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Background: The clinical management of pancreatic and other periampullary neoplasms remains challenging. In contrast to other cancer types, immunotherapies are largely ineffective, and the reason for the deprived immune response and the immune inhibiting cellular composition is only fragmentarily understood. The aim of this study was to comprehensively map the abundance, topographic distribution a
The study explored to what extent dreams have been perceived as being helpful in waking life. More specifically, for "important" waking life (conscious) decisionmaking, the solving of emotional or nonemotional (practical/technical/work-related) problems, forming/changing an attitude about something or somebody, or a conscious behavioral change of the dreamer (N = 667). On a general level, 62,1% of
The higher vibrational levels of the C 1s→π* excitation in carbon monooxide (CO) were investigated by using resonant Auger electron spectroscopy. The absorption profile of the CO was recorded in the partial electron yield mode. The results showed that the vibrational states were not seen in a total yield absorption spectrum whereas they were shown to be discernable in a partial electron yield spec
Individual differences in cognitive performance increase with advancing age, reflecting marked cognitive changes in some individuals along with little or no change in others. Genetic and lifestyle factors are assumed to influence cognitive performance in ageing by affecting the magnitude and extent of age-related brain changes (i.e., brain maintenance or atrophy), as well as the ability to recruit
International Journal of Molecular Medicine ISSN 1107-3756
Aim: To assess growth plate fusion by magnetic resonance imaging (MRI) and evaluate the correlation with sex, age, pubertal development, physical activity and BMI. Methods: Wrist, knee and ankle of 958 healthy subjects aged 14.0-21.5 years old were examined using MRI and graded by two radiologists. Correlations of growth plate fusion score with age, pubertal development, physical activity and BMI
We study the organic aerosol (OA) budget in a tropical forest by analyzing a case that is representative for the OP3 campaign at Borneo. A model is designed that combines the essential dynamical and chemical processes that drive the diurnal evolution of reactants in the atmospheric boundary layer (BL). In this way, the model simultaneously represents the effects and interactions of various dynamic
This article presents a political and legal analysis of the emergency brake in criminal law in Articles 82(3) and 83(3) TFEU. It suggests that the emergency brake offers a powerful discretionary prerogative for Member States seeking to protect the integrity of their criminal justice systems. This strong legal shield for Member States in the form of a ‘quasi-veto’ is contrasted with a tendency to d
Adiabatic laminar burning velocities and post-flame NO mole fractions for neat and blended ethanol and n-heptane premixed flames were experimentally determined using a heat flux burner and laser-induced fluorescence. The flames were stabilized at atmospheric pressure and at an initial temperature of 338 K, over equivalence ratios ranging from 0.6 to 1.5. These experiments are essential for the dev
Ungulate prey can use increased vigilance to reduce their risk of predation, but little is known of the combined and interactive risk effects from humans and wolves in determining ungulate behaviour across time and space. Understanding the interplay between these risk effects is increasingly important, considering the recolonisation of several large carnivores to more human-dominated landscapes in
Rationale: Hypercapnia develops in one third of patients with advanced chronic obstructive pulmonary disease (COPD) and is associated with increased morbidity and mortality. Multiple factors in COPD are thought to contribute to the development of hypercapnia including increased carbon dioxide (CO2) production, increased dead space ventilation, and the complex interactions of deranged respiratory s
Osteoarthritis (OA) constitutes a major and increasing burden on patients, health care systems and the broader society. It is estimated that around a quarter of the adult population is affected by OA in the knee and hip and that the prevalence of OA will increase over the coming decades largely due to aging and adverse life-style factors. Prevention and effective care are critical to manage the ch
How blood parasite infections influence the migration of hosts remains a lively debated issue as past studies found negative, positive, or no response to infections. This particularly applies to small birds, for which monitoring of detailed migration behavior over a whole annual cycle has been technically unachievable so far. Here, we investigate how bird migration is influenced by parasite infect
