Filetype
Group B Streptococcus (GBS) is a leading cause of invasive bacterial infections in human newborns. A key GBS virulence factor is its capsular polysaccharide (CPS), displaying terminal sialic acid (Sia) residues which block deposition and activation of complement on the bacterial surface. We recently demonstrated that GBS Sia can bind human CD33-related Sia-recognizing immunoglobulin (Ig) superfami
Regular prophylactic treatment with factor VIII (FVIII) and factor IX (FIX) concentrates in hemophilia A and B, respectively, is introduced in early infancy and has resulted in dramatic improvement of the conditions. Recombinant FVIII and FIX concentrates have been available for > 25 years and have been modified and refined through the years; however, unfortunately frequent intravenous administrat
Angiogenesis is a hallmark of cancer and is now a validated therapeutic target in the clinical setting. Despite the initial success, anti-angiogenic compounds impinging on the vascular endothelial growth factor (VEGF) pathway display limited survival benefits in patients and resistance often develops due to activation of alternative pathways. Thus, finding and validating new targets is highly warr
EndoS from Streptococcus pyogenes efficiently hydrolyzes the functionally important and conserved N-linked glycan of IgG in human blood. Repeated i.v. administration of EndoS in rabbits completely hydrolyzes the glycans of the whole IgG pool, despite the generation of anti-EndoS antibodies. EndoS administration had no apparent effects on the health of the animals. EndoS hydrolysis of the IgG glyca
Protein ADP-ribosylation is a reversible post-translational modification that regulates important cellular functions. The identification of modified proteins has proven challenging and has mainly been achieved via enrichment methodologies. Random mutagenesis was used here to develop an engineered Af1521 ADP-ribose binding macro domain protein with 1000-fold increased affinity towards ADP-ribose. T
Lymphocytes from human peripheral blood were separated by Countercurrent distribution (CCD) in a charged aqueous two-phase system composed of Dextran T 500 and polyethylene glycol 6000. Maximal responses to the T-cell mitogens phytohemagglutinin and concanavalin A were detected in a part of the distribution corresponding to the area where the highest percentage of E rosetting cells were seen. Anti
We have characterized 2 distinct mechanisms through which infectious agents may promote platelet adhesion and thrombus formation in flowing blood, thus contributing to the progression of disease. In one case, the process initiates when the integrin alpha(IIb)beta(3) mediates platelet arrest onto immobilized bacterial constituents that have bound plasma fibrinogen. If blood contains antibodies agai
CFEWP47 CFE Working paper series No. 47 Effective Judicial Protection of Individuals A duty for the Court of Justice or the National Courts? Cecilia Sjöstrand CFE Working papers are available at the website of the Centre for European Studies www.cfe.lu.se 2 Centre for European Studies at Lund University: Box 201: Phone +46 (0)46-222 88 19 SE-221 00 LUND Fax: +46 (0)46-222 32 11 Sweden E-mail: cfe@
https://www.cfe.lu.se/en/sites/cfe.lu.se.en/files/2020-12/cfewp47.pdf - 2026-07-03
In this short podcast, we define ageism and describe how it is quietly pervasive in our everyday lives. We discuss the negative impacts of ageism, provide examples, and identify ways to combat ageism. Target audience: high school/secondary school students. Music and mixing by Sean Mac.En este breve podcast, hablamos sobre el edadismo o discriminación por edad y describimos cómo está silenciosament
Tidplan-DESS-Rigg_250422.xlsx C:\Hardeberga Energiteknik AB\Kunder\Ecergy\P2308 LTH HP-rigg\04 Planering\Tidplan-DESS-Rigg_250422.xlsx DESS-Rigg - Återställning 2024-2025 Anders Dahl 2025-04-22 Projektresurser LTH Jens, Christer, Anders O Anm: "Driftsättning-kall" pausas för Montage kassetter samt tryckkärl (tunga lyft) Ecergy Anders Dahl Afry Tara Sabzevari Leverantörer Bricon, APQ-el, Rörläggare
https://www.energy.lth.se/sv/sites/energy.lth.se.sv/files/2025-05/Tidplan_DESS_2024-2025_250422.pdf - 2026-07-03
Background: A significant proportion of patients with asthma have persistent symptoms despite treatment with inhaled glucocorticosteroids. Objective: We hypothesized that in these patients, the alveolar parenchyma is subjected to mast cell-associated alterations. Methods: Bronchial and transbronchial biopsies from healthy controls (n = 8), patients with allergic rhinitis (n = 8), and patients with
Accomodation in Lund Hotels in Lund can be found through the home page of Visit Lund: http://www2.visitlund.se/en/accommodation There are of course also other booking sites that list hotels in Lund, such as e.g. hotels.com or booking.com. If you have problems finding a hotel room via the links provided above, you can also try go directly to Hotel Finn, where rooms have been pre-reserved for the co
https://www.msf.lu.se/sites/msf.lu.se/files/accomodation_in_lund_v2.pdf - 2026-07-03
Hun kaster hænderne op over ansigtet, kniber øjnene sammen og åbner munden i et lydløst skrig. Vinden tager fat i hendes fletninger, hendes nederdel. Jag stod på en stor klippa, jag brukade stå på den här klippan och låtsas att det var en scen. Och så var jag liksom på väg ner från klippan för jag tänkte att nu är det slut, men så när jag nästan var helt nere så ångrade jag mig och sprang upp i
https://www.thm.lu.se/loop-glommer-du-sa-husker-jeg-olivia-klang-och-mie-kristensen - 2026-07-01
