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Axonal injury is an important contributor to the behavioral deficits observed following traumatic brain injury (TBI). Additionally, loss of myelin and/or oligodendrocytes can negatively influence signal transduction and axon integrity. Apoptotic oligodendrocytes, changes in the oligodendrocyte progenitor cell (OPC) population and loss of myelin were evaluated at 2, 7 and 21 days following TBI. We
Irreversible inhibition by molecular oxygen (O 2) complicates the use of [FeFe]-hydrogenases (HydA) for biotechnological hydrogen (H 2) production. Modification by O 2 of the active site six-iron complex denoted as the H-cluster ([4Fe4S]-2Fe H) of HydA1 from the green alga Chlamydomonas reinhardtii was characterized by x-ray absorption spectroscopy at the iron K-edge. In a time-resolved approach,
Ossifying fibromyxoid tumor (OFMT) is a soft tissue tumor frequently displaying gene fusions, most of which affect the PHF1 gene. PHF1 encodes plant homeodomain finger protein 1, which is involved in various processes regulating gene transcription, including those orchestrated by the polycomb repressor complex 2. Here, a series of 37 OFMTs, including 18 typical, 9 atypical, and 10 malignant varian
Resultaten i denna avhandling ökar vår kunskap om hur evolutionen av feromondetektering hos fjärilar gått till.Luktsinnet är viktigt för de flesta djur, inklusive människor, hundar, insekter och många andra. Hos insekter, särskilt nattfjärilar och flugor, används luktsinnet för att hitta parningspartners, föda, äggläggningsställen och att undkomma fiender.Feromoner är kemikalier som produceras ochIn moths, females produce sex pheromone compounds to attract males over a long distance for mating. The antennae of moths and many other insects have specialized odorant receptors (ORs), called pheromone receptors (PRs), to sense the pheromone compounds and they group in a monophyletic clade (PR clade).In this thesis, I investigated and compared various components of the olfactory system in differ
An improved Volume of Fluid (VOF) method is presented which is applicable to high density ratio 3D flows for a large range of bubble Reynolds number (Re). The method is based on the Navier-Stokes equations for incompressible multi-phase flows which are discretized on a Cartesian staggered grid. The multi-grid technique together with the pressure-velocity coupling scheme for multi-phase flows have
Transplantation of embryonic ventral mesencephalon is a potential therapy for patients with Parkinson's disease. As only around 5-10% of embryonic dopaminergic neurons survive grafting into the adult striatum, it is considered necessary to use multiple donor embryos. To increase the survival of the grafted dopaminergic neurons, the clinical transplantation program in Lund currently employs the lip
Att polisen använder sig av provokativa åtgärder i brottsbekämpningen är i viss mån accepterat i Sverige. Brottsprovokation och bevisprovokation anses vara nödvändiga metoder för att bekämpa allvarlig och organiserad brottslighet och har blivit ett allt vanligare inslag i polisens arbete sedan början av 1980-talet. Sedan dess har även en förändring skett vad gäller inställningen till den provoceraThe use of provocative investigative measures is in Sweden an accepted method in the control of crime. These measures are considered to be essential parts in the fight against serious and organized criminality and have become a more commonly used instrument for the police since the early 1980’s. Since then, there has been a change concerning how a criminal is treated legally after being subject to
Authors: Andersson, Carl-Johan and Löfstrand, Pontus Supervisors: Nilsson, Lars J. Department of Technology and Society, Environmental and Energy Systems Studies, Lund University. Yard, Stefan, Department of Business Administration, Lund University. Kling, Åsa, Vattenfall Utveckling AB. Issues: One reasonable effect of emissions trading is arising incentives for cutting fossil fuel usage. One effe
Queuing during evacuation is a phenomenon that has to be regarded when designing large buildings with high occupant loads. In theory it would be possible to eliminate or at least reduce the queuing time when evacuating a building if the building is designed with a large number of exits. The problem is that exits equal money and for that reason it has to be assumed that the building constructors’ a
Uppsatsen beskriver gällande rätt vid umgängestvister rörande barn och dess föräldrar i FN:s Barnkonvention, i den europeiska konventionen angående skydd för de mänskliga rättigheterna och de grundläggande friheterna och i svensk rätt. Uppsatsens syfte är att med hjälp av gällande rätt undersöka huruvida umgängesreglerna innebär en rättighet eller en skyldighet för barn att umgås med föräldrarna. This paper describes the current law concerning the right of access between children and parents in the United Nations Convention on the Rights of the Child (CRC), in the European Convention for the Protection of Human Rights and Fundamental Freedoms and in Swedish law. The intent of this paper is to discuss whether the current law regarding access makes it a right or an obligation for a child to
Background The trend of postponed reproduction to late in life has increased demand for fertility treatment. The current program of subsidized ART-treatment in Sweden is thoroughly debated and critiqued. The Swedish National Council on Medical Ethics has highlighted the ethical shortcomings of the current system and called for a program change. This thesis expands on the proposal and introduces a
Emerging technologies have the potential to bring numerous new opportunities and solutions to the existing challenges, including addressing sustainable development goals (SDGs). Particular hopes are given to areas of the life that require our urgent action, these include but are not limited to medicine and food security. Scientists investigate how these technological advances can be applied for th
Syftet med uppsatsen är att diskutera om Sverige borde införa ett så kallat internationellt fartygsregister likt dem som funnits i Norge och Danmark sedan slutet av 1980-talet. Skillnaden mellan internationella fartygsregister och ordinära fartygsregister är att internationella register tillåter anställning av besättning från låglöneländer på lokala villkor. I uppsatsen redogör jag för de historThe aim of this thesis is to discuss whether Sweden should launch a so-called international ship register, similar to those launched by Norway and Denmark in the late 1980’s. The difference between international and ordinary ship registers is that international registers allow the employment of crews from low wage countries on local conditions. My thesis examines the historical circumstances whic
Huntington’s disease is a hereditary neurodegenerative disease caused by an expansion of CAG repeats in the huntingtin (HTT) gene. HD is fully penetrant around 40 CAG repeats and is characterized by motor impairments, psychiatric disturbances and cognitive deterioration. Unintended weight loss is also a clinical feature of HD, leading to reduced morality and a decline in quality of life in HD pati
Context. The Gaia satellite will observe about one billion stars and other point-like sources. The astrometric core solution will determine the astrometric parameters (position, parallax, and proper motion) for a subset of these sources, using a global solution approach which must also include a large number of parameters for the satellite attitude and optical instrument. The accurate and efficien
In today’s connected world, businesses are increasingly going online. Additionally, the online industry is transforming into an international business arena, flourishing with opportunities to grow and expand. However, the internationalisation has raised a number of challenging issues. One of these challenges is foreign exchange. Foreign exchange is needed to sell and buy on markets with different
Introduction: Gas chromatography-mass spectrometry (GC-MS) is a powerful tool when used in metabolomics, the study of small molecules in the body, and investigating new modes of using it might lead to even better tools for diagnostics and research. Background: Chemical ionization (CI) for GC-tandem MS (GC-MS/MS) is relatively rarely used compared to the more commonplace electron ionization (EI).
Från att den svenska synen på avtalsförhållanden tidigare betonat parternas avtalsfrihet och starkt präglats av en restriktivitet mot att fylla ut avtal med förpliktelser som inte uttryckligen följer av dessa, har utvecklingen på avtalsrättens område gått emot en syn som snarare ser avtalsförhållandet som ett samarbetsförhållande än ett motpartsförhållande. Svenska avtalsparter har i takt med den The Swedish view of contractual relations has previously emphasized the parties’ contractual freedom and has been characterized by a restrictiveness towards imposing obligations on the parties beyond what expressly follows from the agreement. Development in the area of contract law has led to the contractual relationship being seen rather as a cooperative relationship than a counter-party relation
The actual concept of food security focuses on four food security dimensions: food availability, food access, food utilization and food stability of which eight indicators were identified for this study. The study aims to evaluate vulnerability to chronic food and nutrition insecurity, one of the food stability types, in Ethiopia; and examines the relationship between four food security dimensions
Syfte: Syftet med studien är att titta på hur ett företag med sina risker spridda över olika branscher arbetar med att förstärka sin verksamhet i förhållande till framfarten av en global kris, i detta fall Covid-19. För denna studiens genomförande har vi valt att förhålla oss till företagets upplevda styrkor i förhållande till krishantering och hur denna krishantering kan hjälpa till att bibehållaPurpose: The purpose of the study is to look at how a company with its risks spread across different industries is working to strengthen its operations in relation to the progress of a global crisis, in this case Covid-19. As the purpose of this study, we have chosen to relate to the company's perceived strengths in relation to crisis management and how this crisis management can help maintain
