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Malignant astrocytomas are the most common primary tumors of the adult central nervous system. Surgical resection of tumor mass in combination with radiotherapy and chemotherapy is only palliative and there is a clear need for new and more effective therapeutic strategies. The aim of this study was to develop a dendritic cell (DC)-based vaccine for the treatment of experimental brain tumors with
Popular Abstract in Swedish Bostäder med särskild service som upplevs ge möjlighet till socialt umgänge, avskildhet och återhämtning har positiva effekter på livskvaliteten hos människor med psykisk funktionsnedsättning. Vidare visar resultaten från denna avhandling att den visuella upplevelsen av miljön och upplevelsen av hemlikhet är betydelsefulla för att etablera en stödjande atmosfär. Boendem
Popular Abstract in Swedish Denna avhandling behandlar strömlinjeformade subglaciala bäddformer (ofta kallade drumliner) i södra Sverige. Det övergripande syftet med denna studie är att bidra till en lösning av det så kallade ”drumlinproblemet”. Termen drumlin har kommit att tillämpas på en grupp av landformer vars interna sediment, strukturella uppbyggnad och yttre form kan variera kraftigt. DessThis thesis investigates stream-lined subglacial bedforms (often referred to as drumlins) in southern Sweden. The broad aim of this is to contribute to the solution of the ‘drumlin problem’. The term drumlin has come to be applied to a wide range of features whose internal architecture (core) and overall morphology are seen to vary greatly. This range in characteristics is in part responsible for
The aim of this article is to offer an object lesson in how historians could make use of feature film as primary source material if they were to use the analytical tools developed in the field of film studies and by historians who started to work with film in the 1970s and 1980s. My own work on representations of maidservants in Swedish feature films in the 1930s and 1940s is used as a case in poi
Background: Macrophage migration inhibitory factor (MIF) has been proposed to play a detrimental role in stroke. We recently showed that MIF promotes neuronal death and aggravates neurological deficits during the first week after experimental stroke, in mice. Since MIF regulates tissue inflammation, we studied the putative role of MIF in post-stroke inflammation. Methods: We subjected C57BL/6 mice
An internal tandem duplication of FLT3 (FLT3/ITD) occurs in approximately 25% of newly diagnosed AML. PKC412 inhibits the growth of leukemic cell lines with FLT3 mutations such as the MV4-11. This study evaluated the in vitro effects of the combination of PKC412 and ara-C or daunorubicin, studying the effect of co-incubation, pre-incubation and sequential incubation of the drugs in patient samples
Converging evidence indicates that women with pregnancy-associated breast cancer (PABC) have increased mortality compared to women with breast cancer not diagnosed near pregnancy (non-PABC). Our aim was to investigate if the stage distribution differs between PABC and non-PABC and if stage at diagnosis can explain the poorer prognosis observed among women with PABC. We identified 3,282 breast canc
Water scarcity is one of the environmental issues, which societies face nowadays. The demand for water in popular tourist destinations, in areas that are already subject to limited natural water resources, compounds the problem. Therefore, the objective of the present study was to examine whether social marketing can be an effective method to increase the reuse rates of towels in hotels. The chose
Socio-economic rights have been described as the ''underdeveloped stepchild of the human rights family''. There has been a tendency to treat them as merely aspirational and it is frequently argued that they may not deserve the name of rights as they lack content and are considered ill-suited for enforcement. Owing to this, and because of the fact that their enjoyment has by their v
The fruit fly Drosophila melanogaster has a well-studied olfactory system. A crucial part of the olfactory system is the olfactory sensory neurons (OSNs). One type of these OSNs, Ab3a, expresses the Odor receptors (ORs) Or22a and Or22b. Or22a is known to play an important role for behaviors like oviposition, but no strong ligand has been found for Or22b. Recent studies have shown that D. melanogas
Otillåten andrahandsuthyrning och oskäliga andrahandshyror är ett omfattande problem i Sverige. Förstahandshyresgäster upplåter sina lägenheter utan tillstånd och tar ut alldeles för höga hyror. Problemet har uppmärksammats av Justitiedepartementet, som i februari 2017 tillsatte en utredningskommitté med uppdraget att se över om gällande hyreslagstiftning kräver ändringar för att motverka uttag avUnlawful subletting and unjustifiable rents are widespread problems in Sweden. Tenants sublet their rental apartments without landlords’ permission and charge subtenants too high rental levels. The issue has drawn the attention of the Swedish Ministry of Justice, which in February 2017 appointed a committee to investigate whether decreasing unlawful subletting motivated by lucrative profits requir
Tvistebenägenheten rörande ABK 09 har de senaste 15 åren ökat. Rättspraxis på området är begränsat men med den ökade tvistebenägenheten så kommer ABK 09 bli än viktigare att behärska. Syftet med denna uppsats är att undersöka och bringa klarhet till ABK 09 kap. 8 § 1. Bestämmelsen reglerar beställarens hävningsrätt. Uppsatsen fokuserar på meningen i paragrafens andra stycke konsulten har rätt tilThe tendency to litigate regarding ABK 09 has increased over the past 15 years. Case law in the area is limited but with increased litigations the ABK 09 will be more important to master. The purpose of this study is to examine and clarify ABK 09 chapter 8 article 1. The provision regulate the clients right to cancel the contract. The main focus of this study is in the sentence of the second para
Sedan 1993 äger svensk polis rätt att använda de så kallade öppna tvångsmedlen husrannsakan, beslag, kroppsvisitation och kroppsbesiktning när det föreligger misstanke om ringa narkotikabrott. Integritetsskyddskommittén vittnade år 2007 om att Justitieombudsmannen och Justitiekanslern varje år får ta emot flera klagomål kring användningen av dessa tvångsmedel. Med anledning av detta ställer uppsatThe Swedish Police Authority has since 1993 the right to use a number of coercive measures when faced with a suspected case of petty drug offense. The measures permitted to be used by the police in these cases are search, seizure, personal body search and intimate search. In 2007 a parliamentary committee stated that a number of reports of irregular use of the coercive measures had been received b
Due to rapid developments in communication technology, it is likely that 5G networks will be rolled out in 2019. To adapt to 5G, hardware will have to develop to meet the requirements of this new technology. The mmWave communication is one of the main elements of 5G technology. The mmWave frequency bandwidth is used to carry the data links and can achieve a higher transmission data rate than the
In the following report, a fire safety evaluation of Hotel Nissastigen in central Gislaved is presented. The building itself consists of five floors, whereof two are cellar and attic. Beyond the usual hotel business, Nissastigen both offers a place to eat at their restaurant and room for conferences, as well as acting as a gathering point for tourists, thus making it vital for the local economy.
Anthropogenic use of nitrogen and phosphorus causes a risk to aquatic ecosystems and hence the livelihood of humans. To tackle this issue, the European Union have imposed environmental obligations on its member states to higher the quality of the aquatic environment. As a member state, Denmark is partly fulfilling these objectives by re-creating wetlands in the landscape, which retain and remove n
Economic inequality is growing rapidly worldwide. Despite research showing that higher inequality within a society corresponds with a higher rate of public health and social problems, there exist little organized resistance against the neo-liberal economic policies that allow the super-rich to pull away from the rest of the population. Even though the causes of poverty cannot be separated from the
Sammanfattning Grundtanken med aktiebolag som bolagsform är att den ekonomiska risken inte ska överstiga insatt kapital. Det finns i aktiebolagslagen ingen direkt koppling mellan bolagets företrädare och bolaget som är en egen juridisk person. Men det finns situationer som gör att bolagets företrädare kan bli personligt betalningsansvarig för bolagets förpliktelser, ett så kallat medansvar. UppsaSummary The basic idea of the limited company corporate form is that the financial risk should not exceed the invested capital. It is available in the companies act no direct linkbetween the company's representatives and the company, which is a separate legal entity. But there are situations that will allow the company's representative can be personally liable for the company's obliga
