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We explored the role of the Krebs cycle enzyme fumarate hydratase (FH) in glucose-stimulated insulin secretion (GSIS). Mice lacking Fh1 in pancreatic β cells (Fh1βKO mice) appear normal for 6–8 weeks but then develop progressive glucose intolerance and diabetes. Glucose tolerance is rescued by expression of mitochondrial or cytosolic FH but not by deletion of Hif1α or Nrf2. Progressive hyperglycem

Världen är föränderlig. För att kunna överleva måste allt liv kunna anpassa sig till rådande förhållanden. För cellen, livets minsta enhet, sker detta bland annat genom reglering av produktionstakten av proteiner, vilka är de molekyler som utför de flesta grundläggande funktioner. En speciell klass av proteiner utgörs av så kallade transkriptionsfaktorer. Dessa slår av eller på en gens produktion

The UNESCO Post-2015 Development Agenda proposes equitable quality education and lifelong learning for all as its overarching goals for education. A holistic quality approach is espoused to encourage lifelong learning and thereby build inclusive, sustainable, and prosperous societies. Their quality goals are particularly ambitious given that the practical recommendations for inclusive education ne

This paper will investigate the strategic design decision-making of an in-house designer in a company with a large product portfolio, with respect to how designers plan for future visual alterations of the product. In-house designers have to think strategically about the creation of recognition and differentiation through design because they influence the company's overall strategies. Therefore, w

The UN High Level Panel has called for a data revolution. The world’s population should be counted, measured, weighed, and evaluated. This information should be collected, compiled, aggregated, and presented in such a form that it can usefully inform policy-makers and citizens in aggregated forms, and disaggregated according to region, village, gender, and population group. It is tempting to think

The study of pragmatic markers attracts many scholars within the field of pragmatics, in particular in the area of radical pragmatics. Pragmatic markers are often perceived by speakers as having vague meanings that are hard to pin down in words. A pragmatic marker marker also often seem to contribute in different ways to the explicit or implicit message that the speaker wants to convey depending o

Within clay prone areas it is important to know if and to what extent quick clay is present. In Sweden undisturbed sampling and laboratory investigations are used to determine clay sensitivity and identify quick clay. Recent research for mapping of quick clay areas with the resistivity method is based on the fact that low pore-water salinity constitutes a criterion for quick clay formation. Electr

Vertebral augmentation is among the current standards of care to reduce pain in patients with vertebral fractures (VF), yet a lack of consensus regarding efficacy and safety of percutaneous vertebroplasty and kyphoplasty raises questions on what basis clinicians should choose one therapy over another. Given the lack of consensus in the field, the American Society for Bone and Mineral Research (ASB

“Home” has become a commercialised place in contemporary Sweden. As both cause and ef- fect of this development, the Swedish market for furniture and interior decoration has grown significantly during the last twenty years. Retailers, television shows and magazines have con- tributed to a steadily progressing market, where consumers shop for the latest in furniture as well as the latest ideas and

There existed a great ambivalence concerning masculinity and its relationship to religion in the decades around the last turn of the century. The historical encoding process of religion, from gender neutral to feminine, have in general been interpreted as something solely negative for the constitution of masculinity during this period. Consequently, religious encoded masculinities have been deemed

Centre for Environmental and Climate Research, 2014-10-16 CEC support to write research applications Summary CEC supports the writing of application for external grants by associated researchers to carry out environmental and climate research. This support ranges from help with practicalities when writing individual research applications to financial support to arrange meetings and coordinating th

https://www.cec.lu.se/sites/cec.lu.se/files/cec_support_to_write_research_applications_final20141016.pdf - 2026-07-10

LL_SMMS10_prel160829 Reading list for Service Management: Theory – Development and Traditions, 15 hp, SMMS10. The reading list was approved by the Board of the Department of Service Management and Service Studies 29 August, 2016. The reading list is valid from 29 August 2016. Literature – part one of the course (about 1250 pp.)   1.   Choose among one of these four textbooks on making a literature

https://www.ses.lu.se/en/sites/ses.lu.se.en/files/ll_smms10_prel160829.pdf - 2026-07-10

S L U T R A P P O R T Lunds universitet Institutionen för strategisk kommunikation Forskningsprojektet Kommunikativa organisationer Mats Heide, Charlotte Simonsson, Howard Nothhaft, Rickard Andersson & Sara von Platen Den kommunikativa organisationen d e n k o m m u n i k a t i v a o r g a n i s a t i o n e n 2 Utgivare: Sveriges Kommunikatörer, Stockholm ISBN 978-91-519-0404-7 © Författarna 2018

https://www.isk.lu.se/sites/isk.lu.se/files/slutrapport_den_kommunikativa_organisationen_no2.pdf - 2026-07-10

https://www.luaccommodation.lu.se/sites/luaccommodation.lu.se/files/2023-03/Cleaning%20checklist.docx - 2026-07-10

The Centre for East and South- East Asian Studies Work Report 2018 LUND UNIVERSITY | CENTRE FOR EAST AND SOUTH-EAST ASIAN STUDIES 2 CENTRE FOR EAST AND SOUTH-EAST ASIAN STUDIES WORK REPORT • 2018 Work Report 2018 for the Centre for East and South-East Asian Studies ADMINISTRATION AND ORGANISATION During 2018 the Centre for East and Southeast Asian Studies was engaged in preparations for the organi

https://www.ace.lu.se/sites/ace.lu.se/files/work_report_2018.pdf - 2026-07-10

Utbildningsplan Kandidatprogram i personal- och arbetslivsfrågor Faculty of Fine and Performing Arts Bachelor of Fine Arts programme, 180 credits KGFKO, Konstnärligt kandidatprogram i fri konst, 180 högskolepoäng First-cycle degree programme not requiring previous university study/Program utan akademiska förkunskapskrav och med slutlig examen på grundnivå Details of approval The syllabus was appro

https://www.khm.lu.se/en/sites/khm.lu.se.en/files/utbildningsplan_kandidat_final_20191220_eng_.pdf - 2026-07-10