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Purpose: In patients with hemophilia B, treatment with extended half-life (EHL) recombi-nant factor IX allows for longer dosing intervals while providing equal or superior bleeding protection compared with standard half-life products. This enables flexible, individualized treatment schedules, which reduce the burden of prophylaxis and improve patient outcomes. This analysis compared the efficacy o
Postdoc Contact details Email: sara [dot] arapiles [at] jur [dot] lu [dot] se Phone: +46 46 222 10 70Organisation Department of Law Room number: 322 Service point: 56 WebpageSara Arapiles profile in Lund University research portalOther affiliations Researcher Human Rights Law Profile area member LU Profile Area: Human rights Researcher Public International Law Publications Displaying of publicatio
https://www.law.lu.se/sara-arapiles - 2026-07-02
Streptococcus pyogenes (group A streptococcus) causes a variety of diseases, including acute pharyngitis, impetigo, rheumatic fever and the streptococcal toxic shock syndrome. Moreover, S. pyogenes was responsible for the classical example of a nosocomial infection, the epidemics of puerperal fever (childbed fever) that caused the death of numerous women in earlier centuries. The most extensively
The nervous system is constantly infiltrated by blood-derived sentinels known as perivascular macrophages. Their immediate precursors have not yet been identified in situ and the mechanism that governs their recruitment is mostly unknown. Here, we provide evidence that CD68 (+)GR(-) monocytes can give rise to perivascular macrophages in mice suffering from endotoxemia. After adhesion to the endoth
Disturbed haemostasis is a central finding in severe Streptococcus pyogenes infection. In particular, microthrombi are found both at the local site of infection and at distant sites. Platelets are responsible for maintaining vascular function and haemostasis. We report here that M1 protein of S. pyogenes triggers immune-mediated platelet activation and thrombus formation. M1 protein is released fr
A dry release method for fabrication of suspended nanostructures is presented. The technique has been combined with an anti-stiction treatment for fabrication of nanocantilever based nanoelectromechanical systems (NEMS). The process combines a dry release method, using a supporting layer of photoresist which is removed using oxygen ashing in a reactive ion etcher (RIE), with CHF3 plasma induced de
Recently, to reach zero emission levels, some new energy systems based on fuel cells have been developed. This paper presents a review of investigations of these systems by thermodynamics performance, mainly, energy and exergy analysis. With energy analysis, the performance of an energy conversion system cannot be effectively and accurately evaluated. But exergy analysis complements and reinforces
Despite the recent clinical success of T cell checkpoint inhibition targeting the CTLA-4 and PD-1 pathways, many patients either fail to achieve objective responses or they develop resistance to therapy. In some cases, poor responses to checkpoint blockade have been linked to suboptimal CD28 costimulation and the inability to generate and maintain a productive adaptive anti-tumor immune response.
Microsoft Word - NanoLund policy research visits_2.docx February 2017 Riktlinjer för stöd från NanoLund till internationella forskningsvistelser NanoLund önskar att stödja internationellt utbyte och inspirationsbesök i ledande internationella forskningsmiljöer. Pengar kan sökas närsomhelst under året från den exekutiva gruppen (ca 1 A4‐sida). Resmål, resans längd och syfte med resan ska framgå.
https://www.nano.lu.se/sites/nano.lu.se/files/nanolund_policy_research_visits_2.pdf - 2026-07-03
Background: A unique feature of alveolar mast cells is their low high-affinity IgE receptor (FcεRI) expression. Recent discoveries in uncontrolled asthma suggest that the appearance of FcεRI-expressing alveolar mast cells may be a novel disease-specific feature of allergic asthma. This study investigates whether increased FcεRI-expressing alveolar mast cells are present in patients with mild alle
The incidence of prostate cancer has increased dramatically during the last 10-15 years and it is now the commonest cancer in males in developed countries. The increase is mainly caused by the increasing use of opportunistic screening or case-finding based on the use of prostate-specific antigen (PSA) testing in serum. With this approach, prostate cancer is detected 5-10 years before giving rise t
The gene for an IgA-binding protein from a group A streptococcal strain was cloned and expressed in Escherichia coli. The IgA-binding protein, called protein Arp, was purified on IgA-Sepharose, allowing complete purification in a single step. Analysis of protein Arp by Western immunoblotting demonstrated a major IgA-binding band, with an apparent molecular weight of 42 kD. The purified protein was
Microsoft Word - PASANTIAS ESTUDIANTILES AUTOFINANCIADAS[1].doc PASANTIAS ESTUDIANTILES AUTOFINANCIADAS Generalidades. - Confirmar la especialidad o especialidades en que desea hacer su rotación, así como la fecha y número de semanas en cada rotación, lo cual no podrá ser menor de 2 semanas en cada una. -Se realizan en idioma español. -Las actividades son asesoradas y controladas por nuestros Prof
https://www.student.med.lu.se/sites/student.med.lu.se/files/2021-09/information-klinisk-placering-kuba.pdf - 2026-07-03
MYANMAR NATIONAL LAW AND POLICY REPORT CONSULTATION DRAFT 2020 Displacement in the Context of Disasters and Climate Change Funded by This report was prepared by Victor Bernard (RWI) 2020 TABLE OF CONTENTS 1 INTRODUCTION 1 1.1. A human rights-based approach 1 2 Displacement in Numbers 3 3 Recommendations from Human Rights Monitoring Bodies 5 4 Legal and Policy Framework 12 1 1 INTRODUCTION As refle
https://rwi.lu.se/wp-content/uploads/2024/03/Consultation-Draft_Myanmar.pdf - 2026-07-03
