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The main objective was to study the effect on progression-free survival (PFS) of adding erlotinib to bevacizumab as maintenance treatment following chemotherapy and bevacizumab as first-line treatment of metastatic colorectal cancer (mCRC).

Background: Cancer-related fatigue is a common problem in persons with cancer, influencing health-related quality of life and causing a considerable challenge to society. Current evidence supports the beneficial effects of physical exercise in reducing fatigue, but the results across studies are not consistent, especially in terms of exercise intensity. It is also unclear whether use of behaviour

This paper is part a project studying the problem “How is globalization perceived and conceptualized”? Approaching this problem, my contribution to the project aims at an analysis of some of the publications of the British Muslim organization The Islamic Foundation.A preliminary analysis of the publications suggests the usefulness of a globalization perspective. However, since the perceptions and This paper is part a project studying the problem “How is globalization perceived and conceptualized”? Approaching this problem, my contribution to the project aims at an analysis of some of the publications of the British Muslim organization The Islamic Foundation.A preliminary analysis of the publications suggests the usefulness of a globalization perspective. However, since the perceptions and

The production of W boson pairs in proton-proton collisions at s=8 TeV is studied using data corresponding to 20.3 fb−1 of integrated luminosity collected by the ATLAS detector during 2012 at the CERN Large Hadron Collider. The W bosons are reconstructed using their leptonic decays into electrons or muons and neutrinos. Events with reconstructed jets are not included in the candidate event sample.

Peripheral artery disease affects >200 million people worldwide and is associated with significant limb and cardiovascular morbidity and mortality. Limb revascularization is recommended to improve function and quality of life for symptomatic patients with peripheral artery disease with intermittent claudication who have not responded to medical treatment. For patients with critical limb ischemia,

Stress-related disorders are a frequent cause for sick leave, with consequences such as great distress and adverse economic effects for the affected person and substantial costs for society. Identifying effective interventions that facilitate return to work is thus important. The aim of this study was to evaluate the effectiveness of the 16-week Redesigning Daily Occupations program as a work reha

Cardiovascular dysfunction is common after out-of-hospital cardiac arrest as part of the postcardiac arrest syndrome, and hypothermia may pose additional impact on hemodynamics. The aim was to investigate systemic vascular resistance index (SVRI), cardiac index, and myocardial performance at a targeted temperature management of 33°C (TTM33) versus 36°C (TTM36).

The advanced research that is being carried out in different science fields today requires advanced technologies; for the study of distant places and hidden elements of our universe tools like The Hubble Telescope, Voyager 2 and the Very Large Array has been to great use. In the same way, a neutron source and its instruments enable scientist to see and understand basic atomic structures and forces.

The recognition of honor-related violence has been emphasized in the media and through legal regulation during the last decades in Sweden. Honor oppression is often characterized by its cultural/religious roots and is found in patriarchal and collective societies. However, the regulations might have stigmatizing effects as they target certain communities in society. Previous research shows that ho

This thesis is a critical, feminist ethnographic research of one of the most extremist and violent movements that originated from the growing online anti-feminist ideology. Based on a feminist poststructuralist epistemological tradition, this thesis researches the growing Incel movement through feminist cyber-ethnography, netnography and feminist content analysis. The analysis bases on a dataset o

The purpose of this thesis is to display our results received from the assignment GfK addressed to us. GfK is an independent part who aid companies when they need statistical assistance. In order to forecast sales for one of GfK’s customers we have build models with time series analysis. We received 26 products with monthly data from 2005 to 2008. In this thesis we have narrowed it down to six of

A directional crack growth prediction in a compressed homogenous elastic isotropic material under plane strain conditions is considered. The conditions at the parent crack tip are evaluated for a straight stationary crack. Remote load is a combined biaxial compressive normal stress and pure shear. Crack surfaces are assumed to be frictionless and to remain closed during the kink formation whereforA directional crack growth prediction in a compressed homogenous elastic isotropic material under plane strain conditions is considered. The conditions at the parent crack tip are evaluated for a straight stationary crack. Remote load is a combined biaxial compressive normal stress and pure shear. Crack surfaces are assumed to be frictionless and to remain closed during the kink formation wherefor

Objective: To identify clinical and histopathological risk factors of LNM in T1 CRC. Summary of Background Data: The requisite of additional surgery after locally resected T1 CRC is dependent on the risk of LNM. Depth of submucosal invasion is used as a key predictor of lymphatic metastases although data are conflicting on its actual impact. Methods: Retrospective population-based cohort study on

BACKGROUND: In the European Union alone, more than 100 million people present to the emergency department (ED) each year, and this has increased steadily year-on-year by 2-3%. Better patient management decisions have the potential to reduce ED crowding, the number of diagnostic tests, the use of inpatient beds, and healthcare costs.METHODS: We have established the Skåne Emergency Medicine (SEM) co

Background: Targeted temperature management at 33 °C (TTM33) has been employed in effort to mitigate brain injury in unconscious survivors of out-of-hospital cardiac arrest (OHCA). Current guidelines recommend prevention of fever, not excluding TTM33. The main objective of this study was to investigate if TTM33 is associated with mortality in patients with vasopressor support on admission after OH

π Men hosts a transiting planet detected by the Transiting Exoplanet Survey Satellite space mission and an outer planet in a 5.7 yr orbit discovered by radial velocity (RV) surveys. We studied this system using new RV measurements taken with the HARPS spectrograph on ESO's 3.6 m telescope, as well as archival data. We constrain the stellar RV semiamplitude due to the transiting planet, π Men c, as

Objectives Evaluate the natural course of anterior cruciate ligament (ACL) healing on MRI within 5 years of acute ACL rupture and compare 2-year and 5-year outcomes based on healing status and treatment group. Methods Secondary analysis of 120 Knee Anterior Cruciate Ligament Nonsurgical vs Surgical Treatment (KANON) trial participants randomised to rehabilitation and optional delayed ACL reconstru

Background Several researchers have argued that disturbances in embodiment play an important role in the development of psychological health problems among adolescents. The purpose of the present study was to use the 12-item Embodiment Scale (ES-12), with its three subscales Harmonious Body (HB), Disharmonious Body (DB), and Body for Others (BO), (1) to identify subgroups of adolescents with diffe

BACKGROUND AND OBJECTIVE: There is no standardized regimen for follow-up after radical cystectomy (RC) for bladder cancer (BC). To address this gap, we conducted a multicenter study involving urologist members from the European Association of Urology (EAU) bladder cancer guideline panels. Our objective was to identify consistent post-RC follow-up strategies and develop a practice-based framework b