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Challenges in drought monitoring hinder social development. In this study, a robust drought monitoring framework composed of ten indicators was established based on the standard precipitation actual evapotranspiration (SPAEI) index calculated using the maximum entropy production (MEP) model. Additionally, the relationship between meteorological drought and agricultural development was analyzed. Th
Diabetes is a highly heterogeneous condition; yet, it is diagnosed by measuring a single blood-borne metabolite, glucose, irrespective of aetiology. Although pragmatically helpful, disease classification can become complex and limit advances in research and medical care. Here, we describe diabetes heterogeneity, highlighting recent approaches that could facilitate management by integrating three d
Structural deterioration and increasing load demand are two main factors that compromise the serviceability and functioning of civil constructions. The vastity of the bridge portfolio and the few resources available require maintenance optimization to provide the required user safety. In this context, vibration-based monitoring may provide information about the structural performance and support d
Prediabetes is a metabolic condition associated with gut mi-crobiome composition, although mechanisms remain elu-sive. We searched for fecal metabolites, a readout of gut microbiome function, associated with impaired fasting glucose (IFG) in 142 individuals with IFG and 1,105 healthy individuals from the UK Adult Twin Registry (TwinsUK). We used the Cooperative Health Research in the Region of Aug
The northern hemisphere has experienced regional cooling, especially during the global warming hiatus (1998-2012) due to ocean energy redistribution. However, the lack of studies about the natural cooling effects hampers our understanding of vegetation responses to climate change. Using 15,125 ground phenological time series at 3,620 sites since the 1950s and 31-year satellite greenness observatio
Introduction: Elevated red cell distribution width (RDW) has been associated with a range of health outcomes. This study aims to examine prognostic and etiological roles of RDW levels, both phenotypic and genetic predisposition, in predicting cardiovascular outcomes, diabetes, chronic kidney disease (CKD) and mortality. Methods: We studied 27,141 middle-aged adults from the Malmö Diet and Cancer s
Worldwide, racial and ethnic minorities have been disproportionately impacted by COVID-19 with increased risk of infection, its related complications, and death. In the initial phase of population-based vaccination in the United States (U.S.) and United Kingdom (U.K.), vaccine hesitancy may result in differences in uptake. We performed a cohort study among U.S. and U.K. participants who volunteere
The present study assessed the temporal associations of ~ 300 lifestyle exposures with nine cardiometabolic traits to identify exposures/exposure groups that might inform lifestyle interventions for the reduction of cardiometabolic disease risk. The analyses were undertaken in a longitudinal sample comprising > 31,000 adults living in northern Sweden. Linear mixed models were used to assess the av
The complex genetic architecture of type-2-diabetes (T2D) includes gene-by-environment (G×E) and gene-by-gene (G×G) interactions. To identify G×E and G×G, we screened markers for patterns indicative of interactions (relationship loci [rQTL] and variance heterogeneity loci [vQTL]). rQTL exist when the correlation between multiple traits varies by genotype and vQTL occur when the variance of a trait
Warmer or cooler spring in northern high latitudes will, for the most part, directly impact gross primary productivity (GPP) of ecosystems, but also carry consequences for the upcoming seasonal GPP. Spatiotemporal patterns of these legacy effects are still largely unknown but important for improving our understanding of how plant phenology is associated with vegetation dynamics. In this study, imp
Assessing the causal effects of individual dietary macronutrients and cardiometabolic disease is challenging owing to the complexity to distinguish direct effects from those mediated or confounded by other factors. To estimate these effects, intake of protein, carbohydrate, sugar, fat, and its subtypes were obtained using food frequency data derived from a Swedish population-based cohort (n~60,000
Background: Hypertension remains a major risk factor for cardiovascular diseases, but the underlying mechanisms are not well understood. We hypothesize that appropriate mechanotransduction and contractile function in vascular smooth muscle cells are crucial to maintain vascular wall integrity. The Hippo pathway effectors YAP (yes-associated protein 1) and TAZ (WW domain containing transcription re
This study focuses on the trends and the causes of variation in actual evapotranspiration (AET) around the warming hiatus over China by a comprehensive analysis applying various temporal–spatial methods. It is observed that the annual AET showed a different trend around 2000 for China as a whole. By employing segmented regression analysis for detecting warming hiatus points, high temporal inconsis
Peatlands have acted as net CO2 sinks over millennia, exerting a global climate cooling effect. Rapid warming at northern latitudes, where peatlands are abundant, can disturb their CO2 sink function. Here we show that sensitivity of peatland net CO2 exchange to warming changes in sign and magnitude across seasons, resulting in complex net CO2 sink responses. We use multiannual net CO2 exchange obs
Purpose: The triglyceride-glucose index (TyG index) is a marker of insulin resistance and metabolic dysfunction and has the advantage of being universally available. Although recent evidence suggests the TyG index has relevance to respiratory health, there have been no prospective studies assessing its value as a biomarker for chronic lung diseases. We aim to assess the TyG index as a potential ri
Morpho-taxonomic studies of cetrarioid lichens from India recorded 46 species representing Cetraria, Melanelia, Nephromopsis, and Platismatia. Nephromopsis awasthii is described as new to science; and Cetraria endochrysea, C. sinensis, Melanelia agnata, Nephromopsis ciliaris, N. morrisonicola, N. pseudocomplicata, N. pseudoweberi, N. rugosa, N. weii, and N. yunnanensis are reported for the first tMorpho-taxonomic studies of cetrarioid lichens from India recorded 46 species representing Cetraria, Melanelia, Nephromopsis, and Platismatia. Nephromopsis awasthii is described as new to science; and Cetraria endochrysea, C. sinensis, Melanelia agnata, Nephromopsis ciliaris, N. morrisonicola, N. pseudocomplicata, N. pseudoweberi, N. rugosa, N. weii, and N. yunnanensis are reported for the first t
