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Changed Supply Chain Disruption Risks through Installation of a Pasteurizer – the case of Brämhults Juice AB

Brämhults Juice AB is a Swedish company producing fresh juice for the Scandinavian market. Fresh juice is rich in taste but has limited durability and must be treated with special care throughout the whole supply chain. Not only will the quality of the product be affected if mistreated, but there are also contamination risks meaning that people actually could get sick, although the risk is very sm

Perilipin expression in the islets of Langerhans and Surface expression in the baculovirus/insect cell system

Surface display in insect cells: Systems available for surface display that utilize bacterial phages are insufficient for displaying a number of eukaryotic proteins. By instead presenting proteins on the surface of eukaryotic cells or virus, some of these problems might be overcome. The baculovirus/insect cell system, which has a high expression rate and post-translational mashinery closely resemb

Design and Analysis of Nonmagnetic Specular Radar Absorbing Materials

The design and analysis of specular radar absorbing materials are investigated throughout the dissertation. Although the topic has been investigated for more than 60 years by many researchers and numerous designs have been proposed, still many technical challenges are remained unanswered. The basic questions are, e.g., the optimal thickness of a design, the possibility of utilization of unconventi

From the pancreatic beta cell to the endothelium:Pathophysiological aspects of Type 2 Diabetes

The incidence of Diabetes Mellitus increases globally in epidemic proportions. Type 2 Diabetes is the most prevalent form of Diabetes, comprising 90% of the patients. In Type 2 Diabetes, two processes contribute to the development of the disease: insufficient insulin secretion from the pancreatic ?-cell and insulin resistance of the target organs. This leads to loss of control of blood glucose lev

Palaeogeographic, climatic and tectonic change in southeastern Australia: the Late Neogene evolution of the Murray Basin

The Murray Basin is a low-lying but extensive intracratonic depocentre in southeastern Australia, preserving an extraordinary record of Late Neogene sedimentation. New stratigraphic and sedimento-logic data allow the long-term evolution of the basin to be re-evaluated and suggest a significant role for: (1) tectonism in controlling basin evolution, and (2) progressive and step-wise climatic change

Ring Flips Revisited: C-13 Relaxation Dispersion Measurements of Aromatic Side Chain Dynamics and Activation Barriers in Basic Pancreatic Trypsin Inhibitor

Intramolecular motions of proteins are critical for biological function. Transient structural fluctuations underlie a wide range of processes, including enzyme catalysis, ligand binding to buried sites, and generic protein motions, such as 180 degrees rotation of aromatic side chains in the protein interior, but remain poorly understood. Understanding the dynamics and molecular nature of concerted

Airborne cognitive systems in search of an appropriate context: Studies of the introduction of new technology in aviation using a cognitive systems engineering approach

Popular Abstract in Swedish Sammanfattning Teknik är alltid skapad för en förväntad brukare i ett antaget sammanhang. Inom kommersiell luftfart är dessa antaganden när det gäller design tydliga. Såväl besättning som utrustning är certifierad för en viss typ av operationer i enlighet med flygplanets drifthandbok. Trots denna genomtänkta definition av användare i sitt sammanhang händer det ändå attAbstract Technology is always designed for an assumed user in an assumed context. In commercial aviation, these design assumptions are clearly spelt out in that both crew and equipment are certificated for a specific operation as stated in the aircraft flight manual. Despite this well defined user context, the designed-for and the real contexts often differ enough so that adaptations of working p

Inhibition of Nitrification in Municipal Wastewater - Sources, Effects, Evaluation and Remedies

Today, as a rule, the most cost-effective way to remove nitrogen from municipal wastewater is the biological method based on nitrification and subsequent denitrification. All biological systems may be affected by toxicants, and biological nitrogen removal is no exception. An investigation of influent wastewaters from 109 Swedish municipal wastewater treatment plants was accomplished. Inhibitory s

New aspects of voltage-gated calcium channel regulation in pancreatic beta-cells - Relevance for insulin release and type 2 diabetes

Popular Abstract in German Spannungsgesteuerte Kalziumkanäle haben eine große Bedeutung in vielen elektrisch erregbaren Zellen, wie z.B. in Nervenzellen und pankreatischen beta-Zellen. Hier werden sie folgendermaßen aktiviert: In der Nahrung enthaltener Traubenzucker (Glukose) wird nach einer Mahlzeit über den Blutstrom im Körper verteilt und in die beta-Zellen über Glukosetransporter aufgenommen.Voltage-gated Ca2+ channels are essential transducers of cellular signals in many electrically excitable cells. In the pancreatic beta-cell they mediate controlled Ca2+ influx, which is the final trigger for Ca2+ dependent release (exocytosis) of the blood glucose lowering hormone insulin. Several subtypes of voltage-gated Ca2+ channels are known and the L-type has been found to be the main contri

Moisture transport and fixation in porous materials at high moisture levels

The work presented in this thesis focuses on developing methods of measuring moisture properties at high moisture levels. Paper I deal with a new method of measuring moisture diffusivity at high moisture levels. Papers II to IV present methods of measuring moisture storage capacity as well as results from such measurements. Paper V evaluates the use of thermal imaging to measure transient moisture

Bacteriophages and cryogels: A new efficient tool in bioseparation

Abstract Due to developments in the last decades in the field of protein production, new technologies for bio-separation have evolved. Especially in the field of affinity chromatography, the search for new ligands is of great interest. Besides the antibodies used as affinity ligands, synthetic ligands were introduced. Textile dyes were a first group to be introduced but despite their selectivity a

Knowledge Bases and the Geography of Innovation

Despite the ongoing globalisation of economic activities, innovation does not take place randomly distributed over space, but concentrates in certain locations. A central argument to explain the spatial concentration of innovation activities lies in the ability of geographical proximity to facilitate interactive learning and knowledge exchange, which in turn is seen as an important driver for regi

Global Proteome Survey -Transforming antibody-based affinity proteomics into a global discovery platform

Popular Abstract in Swedish En av de stora vetenskapliga bedrifterna hittills under 2000-talet är onekligen att man efter många års arbete för första gången lyckades kartlägga (sekvensera) samtliga mänskliga gener. Det mänskliga DNA:t är lokaliserat till cellkärnan och i princip så kan man likna en cellkärna med ett kontrollrum fyllt av manualer (DNA) som talar om cellens sammansättning och hur deProteomics is expected to generate new insights into biological processes as well as identify novel biomarkers and therapeutic targets since most biological functions are transmitted through proteins. However, due to the complexity displayed by a proteome and inherent limitations associated with current methodologies, proteomic analyses often result in incomplete coverage and inconsistent measurem

Our Selves in the Future : New Angles on Possible Selves

Popular Abstract in Swedish Avhandlingen handlar om den aspekt av människans självbild, eller självet, som på engelska kallas possible selves, och som på svenska skulle kunna kallas "möjliga själv" (en etablerad svensk översättning saknas). Detta är framtidsföreställningar eller framtidsbilder där vi ser oss själva i framtida situationer eller tillstånd, och teorin om möjliga själv presenterades fPossible selves are conceptions or images of ourselves in future states or situations. The theory about possible selves used in the present thesis was developed in a social cognitive tradition of research on the self, where the self is seen as a knowledge structure (Markus & Nurius, 1986). Possible selves are parts of this knowledge structure and possible selves are of importance for motivatio

Hygroscopic Properties of Aerosols from Open-Air Burning and Controlled Combustion of Biomass

The major uncertainty in predicting the influence of human activities on global climate change is the effect of aerosols. Two physical properties of aerosols largely controlling their influence on climate are the particle number size distribution and the interaction of the particles with the surrounding water vapor. The work presented in this thesis provides new information on the interaction bet

Konkurrenters rättsskydd vid olagligt statsstöd - ett svenskt dilemma

Sammanfattning Den 1 juli 2013 trädde den nya statsstödslagen i kraft. Den statliga utredning som dessförinnan tillsattes fick bland annat i uppdrag att analysera om det behövdes särskilda bestämmelser för att tredje part inför svensk domstol ska kunna yrka återkrav eller skadestånd under åberopande av genomförandeförbudet i artikel 108.3 FEUF och att lämna förslag på den författningsreglering soSummary On 1 July 2013 the new state aid act entered into force. The preceding Inquiry had been instructed to consider whether special provisions were needed to enable third parties to bring actions before the Swedish courts with reference to the standstill obligation in Article 108.3 TFEU, and to leave suggestions for any legislation that might be needed in that respect. The Inquiry deemed such

Konkurrens om högkvalificerad arbetskraft - en skatterättslig studie av expertskattens ändamålsenlighet i jämförelse med den danska forskerordningen

I dagens globala ekonomi råder det konkurrens om den högkvalificerade arbetskraften. Det är ett särskilt stort problem att attrahera denna lättrörliga personkategori till högskatteländer som Sverige och Danmark. Båda länderna har därför infört särskilda skattelättnader riktade mot denna personkrets. Den svenska expertskatten är reglerad i 11 kap 22-23 a §§ inkomstskattelagen och den danska forskerHigh-skilled workers are greatly valued on the global labor market. As a result, a number of countries have introduced targeted tax concessions for high-skilled labor in order to attract this particular part of the workforce. This is especially true for high-tax countries, concerned that the high tax rates dis¬courage high-skilled workers from locating in a particular country. Sweden and Denmark a

The role of SRC-like adaptor protein 2 (SLAP2) in receptor tyrosine kinase KIT signaling

SLAP2: A potential new strategy in fighting cancer Among more than 20,000 genes in humans, about 2% of genes encode a class of proteins referred to as kinases. A kinase is a protein, which transfers phosphate groups to proteins called substrate proteins. This process is named phosphorylation and almost all cellular behaviors are controlled by protein phosphorylation. Kinases mainly phosphorylate

Rotationsviskosimeter, RVB

To most people bitumen is an unknown material although it is the most important ingredient in asphalt pavements, something that everyone knows and uses every day. By merely distilling crude oil a substance is produced with unique properties and durability, which could not have been produced by synthetic means, at least not in those quantities used. The production is not that simple and the raw mat

Isolation of polystyrene-protein corona complex from bovine serum using size exclusion chromatography and expression of Daphnia magna’s proteins using EDDIE fusion technology

The comprehensive use of plastic globally has raised many questions about how it will affect living organisms once it is disposed of and reaches the ecosystem. Disposing of plastic in high amounts without recycling could lead to several toxic effects for aquatic organisms and eventually humans. Accumulation of plastic for a long time leads to its aggregation and/or degradation into small sizes in