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Your search for "what do you do on the dark web 【Visit Sig8.com】9ZP42K8.5R9I" yielded 90483 hits

Environmental spaces : a geopolitics of environmental interdependence in the Baltic Sea area

Using the development of intergovernmental environmental cooperation in the Baltic Sea area as a concrete example, the aim of this study is to explore how the ‘environ- ment’ in situations of environmental interdependence is identified and institutional- ised as political-geographical objects. ‘Environmental interdependence’ is to this end conceptualised as a tension between ‘political spaces’ of

Solvatochromism of dye-labeled dendronized polymers of generation numbers 1–4: comparison to dendrimers

Two series of dendronized polymers (DPs) of generations g = 1–4 with different levels of dendritic substitution (low and high) and a solvatochromic probe at g = 1 level are used to study their swelling behavior in a collection of solvents largely differing in polarity as indicated by the Kamlet–Taft parameters. This is done by measuring the UV-Vis spectra of all samples in all solvents and determi

Reptile embryos lack the opportunity to thermoregulate by moving within the egg

Historically, egg-bound reptile embryos were thought to passively thermoconform to the nest environment. However, recent observations of thermal taxis by embryos of multiple reptile species have led to the widely discussed hypothesis that embryos behaviorally thermoregulate. Because temperature affects development, such thermoregulation could allow embryos to control their fate far more than histo

Thermo-economic study on the implementation of steam turbine concepts for flexible operation on a direct steam generation solar tower power plant

Among concentrating solar power technologies, direct steam generation solar tower power plants represent a promising option. These systems eliminate the usage of heat transfer fluids allowing for the power block to be run at greater operating temperatures and therefore further increasing the thermal efficiency of the power cycle. On the other hand, the current state of the art of these systems doe

Persistent changes in striatal gene expression induced by long-term L-DOPA treatment in a rat model of Parkinson's disease

Current knowledge of the molecular changes induced by dopamine denervation and subsequent treatment with L-DOPA is based on studies performed on relatively acute and young animal models of parkinsonism. It is highly warranted to ask how well these models simulate the state of chronic denervation and sustained L-DOPA pharmacotherapy which are typical of advanced Parkinson's disease. This study inve

Circular Business Model Framework : Mapping value creation architectures along the product lifecycle

Circular business models are foreseen to contribute to enabling prolonged lifetimes of products and components through successive cycles of reuse, repair, remanufacturing and closing material loops. To realize economic viability and resource efficiency savings from a circular business model, early consideration and integrated planning of the product lifecycle and value creation architectures at th

Improved molecular recognition of Carbonic Anhydrase IX by polypeptide conjugation to acetazolamide

The small molecule inhibitor acetazolamide (AZM) was conjugated to a set of designed polypeptides and the resulting conjugates were evaluated for their affinity to Human Carbonic Anhydrase II (HCA II) using surface plasmon resonance. The dissociation constant of the AZM-HCA II complex was 38. nM and that of the AZM conjugated polypeptide (4-C10L17-AZM) to HCA II was found to be 4. nM, an affinity

Transformed Readings : Negotiations of Cult in Paul, Hebrews, and First Clement

Issues surrounding relationships between different writings and questions regarding literary dependence are ubiquitous in New Testament scholarship. This study aims to answer questions concerning how one is to understand the way that early Christian writers used other Christian writings: Are any typical characteristics discernible regarding the earliest use of Christian writings? Were they memoriz

Islet amyloid polypeptide and calcitonin gene-related peptide expression are down-regulated in dorsal root ganglia upon sciatic nerve transection

Islet amyloid polypeptide (IAPP) is structurally related to calcitonin gene-related peptide (CGRP) and has been implicated in glucose homeostasis and diabetes pathogenesis because it is expressed in insulin cells and forms amyloid in pancreatic islets from type II diabetic patients. IAPP is also constitutively co-expressed with CGRP in rat sensory neurons. Whether expression of IAPP is altered by

Paleoredox and pyritization of soft-bodied fossils in the ordovician frankfort shale of New York

Multiple beds in the Frankfort Shale (Upper Ordovician, New York State), including the original "Beecher's Trilobite Bed," yield fossils with pyritized soft-tissues. A bed-by-bed geochemical and sedimentological analysis was carried out to test previous models of soft-tissue pyritization by investigating environmental, depositional and diagenetic conditions in beds with and without soft-tissue pre

Post-Deleuzian Investigations of U.S. Avant-Garde Film, 1943–81

The aim of this dissertation is to investigate a number of U.S. avant-garde films using Deleuzian film-philosophy in order to describe their thought. I develop the taxonomy of cinematic images created by the French philosopher Gilles Deleuze by introducing a new type of image. The notion of the sobjective image I conceptualize points to the immanent semiosis that characterizes certain films. The s

Stadsbor : urbana aktörer, subjektiv interaktionism och social neurovetenskap i tidigmedeltidens Sigtuna och Nyköping

In Swedish historical archaeology, studies of towns have diverged from definition to deconstruction. In landscape studies the existence of occasional similar expressions of power in rural contexts as in towns is stressed. Another observation is that towns can display vague forms of urbanity, with lack of dense settlement and varied economy, as well as showing agrarian affiliations. A focus on sing

Circulating fetuin - A and risk of type 2 diabetes : A mendelian randomization analysis

Fetuin-A, a hepatic-origin protein, is strongly positively associated with risk of type 2 diabetes in human observational studies, but it is unknown whether this association is causal. We aimed to study the potential causal relation of circulating fetuin-A to risk of type 2 diabetes in a Mendelian randomization study with single nucleotide polymorphisms located in the fetuin-A–encoding AHSG gene.

Benchmark ages for the Gaia benchmark stars

In the era of large-scale surveys of stars in the MilkyWay, stellar ages are crucial for studying the evolution of the Galaxy.But determining ages of field stars is notoriously difficult; therefore, we attempt to determine benchmark ages for the extensively studied Gaia benchmark stars which can be used for validation purposes. By searching the literature for age estimates from different methods a

Diffusion and Concentration of Solids in the Dead Zone of a Protoplanetary Disk

The streaming instability is a promising mechanism to drive the formation of planetesimals in protoplanetary disks. To trigger this process, it has been argued that sedimentation of solids onto the mid-plane needs to be efficient, and therefore that a quiescent gaseous environment is required. It is often suggested that dead-zone or disk-wind structure created by non-ideal magnetohydrodynamical (M

Coagulation factor VIII is vital for increasing global coagulation after physical exercise

Background: In a previous smaller study, we found evidence of a diminished global coagulation capacity after maximal exercise in patients with severe haemophilia A (HA). Aim: To validate these results, we repeated the study in a larger cohort. We also examined if the exercise-induced increased levels of von Willebrand factor (VWF) might prolong the effect of factor concentrate administered just be