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Designing a system for computer aided diagnosis is a complex procedure requiring an understanding of the biology of the disease, insight into hospital workflow and awareness of available technical solutions. This paper aims to show that a valuable system can be designed for diagnosing kidney lesions in children and adolescents from 99m Tc-DMSA scintigraphy images. We present the chain of analysis
Time-resolved medical data has important applications in a large variety of medical applications. In this paper we study automatic analysis of dynamical renal scintigraphies. The traditional analysis pipeline for dynamical renal scintigraphies is to use manual or semiautomatic methods for segmentation of pixels into physical compartments, extract their corresponding time-activity curves and then c
Functional analysis of quantitative expression data is becoming common practice within the proteomics and transcriptomics fields; however, a gold standard for this type of analysis has yet not emerged. To grasp the systemic changes in biological systems, efficient and robust methods are needed for data analysis following expression regulation experiments. We discuss several conceptual and practica
Hormone-mediated maternal effects may be an important mechanism for adjusting offspring phenotype to particular requirements of the environment. We manipulated the levels of testosterone and androstenedione in the yolk of collared flycatcher Ficedula albicollis eggs to investigate the effects of pre-natal exposure to androgens on growth and immune function. Androgen treatment tended to reduce the
Background. Reliable risk estimates for venous thrombosis in families with inherited thrombophilia are scarce but necessary for determining optimal screening and treatment policies. Objectives: In the present analysis, we determined the risk of a first venous thrombotic event in carriers of a thrombophilic defect (i.e. antithrombin-, protein C- or protein S deficiency, or factor V Leiden). Patient
Traditional industrial robots have problems interacting with an uncalibrated, ill-defined environment where part geometry and position may vary. Active force control technology has therefore been suggested as a solution to add the extra sensory dimension needed to handle manufacturing tasks like assembly and deburring. The technology is proposed to give increased flexibility compared to other solu
What is the computational complexity of geometric model estimation in the presence of noise and outliers? We show that the number of outliers can be minimized in polynomial time with respect to the number of measurements, although exponential in the model dimension. Moreover, for a large class of problems, we prove that the statistically more desirable truncated L2-norm can be optimized with the s
In this paper we investigate whether learners of L2 English show knowledge of the Definiteness Effect (Milsark, 1977), which restricts definite expressions from appearing in the existential there-insertion construction. There are cross-linguistic differences in how restrictions on definiteness play out. In English, definite expressions may not occur in either affirmative or negative existentials (
In this paper, we revisit the classical perspective-n-point (PnP) problem, and propose the first non-iterative O(n) solution that is fast, generally applicable and globally optimal. Our basic idea is to formulate the PnP problem into a functional minimization problem and retrieve all its stationary points by using the Gr¨obner basis technique. The novelty lies in a non-unit quaternion representati
In this chapter a system for tracking the motion of box jellyfish Tripedalia cystophora in a special test setup is investigated. The goal is to measure the motor response of the animal given certain visual stimuli. The approach is based on tracking the special sensory structures - the rhopalia - of the box jellyfish from high-speed video sequences. The focus has been on a real-time system with sim
The top layer of a road is made up of a mixture of stones and bitumen and the durability is dependent on how well the bitumen adheres to the stones. The standard way of determining the bitumen coverage in the industry is the so called rolling bottle method, where a number of stones cov- ered with bitumen are put in a rolling bottle and the bitu- men coverage is estimated after different times. Thi
Distribute white and black hats in a dark room to a group of three rational players with each player having a fifty-fifty chance of receiving a hat of one colour or the other. Clearly, the chance that, as a result of this distribution, (A) "Not all hats are of the same colour" is 3/4. The light is switched on and all players can see the hats of the other persons, but not the colour of their own ha
In this demo we will show how devices from different vendors, using different protocols, can be combined and made to work together without detailed low-level programming by the user. The small example we have chosen uses a radio-controlled power socket from one vendor and a temperature sensor from another vendor. We use these to create a remotely controlled electric kettle, which keeps the water a
Application of cellulolytic enzymes for upgrading of secondary fibers has extensively been studied during the last decades. In many cases, research has been carried out with industrial enzyme preparations which often consist of several enzyme components. The presence of various enzymes makes the determination of the role of each of them difficult in changes of pulp and paper properties. Therefore,
In an attempt to identify subtypes of breast cancer and pinpoint patterns of cell cycle regulatory defects associated with clinical behaviour, proliferation and other transformation associated events, a multitude of cell cycle regulatory proteins were analysed in a material of 113 primary breast cancers. Increased proliferation was observed in two different scenarios; (1) with high cyclin D1 and e
Fibrin gel structure has been shown to be dependent on the thrombin concentration as well as the rate of thrombin generation. Accordingly, factor VIII (FVIII)and FIX-deficient plasma (hemophilia A and B) form loose fibrin clots with high permeability constants. By adding rFVIIa in vitro to FVIII-deficient plasma containing platelets (frozen and thawed), the fibrin gel permeability constant normali
Popular Abstract in English The concern about pollutant emissions from combustion devices has stimulated the development of modern combustion devices. As one of the major power generation machines, modern gas turbine engine has been designed to run at fuel-lean and premixed mode of combustion in which the combustion temperature is moderate so that NOx emission is low. Combustion in premixed mode rThis thesis deals with the physics of turbulent swirling flows. Large eddy simulation (LES) method is used to investigate the vortex breakdown process, the precessing vortex core (PVC), and the effect of swirl number and flow field configuration on swirling flows. The study is based on an open source CFD code, \textit{OpenFoam}. Turbulent swirling flows are widely used in combustion devices such a
The most used pavement for paved roads in the world is asphalt. It is therefore important that the asphalt is as durable as possible to avoid expensive repairs of the roads. One important factor of the durability of the road is the adherence between the stones and the bitumen that holds the stones together. The affinity is tested by the so called rolling bottle test, where one put stones covered i
The human antibody response to the conserved neutralization-related site on the gp 116 of human cytomegalovirus (HCMV) was investigated in healthy blood donors by the use of synthetic peptides. Anti-HCMV positive sera investigated in ELISA gave a reactivity of 48-56% with the peptide T7-13 (amino acids (aa) 67-86). Though epitope mapping revealed several individual fine specificities within this r
