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Supply chain management and early involvement of suppliers into product development process is one of the key elements of concurrent engineering. Internet based Product Lifecycle Management (PLM) system can improve communication between customers and suppliers. In the case study is presented a communication model and configuration of the PLM system that supports a second tier system supplier in au

The proliferative activity of aging hematopoietic stem cells (HSCs) is controversially discussed. Inducible fluorescent histone 2B fusion protein (H2B-FP) transgenic mice are important tools for tracking the mitotic history of murine HSCs in label dilution experiments. A recent study proposed that primitive HSCs symmetrically divide only four times to then enter permanent quiescence. We observed t

The system of welcoming newly arrived students in Sweden has experienced numerous modifications since its inception. Additionally, because the interpretation of education laws us left to the municipalities and head teachers, the various policies have resulted in a multitude of local practices. Over the years, a very wide range of models for organising newcomer reception have therefore been tried o

An open challenge is the reliable dimensioning of polymer gears due to the lack of accurate data on the fatigue strength of polymer materials, and the complex relations between geometric and operating parameters. The national standards (BS 6168:1987, JIS B 1759:2013) and the guidelines of the German engineering association VDI 2736 are available for the calculation of polymer gears. In most cases,

Eleven patients with acute myelogenous leukemia (AML) in the acute stage of the disease were studied. Sera of seven patients were assayed for complement‐dependent cytotoxicity to autochthonous AML cells and sera of four patients were tested with allogeneic target cells before and after ultrafiltration at low pH. No specific cytotoxic activity could be detected in any untreated sera. Ultrafiltratio

Current levels of global warming (Haustein et al. 2017) have already intensified heat waves, droughts, and floods, with many recent events exhibiting evidence of being exacerbated by anthropogenic climate change (e.g., Herring et al. 2016, 2018). Recent improvements in understanding demonstrate that half a degree of additional warming will have further severe impacts (Masson-Delmotte et al. 2018).

Many contemporary scholars have recently defended the idea that the agency of things is symmetrical and equivalent to human agency. We propose an alternative approach to artefacts’ agency based on a field study concerned with contextually situated observations of the process of design of artefacts in Amazonia. By means of participant observation and interviews, we address the role of artefacts in

The city of Moscow has been going through a transformation of its surface transport network during the past decade as part of a broader policy of urban beautification. Despite a renewed interest in public transport, this policy has led to the dismantling of the trolleybus system. This was met with resistance from various groups. Bringing together scholarly discussions on urban growth coalitions an

Quantitative measurements of blood flow based on magnetic resonance imaging (MRI) using conventional multiple spin echo sequences were evalutated in vivo in healthy young volunteers. Blood flow was measured using MRI in the femoral vein. The initial slope of the multiple spin echo decay curve, corrected for the T2 decay of non-flowing blood was used to calculate the blood flow. As a reference, the

A classroom guide to teaching the case, “The Swedish Academy #MeToo Scandal and the Reputation of the Nobel Prize” (HBS No. 5-919-410). A fictional case protagonist must present his evaluation to the Nobel Foundation of the scandal affecting one of the Nobel independent network members and its implications for the Foundation. Key issues include the reputational effects of the Swedish Academy scand

This Letter presents the first direct investigation of the p–Σ0 interaction, using the femtoscopy technique in high-multiplicity pp collisions at s=13 TeV measured by the ALICE detector. The Σ0 is reconstructed via the decay channel to Λγ, and the subsequent decay of Λ to pπ−. The photon is detected via the conversion in material to e+e− pairs exploiting the capability of the ALICE detector to mea

The magnitude and ecological impact of climate change varies with latitude. Several recent models have shown that tropical ectotherms face the greatest risk from warming because they currently experience temperatures much closer to their physiological optimum than temperate taxa. Even a small increase in temperature may thus result in steep fitness declines in tropical species but increased fitnes

Prostate cancer is the second most common cause of cancer-related deaths in men, representing a major source of morbidity and mortality. Androgen deprivation therapy is the primary treatment for patients with advanced prostate cancer at disease presentation, which can be achieved either with surgical or chemical castration. The development of gonadotropin-releasing hormone agonists revolutionized

The existing information supports the use of this material as described in this safety assessment. Decanoic acid was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data on the target material and from read-across analog nonanoic acid (CAS # 112-05-0) show that dec

The eastern part of the Svalbard archipelago and the adjacent areas of the Barents Sea were subject to extensive erosion during the Late Weichselian glaciation. Small remnants of older sediment successions have been preserved on Edgeoya, whereas a more complete succession on Kongsoya contains sediments from two different ice-free periods, both probably older than the Early Weichselian. I

Previous research indicates that exporting firms are willing to pay a premium to poach workers from other exporting firms if experience working for an internationally engaged firm reduces trade costs. Since international experience is less valuable to non-exporters, we would expect to see differences in recruitments between firms that are internationally engaged and those that serve only their dom

Male-only parental care, while rare in most animals, is a widespread strategy within teleost fish. The costs and benefits to males of acting as sole carer are highly variable among fish species making it challenging to determine the selective pressures driving the evolution of male-only care to such a high prevalence. We conducted a phylogenetic meta-analysis to examine the costs and benefits of p