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AIMS: Experiencing an acute myocardial infarction (AMI) is a life-threatening event and use of statins can reduce the probability of recurrence and improve long term survival. However, the effectiveness of statins in the real-world setting may be lower than the reported efficacy in randomized clinical trials. Therefore, we aimed to investigate whether low statin treatment adherence during the year
Background: For a significant proportion of the older population, increasing age is associated with health problems and worsening health. Older family caregivers are largely responsible for care of next-of-kin living at home, which impacts their own physical and mental health both positively and negatively. However, evidence is insufficient regarding the health situation of older caregivers. The a
Den svenska demografin förändras och antalet invånare äldre än 64 år väntas öka de kommande åren. Dessutom har urbaniseringen förändrats något, inte minst efter pandemin, då utflyttningen från storstäder till mindre orter ökat. Ökad flexibilitet i många yrken och delvis ändrade levnadsmönster har således resulterat i ett delvis minskat lägesberoende. Sammantaget står fastighetsmarknaden inför föräThe purpose of this study is to investigate what urban life really is and if (and in that case also how) urban life may be created and affected, primarily during the asset management phase. The study is conducted from the landowner’s perspective. Furthermore, the study aims at exploring what consequences and impact urban life has on the attractiveness and value of a place. The study is based on a
Sexualbrott är en brottstyp som präglas av betydande bevissvårigheter. I många fall saknas teknisk bevisning eller vittnesiakttagelser, vilket innebär att domstolens bedömning i hög grad vilar på parternas muntliga utsagor. Dessutom präglas sexualbrott av ett lågt lagföringsutfall och ett stort mörkertal, vilket gör rättsområdet särskilt angeläget att undersöka. Frågan är vad detta beror på, och hSexual offences are characterised by significant evidentiary challenges. In many cases, there is a lack of technical evidence or eyewitnesses, meaning that the court’s assessment largely relies on the parties’ oral statements. Combined with a low prosecution rate and a large number of unreported cases, this makes the legal area particularly important to examine. It raises questions about how credi
This degree project combines computational fluid dynamics (CFD) simulations with experimental validation using a Büchi B-290 spray dryer to study particle deposition patterns during spray drying of a glycerol-based solution. The CFD simulations were performed using ANSYS Fluent with a monophasic air model, where the liquid phase was represented as discrete inert particles injected via the Disc
This thesis presents a complete digital back-end implementation of a PN-dither least-mean-squares (LMS) background calibration scheme for a 12-bit, 500 MS/s pipeline analog-to-digital converter (ADC). The target converter, designed by a parallel analog project, comprises four 3-bit stages and a 4-bit final flash stage; its actual inter-stage gains depart substantially from their nominal values, re
Patients with Wilms tumor (WT) in general have excellent survival, but the prognosis of patients belonging to the subgroup of WT with diffuse anaplasia (DA) is poor due to frequent resistance to chemotherapy. We hypothesized that DA WT cells might undergo changes, such as acquiring a persistent tolerance to DNA damage and copy number aberrations (CNAs), which could eventually lead to their resista
Groundwater contamination is a threat to drinking water resources and ecosystems. Remediation by injection of chemical reagents into the aquifer may be preferred to excavation to reduce cost and environmental footprint. Yet, successful remediation requires complete contact between contamination and reagents. Subsurface heterogeneities are often responsible for diffusion into low-permeable zones, w
Ribbed channel flows are encountered in numerous engineering applications to promote turbulence and enhance heat transfer in various cooling passages, e.g., in turbine blades and at combustor walls. Numerical simulations have become an increasingly useful tool for providing insights into complex turbulence and flow separation, which are critical to the design and optimization of such channels. In
Popular Abstract in Swedish Vid framtagning av nya produkter måste man utgå ifrån de behov som den blivande kunden ställer i form av krav och önskemål på produkten för att den ska vara intressant att inhandla och använda. För att säkerställa att den blivande produkten har de egenskaper som efterfrågas, används idag omfattande simuleringar av den blivande produktens egenskaper. Simuleringar består The current trend in industry to encourage engineering designers to take an active part in the analysis of their own design solutions is apparent in many companies today, domestically as well as abroad. From a research project with the objective to develop a computer-based design system for the design of lightweight grippers, one of the major difficulties was to overcome the system users’ lack of
The purpose of this lecture is to shed light on a potential, and invite those who are interested to join in and make use of this potential. Here is the background: Starting with the Isaac Project in 1993, Certec has developed a technological/educational concept based on pictures as language for people with limited spoken language or none at all. There are a number of case studies (our own and ot
This dissertation investigates properties of rotating atomic nuclei. Studies are performed using the cranking model and in the particles + rotor model. Properties studied are energy spectra and electromagnetic transition probabilities. The thesis also investigates the use of different liquid drop models at high spin values and studies the use of the particle + rotor approximation for the descripti
This thesis, which is based on four original papers, covers different aspects of the evolvement and development of proteomic platforms and the construction of human synthetic antibody libraries for the isolation of antibody reagents has been very central. There is an accelerating need for technologies capable of providing proteomic analysis of high sensitivity with good accuracy and an overall bro
The social dimensions of the great transformation from an agrarian to an industrial society are still poorly understood. Today there are challenging opportunities to study such processes in Asia, and to do this against a comparative background of similar transformations elsewhere, for example in Europe, and in the light of theories of social mobility, industrialisation and agrarian change. This st
Bedömningen av om det föreligger orsakssamband mellan gärningsmannens handlande och en följd är en fråga som mestadels har diskuterats i juridisk doktrin. Den 16 januari 2024 avkunnade HD dom i mål B 3014-23 och namngav den ”Dödsorsaken”. I domen diskuteras vilka krav som ställs på orsaksrekvisitet för att kunna avgöra om en person har orsakat ett döds-fall. HD konstaterar att det vid konkurrerandThe assessment on whether there is a causal link between the perpetrators actions and an effect is a question that mostly discussed in judicial litera-ture. Recently, The Supreme Court delivered a judgment with the case number B 3014-23 on January 16, 2024, regarding this matter. It was named “The Cause of Death”. In the judgement, the Supreme Court clari-fies how to handle competing and cooperati
Scania has always been susceptible to damages caused by storms along its coasts which also holds true for the east coast in Scania where there is a great need of coastal protection for households and infrastructure alike. One example is the Kivik waste water treatment plant (WWTP) which is a newly built establishment with glass windows situated 30 meters from the east coast and provides its servic
An open-label, crossover randomized study was performed to compare the pharmacokinetics (PK) of damoctocog alfa pegol and rurioctocog alfa pegol, two recombinant factor VIII (FVIII) products indicated in patients with hemophilia A, both conjugated to polyethylene glycol to reduce clearance and extend time in circulation. Adult patients (N = 18) with severe hemophilia A (FVIII < 1 IU/dL), previousl
Many cell functions rely on the ability of microtubules to self-organize as complex networks. In plants, cortical microtubules are essential to determine cell shape as they guide the deposition of cellulose microfibrils, and thus control mechanical anisotropy in the cell wall. Here we analyze how, in turn, cell shape may influence microtubule behavior. Using a computational model of microtubules e
Introduction People with anterior cruciate ligament (ACL) reconstruction (ACLR) are at high risk of sustaining a graft rupture and/or contra-lateral ACL injury. The main factors that may predispose individuals for subsequent ACL injuries are, however, not established. To reduce the risk of reinjuries, it is of particular interest to identify modifiable risk-factors, for instance, those related to
Periodic structures are known to produce passbands and stopbands for propagation of vibration energy within the frequency domain. Sources vibrating harmonically at a frequency within a passband can lead to propagation of energy through propagating modes over long distances. However, sources vibrating at a frequency within a stopband excite only nearfields in the form of attenuating and evanescent
