRT in 28 patients with IgGSD. Pneumococcal antibodies against 21 seroty