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Popular Abstract in Swedish Cancer i levern kan vara av två typer - antingen kan den ha sitt ursprung från levern och kallas primär levercancer eller också är den en spridning av tumör till levern från en annan plats i kroppen, s k dottersvulst eller metastas. Idag är kirurgi av tumörer i levern förstahandsbehandling, men tyvärr är det bara 1/10 patienter som har tumör i levern som kan bli aktuell
Popular Abstract in Swedish Effektiv sökning och sortering är byggstenar som används vid nästan all algoritmdesign. Sökrutiner och sorteringrutiner implementeras ofta slentrianmässigt med hjälp av algoritmer som bygger på parvisa jämförelser mellan element. I denna avhandling argumenterar vi för att algoritmer som också utnyttjar elementens interna struktur är överlägsna i många avseenden, både prEfficient sorting and searching are corner-stones in algorithm design. In computer science it has become a deep-rooted habit to use comparison-based methods to solve these problems. In this thesis we argue that radix sorting and searching algorithms are superior in many respects, both practical and theoretical. They are often remarkably simple and many, if not most, sorting and searching problems
We introduce a common framework for the definition and operations on the different multiple view tensors. The novelty of the proposed formulation is to not fix any parameters of the camera matrices, but instead let a group act on them and look at the different orbits. In this setting the multiple view geometry can be viewed as a four-dimensional linear manifold in ℛ3m, where m denotes the
The interior stress problem is solved numerically for a single-edge notched specimen under uniaxial load. The algorithm is based on a modification of a Fredholm second-kind integral equation with compact operators due to Muskhelishvili. Several singular basis functions for each of the seven corners in the geometry enable high uniform resolution of the stress field with a modest number of discretiz
Gaia is ESA’s space astrometry mission with a foreseen launch date in early 2012. Its main objective is to perform a stellar census of the 1000 Million brightest objects in our galaxy (completeness to V=20 mag) from which an astrometric catalog of micro-arcsec level accuracy will be constructed. A key element in this endeavor is the Astrometric Global Iterative Solution (AGIS). A core part of AGIS
In this paper, we propose a gridless method for estimating an unknown number of fundamental frequencies. Starting with a conventional dictionary matrix, containing sets of candidate fundamental frequencies and their corresponding harmonics, a non-convex log-sum cost function is formed such that it imposes the harmonic structure and treats every fundamental frequency in the dictionary as a paramete
Myoglobin is a primary iron, and oxygen-binding protein of muscle tissues and levels can be an important diagnostic biomarker for acute myocardial infarction, myocardial necrosis, or other cardiac diseases. The establishment of myoglobin recognition systems is important because of its protein's structural and functional values in physiology, biochemistry, and diagnostic value in some damaged muscl
Evaniid wasps develop as solitary egg predators within the oothecae of cockroaches. Fossil evaniids are relatively common compared with most other parasitoid Hymenoptera, undoubtedly due to their searching for host cockroaches on tree trunks and thus an increased chance of being trapped in tree resin. The genus Parevania Kieffer, 1907 is widely distributed through the Old World and is also known f
In many ways can Thomas More’s vision in his classic Utopia from 1516 lend itself to describe Sweden as no longer a great power in war, as had been the case in the 17th and early 18th century, but an egalitarian nation and also in other aspects a peaceful, humanitarian example to follow. The ideal that More envisioned is to be understood as an unattainable and therefore unrealistic dream; his idea
The ATLAS experiment has observed 1995 Z boson candidates in data corresponding to 0.15 nb(-1) of integrated luminosity obtained in the 2011 LHC Pb + Pb run at root s(NN) = 2.76 TeV. The Z bosons are reconstructed via dielectron and dimuon decay channels, with a background contamination of less than 3%. Results from the two channels are consistent and are combined. Within the statistical and syste
We apply first- and second-order splitting schemes to the differential Riccati equation. Such equations are very important in e.g. linear quadratic regulator (LQR) problems, where they provide a link between the state of the system and the optimal input. The methods can also be extended to generalized Riccati equations, e.g. arising from LQR problems given in implicit form. In contrast to previous
In a number of autoimmune diseases, for example, rheumatoid arthritis and systemic lupus erythematosus, it is known that autoantibodies are present before the clinical onset. Recently we have shown that autoantibodies can be found many years before symptom onset in primary Sjögren's syndrome. This implies that screening for autoantibodies may be used to identify individuals at risk of developing s
The circadian clock measures time across a 24h period, increasing fitness by phasing biological processes to the most appropriate time of day. The interlocking feedback loop mechanism of the clock is conserved across species; however, the number of loops varies. Mathematical and computational analyses have suggested that loop complexity affects the overall flexibility of the oscillator, including
The local governments of EU member countries are attracted to the possibility of receiving EU funding. However, as the governance structures of EU funds are complex and dynamic, municipalities are increasingly drawing on the knowledge and resources of ‘EU experts’ who mediate and provide project support. This article contributes to our understanding of how EU cohesion policy is translated through
Urological problems can be caused by diseases that affect the bladder wall and its innervation. Contraction and relaxation of smooth muscle cells (SMCs) is essential for maintaining detrusor function and for emptying the bladder. It is well established that a family of regulatory proteins called Myocardin Related Transcription Factors (MRTFs) controls the property of SMCs. SMCs have a number
Aims: It has in recent years been established that epigenetic changes contribute to β-cell dysfunction and type 2 diabetes (T2D). For example, we have showed that the expression of histone deacetylase 7 (HDAC7) is increased in pancreatic islets of individuals with T2D and that increased levels of Hdac7 in β-cells impairs insulin secretion. The HDAC inhibitor MC1568 rescued this secretory impairmen
