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A Systematic Characterization of Aquaporin-9 Expression in Human Normal and Pathological Tissues

AQP9 is known to facilitate hepatocyte glycerol uptake. Murine AQP9 protein expression has been verified in liver, skin, epididymis, epidermis and neuronal cells using knockout mice. Further expression sites have been reported in humans. We aimed to verify AQP9 expression in a large set of human normal organs, different cancer types, rheumatoid arthritis synovial biopsies as well as in cell lines

Lane-deviation penalty formulation and analysis for autonomous vehicle avoidance maneuvers

Autonomous vehicles hold promise for increased vehicle and traffic safety, and there are several developments in the field where one example is an avoidance maneuver. There it is dangerous for the vehicle to be in the opposing lane, but it is safe to drive in the original lane again after the obstacle. To capture this basic observation, a lane-deviation penalty (LDP) objective function is devised.

A shrine for the nation : The material transformation of the Lovćen site in Montenegro

Mount Lovćen holds significant cultural, political and religious symbolism in Montenegro, especially due to the fact that the mountain is the last resting place of the prince-bishop and national poet Petar II Petrovich-Njegoš (1813–1851). In the twentieth century the grave of Njegoš has undergone profound material transformations. Each of these transformations has led to heated debates about the s

Whose vision is it anyway? The “free internet” in Chinese state media

This study seeks to explain how Chinese state media bolster the use of visions in global internet governance. The empirical data for the article consists of 1,158 internet related articles published in the Global Times between 2009 and 2018. I develop a theoretical perspective that distinguishes between grand and strategic narratives. Based on a mixed-methods approach, I show that “internet sovere

Evolution of P-wave indices during long-term follow-up as markers of atrial substrate progression in arrhythmogenic right ventricular cardiomyopathy

AIMS: Patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) have increased prevalence of atrial arrhythmias indicating atrial involvement in the disease. We aimed to assess the long-term evolution of P-wave indices as electrocardiographic (ECG) markers of atrial substrate during ARVC progression. METHODS AND RESULTS: We included 100 patients with a definite ARVC diagnosis according

Tumor‐associated humoral cytotoxicity in patients with acute myelogenous leukemia before and after chemotherapy

Sera of eight unselected adult patients with acute myelogenous leukemia obtained before and after chemotherapy were repeatedly tested for specific complement‐dependent cytotoxicity against autochthonous peripheral white blood cells from the acute leukemia stage and from the remission stage, respectively. Complement‐dependent cytotoxicity against white blood cells from the acute leukemia stage was

Influence of Socio-Economic Factors and Region of Birth on the Risk of Preeclampsia in Sweden

Objectives: To investigate the association between socio-economic factors and the risk of preeclampsia in Sweden, specifically investigating if this relationship is confounded by maternal region of birth. Study design: All singleton births between 1999 and 2009 in an ethnically diverse area in southern Sweden, totaling 46,618 pregnancies, were included in this study. The data on maternal pregnancy

The symplectic geometry of higher Auslander algebras: Symmetric products of disks

We show that the perfect derived categories of Iyama’s d-dimensional Auslander algebras of type A are equivalent to the partially wrapped Fukaya categories of the d-fold symmetric product of the 2-dimensional unit disk with finitely many stops on its boundary. Furthermore, we observe that Koszul duality provides an equivalence between the partially wrapped Fukaya categories associated to the d-fol

High-energy and ultra-high-energy neutrinos: A Snowmass white paper

Astrophysical neutrinos are excellent probes of astroparticle physics and high-energy physics. With energies far beyond solar, supernovae, atmospheric, and accelerator neutrinos, high-energy and ultra-high-energy neutrinos probe fundamental physics from the TeV scale to the EeV scale and beyond. They are sensitive to physics both within and beyond the Standard Model through their production mechan