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A rapid increase in incidence of non-Hodgkin lymphoma (NHL) has been reported from many countries. Exposure to certain pesticides and organochlorines has been shown to be risk factors. Epstein-Barr virus (EBV) is a human herpesvirus that has been associated with some subgroups of NHL, such as Burkitt lymphoma and lymphomas related to severe immunosuppression. In this study, we measured lipid adjus
The interest for studying server systems subject to cloned requests has recently increased. In this paper we present a model that allows us to equivalently represent a system of servers with cloned requests, as a single server. The model is very general, and we show that no assumptions on either inter-arrival or service time distributions are required, allowing for, e.g., both heterogeneity and d
Cognitive decline is one of the hallmarks of aging and can vary from mild cognitive impairment to dementia to Alzheimer's disease. In addition to some lifestyle interventions, there is room for the use of nutraceuticals/functional foods as pharma-nutritional tools to lessen the burden of cognitive decline before it worsens. We previously reported the promising molecular actions of milk fat globule
Cotton production is reaching a global limit, leading to a growing demand for bio-based textile fibers produced by other means. Textile fibers based on regenerated cellulose from wood holds great potential, but in order to produce fibers, the components need to be dissolved in suitable solvents. Furthermore, the dissolution process of cellulose is not yet fully understood. In this study, we invest
Hjärntumörer utgör omkring 2 procent av alla cancerdiagnoser och den vanligaste elakartade hjärntumörtypen är glioblastom (GBM). Patienter med GBM behandlas i dag med kirurgi, cellgifter och strålbehandling, men sjukdomen går sällan att bota och det krävs nya och mer effektiva behandlingsstrategier.I min doktorsavhandling har jag använt tre olika musmodeller, kallade GL261, KR158 och SB28, för attAdvances in surgery, chemo- and radiotherapy have only modestly improved survival rates of malignant brain tumor patients during the last decades. Emerging evidence suggests that an efficient treatment of malignant brain tumors will likely require the management of multiple aspects of tumor pathobiology in order to manipulate features as tumor heterogeneity and tumor immunosuppression. Immunothera
The sharing economy has become prominent in the policy, business and academic discourse as a way to achieve greater levels of resource efficiency in sustainability transitions. An example is carsharing, which is regarded as a potential lever for change in sustainable mobility transitions. In this article we, apply the "ecologies of business models" perspective to investigate how carsharing initiat
The presence of serotonin (5-hydroxytryptamine [5-HT]) in pancreatic endocrine cells is well established. Nevertheless, recent advances are only now unraveling the signaling network involving 5-HT that partly regulates the release of hormones emanating from the islets of Langerhans. It is widely accepted that failure of the pancreatic β-cell to release sufficient amounts of insulin is the main cul
Vascular bio-scaffolds produced from decellularized tissue offer a promising material for treatment of several types of cardiovascular diseases. These materials have the potential to maintain the functional properties of the extracellular matrix (ECM), and allow for growth and remodeling in vivo. The most commonly used methods for decellularization are based on chemicals and enzymes combinations,
The dynamical properties of large-scale, long-term phase synchronization behavior in the alpha range of electroencephalographic signals were investigated. We observed dynamical phase synchronization and presented evidence of an underlying spatiotemporal ordering. Fluctuations in the duration of episodes of intermittent synchrony are scale-invariant. Moreover, the exponent used to describe this beh
The direct reprogramming of adult skin fibroblasts to neurons is thought to be controlled by a small set of interacting gene regulators. Here, we investigate how the interaction dynamics between these regulating factors coordinate cellular decision making in direct neuronal reprogramming. We put forward a quantitative model of the governing gene regulatory system, supported by measurements of mRNA
Wind energy is an important source of bat mortality worldwide. Extensive mortality data were gathered by a provincial surveillance program carried out at wind farms in lowland Mediterranean areas of the province of Cadiz, Andalusia (South Spain) between 2005 and 2016. As many as 2,371 bat fatalities were found. We determined the patterns of fatality in this sample and tested the quality of the sur
Visst vore det fint om vi kunde producera nödvändiga kemikalier mer effektivt, förse alla människor med de läkemedel de behöver till en lägre kostnad än vad som är möjligt idag, och förhindra översvämningar i stadsmiljö? Men vad har dessa tre ting gemensamt, egentligen? Jo, att man kan optimera de olika processer som ligger bakom alla tre! Processer finns i princip överallt i världen, komplexa som eComplex processes can be seen as a series of actions, changes, and/or events that are related in different temporospatial manners, and thus are potentially difficult to understand. Optimizing such a process is therefore not necessarily a simple feat, and doing it experimentally may become both time-consuming and expensive. Computer-aided optimization therefore lends itself as a viable alternative,
This contribution aims to deal with innovation policy from the perspective of the systems of innovation approach. The intention is to address basic principles related to national, regional or local as well as sectoral systems of innovation and the policy implications emerging from these. Hence, there will be a very strong emphasis on policy in what follows. However, it is essential, of course, tha
The variance in phenotypic trait values is a product of environmental and genetic variation. The sensitivity of traits to environmental variation has a genetic component and is likely to be under selection. However, there are few studies investigating the evolution of this sensitivity, in part due to the challenges of estimating the environmental variance. The livestock literature provides a wealt
