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The EU-US Privacy Shield Regime for Cross-Border Transfers of Personal Data under the GDPR: What are the legal challenges and how might these affect cloud-based technologies, big data, and AI in the medical sector?

Cloud-based technologies, big data, statistical signal processing algorithms, and Artificial Intelligence (AI) technologies are expected to play an increasingly important role in themedical field. Big data and AI-technologies rely on the cloud for data storage as well as for computational power and thus need effective and robust legal frameworks for international data transfer. Because of inconsis

Energy issues in sustainable urban wastewater management : Use, demand reduction and recovery in the urban water cycle

Urban water systems and, in particular, wastewater treatment facilities are among the major energy consumers at municipal level worldwide. Estimates indicate that on average these facilities alone may require about 1% to 3% of the total electric energy output of a country, representing a significant fraction of municipal energy bills. Specific power consumption of state-of-the-art facilities shoul

An exploration of occupational choices in adolescence : A constructivist grounded theory study

Background: Adolescence is a critical period within the life course, for developing adult occupational competencies and health behaviours. Few studies have considered how 16–17 year olds choose activities and behaviours from an occupational perspective. Aim and objectives: To explore how adolescents aged 16–17 years old make choices about their daily occupations to inform a theoretical model of oc

A general model of dissonance reduction: unifying past accounts via an emotion regulation perspective

Cognitive dissonance has been studied for more than 60 years and many insightful findings have come from this research. However, some important theoretical and methodological issues are yet to be resolved, particularly regarding dissonance reduction. In this paper, we place dissonance theory in the larger framework of appraisal theories of emotion, emotion regulation, and coping. The basic premise

Differential fitness effects of moonlight on plumage colour morphs in barn owls

The Moon cycle exposes nocturnal life to variation in environmental light. However, whether moonlight shapes the fitness of nocturnal species with distinct colour variants remains unknown. Combining data from long-term monitoring, high-resolution global positioning system tracking and experiments using prey, we show that barn owls (Tyto alba) with distinct plumage colourations are differently affe

PEAK3/C19orf35 pseudokinase, a new NFK3 kinase family member, inhibits CrkII through dimerization

Members of the New Kinase Family 3 (NKF3), PEAK1/SgK269 and Pragmin/SgK223 pseudokinases, have emerged as important regulators of cell motility and cancer progression. Here, we demonstrate that C19orf35 (PEAK3), a newly identified member of the NKF3 family, is a kinase-like protein evolutionarily conserved across mammals and birds and a regulator of cell motility. In contrast to its family members

A Detailed Observational Analysis of V1324 Sco, the Most Gamma-Ray-luminous Classical Nova to Date

It has recently been discovered that some, if not all, classical novae emit GeV gamma-rays during outburst, but the mechanisms involved in the production ofgamma-rays are still not well understood. We present here a comprehensive multiwavelength data set - from radio to X-rays - for the most gamma-ray-luminous classical nova to date, V1324 Sco. Using this data set, we show that V1324 Sco is a cano

The contribution of the ARIEL space mission to the study of planetary formation

The study of extrasolar planets and of the Solar System provides complementary pieces of the mosaic represented by the process of planetary formation. Exoplanets are essential to fully grasp the huge diversity of outcomes that planetary formation and the subsequent evolution of the planetary systems can produce. The orbital and basic physical data we currently possess for the bulk of the exoplanet

Mi'kmaq Landscapes : From Animism to Sacred Ecology

This book seeks to explore historical changes in the lifeworld of the Mi'kmaq Indians of Eastern Canada. The Mi'kmaq culture hero Kluskap serves as a key persona in discussing issues such as traditions, changing conceptions of land, and human-environmental relations. In order not to depict Mi'kmaq culture as timeless, two important periods in its history are examined. Within the first period, betw

Family members’ experiences of waiting in intensive care : a concept analysis

Aim: The aim of this study was to explore the meaning of family members’ experience of waiting in an intensive care context using Rodgers’ evolutionary method of concept analysis. Method: Systematic searches in CINAHL and PubMed retrieved 38 articles which illustrated the waiting experienced by family members in an intensive care context. Rodgers’ evolutionary method of concept analysis was applie

How complex are galaxies? A non-parametric estimation of the intrinsic dimensionality of wide-band photometric data

Galaxies are complex objects, yet the number of independent parameters to describe them remains unknown. We present here a non-parametric method to estimate the intrinsic dimensionality of large data sets. We apply it to wide-band photometric data drawn from the COSMOS2020 catalogue and a comparable mock catalogue from the HORIZON-AGN simulation. Our galaxy catalogues are limited in signal-to-nois

Genomic characterization of the HER2-enriched intrinsic molecular subtype in primary ER-positive HER2-negative breast cancer

ER-positive/HER2-negative (ERpHER2n) breast cancer classified as PAM50 HER2-enriched (ERpHER2n-HER2E) represents a small high-risk patient subgroup. In this study, we investigate genomic, transcriptomic, and clinical features of ERpHER2n-HER2E breast tumors using two primary ERpHER2n cohorts comprising a total of 5640 patients. We show that ERpHER2n-HER2E tumors exhibit aggressive clinical feature

Modelling wood moisture content in outdoor conditions from measured data

Sustainable use of wood requires an understanding of expected service life, particularly when the material is exposed to outdoor conditions and, thus, fungal decay. Since moisture is the primary vector for fungal decay, accurate moisture prediction is a key component in service life assessment. For this purpose, the present study leverages existing measured data for linear regression of in-field m

Memory and Identity in the Emotive Map of Alain Resnais’ Hiroshima Mon Amour (1959)

The focus of this article is Alain Resnais’ representation of collective and individual memory and identity in Hiroshima Mon Amour (1959). The film is based on Marguerite Duras’ script from 1958 and remains faithful to this original text. With partial reference to Giuliana Bruno’s views on imaginary cities and urban cartography, the screened urban space will here be read as an emotive map in which

Should Benzodiazepines be Used for Reducing Dyspnea in Patients with Advanced Illnesses?

Dyspnea is a common and highly distressing symptom in patients with advanced illnesses. Many patients continue to experience chronic dyspnea despite optimal management of underlying disease(s) and various non-pharmacologic interventions, necessitating the consideration of pharmacologic therapies for palliation of dyspnea. One commonly asked question by clinicians is whether benzodiazepines have a