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The climate change in northern Europe is not only leading to more extreme weather events but also causing long dry summers. This affects the moisture content of the ground and the vegetation. Causing an increased number of wildfires within Germany posing a risk to the environment, society, and firefighters. Surface fire spread in wildfires can be influenced by several environmental conditions and

Sensory traits shape animal lifestyles due to the central role they play in retrieving and processing environmental information. However, being some of the most energetically expensive tissues to build and maintain, ecological demands often modulate investment in these organs. Evidence that ecology shapes the evolution of sensory traits is plenty, but is heavily biased towards vertebrates and has

Non-invasive MRI is widely used to assess and monitor ischemic stroke, yet conventional approaches often lack sensitivity to subtle microstructural changes and struggle to evaluate tissue viability across lesion, penumbra, and distal regions. In this study, frequency dependent diffusion tensor distribution imaging (ωDTD) was combined with clustering of diffusion tensor distributions D(ω) and multi

The aim of this study was to investigate the frequency of p53 alterations in bilateral breast cancer and to evaluate a possible clonal relationship between the paired tumours regarding p53 alteration and other pathobiological variables. Tumours from 34 patients were investigated with immunohistochemistry, single strand conformation polymorphism analysis and DNA-sequence analysis applied to exons 5

In this study, we have investigated the dynamic behavior of colloidal rods within their isotropic phase, employing multispeckle ultrasmall-angle x-ray photon correlation spectroscopy (UA-XPCS) focusing on the understanding of the interplay between structure and dynamics at the nearest-neighbor length scale. While prior research has primarily focused on the structural aspects, our work addresses th

High-latitude ecosystems are undergoing rapid climate warming, yet long-term ecological response remain poorly understood due to the scarcity of sustained monitoring records. We analyse a unique 40-year dataset from a subarctic mountain birch ( Betula pubescens ssp. czerepanovii ) ecosystem in northern Fennoscandia, integrating climate, plant reproduction, insect herbivory, phenology, and large he

PURPOSE OF REVIEW: This review aims to give an overview of recent advances in the clinical management of children <18 years of age with end-stage pulmonary hypertension refractory to conventional medical therapy.RECENT FINDINGS/SUMMARY: The increased awareness and characterization of pediatric pulmonary vascular disease has amounted more data toward creating an accurate, and comprehensive, risk pr

The proline-rich domain (PRD) of the tumor suppressor p53 plays a central role in modulating conformational dynamics and molecular interactions, yet its intrinsic structural behavior remains incompletely understood. Here, we combine extensive all-atom molecular dynamics simulations with biophysical validation to characterize the conformational ensemble of the p53 PRD. The domain behaves as an intr

In recent years the treatment of cancer with radioactive drugs, here termed molecular radiotherapy (MRT), has emerged to take a place alongside other treatment modalities, particularly non-radioactive drugs (NRDs) and external beam radiotherapy (EBRT). A purpose-built tool was developed within the Python programming environment to review the evolution of clinical trials performed in the first quar

We report on the effect of magnetic impurities on the microscopic superconducting (SC) properties of the kagome-lattice superconductor La(Ru1-xFex)3Si2 using muon spin relaxation/rotation. A strong suppression of the superconducting critical temperature Tc, the SC volume fraction, and the superfluid density was observed. We further find a correlation between the superfluid density and Tc which is

Protecting qubits from perturbations is a central challenge in quantum computing. Topological superconductors with separated Majorana bound states (MBSs) provide a strong form of protection that only depends on the locality of perturbations. While the link between MBS separation, robust degeneracy, and protected braiding is well understood in noninteracting systems, recent experimental progress in

BACKGROUND: It remains unclear why cool temperatures cause more persistent adverse health effects compared to hot weather. Fluid homeostasis may constitute a causal link between past temperatures and adverse health effects. In this study we investigated the association between past outdoor temperatures and current fluid homeostasis.METHODS: We studied participants from five cohorts during three de

UNLABELLED: Children gain increased health and well-being by participating in physical activity. Children with cerebral palsy who are ambulatory (CP-A) are known to be less physically active than children without physical disabilities, making them an important group of children to support in becoming more physically active. Assistive technologies, such as eHealth, may support physical exercise in

PURPOSE: To elucidate the pathophysiology of the carotid sinus reflex in a large cohort of patients with suspected reflex syncope.METHOD: We reviewed an electronic database of patients with suspected reflex syncope who underwent carotid sinus massage. The diagnostic protocol included both right and left massage, in supine and upright positions, followed by tilt testing.RESULTS: The cohort included

Preventing obsessive–compulsive disorder (OCD) before it emerges has long been considered a central, yet elusive, goal for researchers. Achieving this will likely require identifying individuals at elevated risk and intervening during critical developmental periods before the onset of impairing symptoms. This trial evaluated the feasibility of a brief parent-guided online targeted prevention progr

Populärvetenskaplig sammanfattning: Allt fler rapporter har kommit under de senaste åren som visar på att våg- och stormklimatet har förvärrats sedan 1960-talet. Detta har oroat bland andra återförsäkringsbolag som har betalat ut allt mer pengar till stormrelaterade skador de senaste åren. Andra undersökningar har visat att det nuvarande storm- och vågklimatet inte är värre än det var i början av The effects of a global climatic change on the wind climate of northwestern Europe are investigated with the aid of a regional climate model. There have up to date been few studies of how the wind climate will react to a greenhouse gas warming. Those that have been done are mostly global scale studies and centered on changes in storm activity during the winter season. I’m using data from a regiona