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Popular Abstract in Swedish Bakgrund: Diabetes är en sjukdom som karakteriseras av kroniskt förhöjt blodsocker och som obehandlad kan leda till svåra komplikationer i blodkärl, ögon, njurar, nerver m.m. Sjukdomen beror på kroppens oförmåga att producera (typ 1 diabetes) eller svara på effekt av (typ 2 diabetes) hormonet insulin. Det finns ca 150 miljoner personer med diabetes i världen idag, och sType 2 diabetes is characterised by defects in insulin sensitivity, insulin secretion and increased endogenous glucose production. The relative contribution of each of these defects remains controversial. In order to characterise the metabolic defects in various stages of glucose tolerance, the insulin sensitivity and insulin secretion was measured in a large population based study in Finland and

Popular Abstract in Swedish Avhandlingen handlar om lärares tankar om kompetensutveckling med utgångspunkt i intervjuer med olika lärare vid tre tillfällen under 1990-talet. Lärare utvecklar i lärarutbildning allmänna lärarkunskaper, ämneskunskaper och ämnesdidaktiska kunskaper under 3,5 - 5,5 år, beroende på elevernas åldrar och lärarens ämneskombinationer. I yrkesverksamheten deltar lärare i ettThe development in society and school activities that have taken place during the past twenty years, form the background to the problem in this thesis. Liberal democratisation in the society as a whole and the global explosion of knowledge have made it necessary for teachers continuously to develop new knowledge. The over all aim of the thesis concerned the development of knowledge of variations

Popular Abstract in Swedish POPULÄRVETENSKAPLIG SAMMANFATTNING IMMUNFÖRSVARET OCH KOMPLEMENTSYSTEMET Till skydd mot infektioner har människan sitt immunförsvar. Här ingår till exempel vita blodkroppar och en mängd olika proteiner. En viktig grupp av proteiner kallas för komplementsystemet, vilket består av ca 30 proteiner som kan angripa bakterier och andra oönskade partiklar och delta i för-störThe ability of many pathogenic microorganisms to cause infection is dependent on their ability to evade attack by the complement system of the host. One mechanism by which microorganisms may avoid complement attack is to bind complement inhibitory molecules present in the host. This thesis describes studies of the complement inhibitor C4BP and of inter-actions between C4BP and the human pathogen

Popular Abstract in Swedish Hur kan nattaktiva insekter se i mörker med fel sorts ögon? Majoriteten av alla dagaktiva insekter har en sorts facettöga som kallas appositionsöga. Appositionsögon är anpassade till ett liv med god tillgång på ljus ? nattaktiva djur har därför i princip alltid andra sorters ögon (superpositionsögon). Anledningen till att appositionsögon fungerar bäst på dagen är att dDue to our own preference for bright light, we tend to forget that many insects are active in very dim light. The reasons for nocturnal activity are most easily seen in tropical areas of the world, where animals face severe competition for food and nocturnal insects are able to forage in a climate of reduced competition and predation. Generally nocturnal insects possess superposition compound eye

Popular Abstract in Swedish Vissa E. coli bakterier kan vara utrustad med arvsanlag (gener) som kodar för vidhäftningsfaktorer, som gör att den kan binda till tarmslemhinnan, eller toxiner som kan orsaka olika typer av tarmsjukdom som diarré. En annan faktorer som kan bidra till att en bakterie kan orsaka infektion är genkassetter, som kodar för en rad av olika gener, som t.ex för upptag av järn, The presence of genes in food, encoding some virulence factors, was studied by PCR, and species of Enterobacteriaceae, associated with food, were studied by the DNA-based methods of TTGE, ribotyping and sequencing. The flora of fresh and chill-stored pork were analysed by a culture-independent approach, using specific amplification of 16S rRNA genes followed by cloning and sequencing. No evidence

Popular Abstract in Swedish Sammanfattning Mänskliga aktiviteter och klimatförändringar påverkar vegetationen över hela jorden, idag och i framtiden. Denna påverkan kan studeras och kvantifieras med hjälp av observationer från satelliter vilka förmedlar information om vegetationsförändringar i tid och rum. I denna doktorsavhandling har metoder för analys av vegetationsförändringar utvecklats och Abstract This thesis aims to advance the analysis of nonlinear trends in time series of vegetation data from Earth observation satellite sensors. This is accomplished by developing fast, efficient methods suitable for large volumes of data. A set of methods, tools, and a framework are developed and verified using data from regions containing vegetation change hotspots. First, a polynomial-fittin

Popular Abstract in Swedish Vid hjärtsvikt är hjärtats pumpförmåga nedsatt och kroppens vävnader kan ej förses med tillräckligt mycket blod utan kompensatoriska förändringar i kroppen. Dessa kompensationsmekanismer är kortvarigt ändamålsenliga men skjuter snabbt över målet vid hjärtsvikt och förvärrar istället symptomen. Under de senaste åren har behandlingen av hjärtsvikt därför kommit att inriktAngiotensin-converting enzyme (ACE) inhibitors act by decreasing production of angiotensin II and by potentiating the effects of bradykinin by inhibition of its breakdown. Bradykinin exerts part of its effects via vasodilating prostaglandins. Since the cyclooxygenase (COX)-inhibitors, e.g. aspirin and non-steroidal anti-inflammatory drugs, NSAIDs, block the formation of prostaglandins patients may

The performance of eight fast-response methane (CH4) gas analysers suitable for eddy covariance flux measurements were tested at a grassland site near the Cabauw tall tower (Netherlands) during June 2012. The instruments were positioned close to each other in order to minimise the effect of varying turbulent conditions. The moderate CH4 fluxes observed at the location, of the order of 25 nmol m(-2

The oral contraceptive pill is associated with a modest increase in the risk of early-onset breast cancer in the general population, but it is possible that the risk is higher in certain subgroups of women. The relative risk of breast cancer associated with oral contraceptive use has been reported to be higher for African-American women than for white women. African-American women also have a high

This review paper focuses on modelling of wastewater treatment plants (WWTP). White-box modelling is widely applied in this field, with learning, design and process optimisation as the main applications. The introduction of the ASM model family by the IWA task group was of great importance, providing researchers and practitioners with a standardised set of basis models. This paper introduces the n

In this prospective study, the 10- and 15-year incidence and course of retinopathy were examined in relation to medical risk indicators from 3.1 +/- 1.9 (mean -/+ SD) years diabetes duration and onwards in 29 adult type 1 diabetic patients treated under routine care. A total of 28 patients were followed for 10 years and 20 patients for 15 years diabetes duration. After 10 years diabetes duration,

Marker-based studies of inbreeding may lead to an enhanced understanding of inbreeding depression in natural populations, which is a major concern in conservation genetics. Correlations between marker heterozygosity and variation in fitness-associated traits—‘heterozygosityfitness correlations’ (HFCs)—are of particular importance and have been widely applied in natural populations. In partially in

Popular Abstract in Swedish Pankreascancer (cancer i bukspottkörteln) utgör fjärde orsak död i cancer. Det är den cancerform som har den dystraste prognosen av alla, med en 5-års överlevnad mindre än 6%. Sjukdomsrelaterade symptom uppträder ofta sent i förloppet och det saknas metoder för tidig diagnos varför de flesta av patienterna upptäckts i sent skede. Endast cirka 20 procent av patienterna k

1. In a correlative study, we investigated the relative importance of fish predation, refuge availability and resource supply in determining the abundance and size distributions of the introduced and omnivorous signal crayfish (Pacifastacus leniusculus) in lakes and streams. Moreover, the biomass and food selection of predatory fish was estimated in each habitat type and stable isotopes of carbon

1. To investigate further the release, localization and identity of a non-nitrergic mediator of smooth muscle relaxation in the female pig urethra, we studied the effects of drugs acting at alpha 2-adrenoceptors or K+ channels, the effects of capsaicin and chemical sympathectomy, and the actions of several transmitter candidates. 2. Electrical field stimulation (EFS; frequencies above 12 Hz) of sp

Popular Abstract in Swedish Syftet med studien har varit att, genom huvudsakligen kvalitativ beskrivning, studera narrativ sekvens, d v s berättelsen, i exolingvala samtal mellan infödd och icke infödd (svensktalande studenter) talare av franska. Den teoretiska ramen sträcker sig från textlingvistik (Revaz, Adam, Bronckart etc.) till konversationsanalys (Labov, Sacks, Norrick, Laforest, Kerbrat-OrThe aim of this study is to examine, through a mainly qualitative description, the narrative in exolingual conversations in French between non-native speakers (NNS) (Swedish students) and native speakers (NS). The theoretical frame ranges from text linguistics (Revaz, Adam, Bronckart etc.) to conversation analysis (Labov, Sacks, Norrick, Laforest, Kerbrat-Orecchioni, Bres, Norrby etc.). The study

Popular Abstract in Swedish Något tillspetsat förefaller varje kommun driva utvecklingsarbete inriktat på verksamhetsmått. Är så inte fallet är ansvariga snabba att betona att verksamhetsmått är viktigt och att de precis har beslutat om ett större måttprojekt. Denna bok ger en bild av i vilken omfattning fyra gatukontor utformar och använder verksamhetsmått. Boken innehåller också beskrivningar ocThe purpose of this study is to develop a frame of reference within which formal control system performance measures can be described and their design and use can be analyzed for control systems in municipalities. From a cybernetic control approach measures are used as instruments to plan and gain feedback from employee actions, and adjust them to the internal and external environment of which the

Popular Abstract in Swedish Syftet med avhandlingen är att studera relationen mellan ekonomisk knapphet och konsumtion med fokus på barnfamiljer. Avhandlingen handlar huvudsakligen om att teoretiskt försöka förstå vad ekonomisk knapphet kan innebära i förhållande till ett konsumtions- eller överflödssamhälle som det svenska. Barnfamiljer används som ett empiriskt exempel för att illustrera de teorThe object of this thesis has been to study the relationship between consumption and economic scarcity from a theoretical perspective. I have used families with children as an empirical example to illustrate the theoretical framework. There are two main questions: The first focuses on the structures that create specific conditions for low-income consumers. The second relates to how the households

This is the first comprehensive monograph on the subject of the architect Fred Forbat. He was a pioneer of functionalism who worked in four different countries. Besides being a presentation of Forbats work, interesting in itself, this investigation also aims at addressing certain questions regarding the history and concept of functionalism as a style and movement. I deal with the work in chronolog

Background: Oral contraceptive use has been associated with an increase in the risk of breast cancer in young women. We examined whether this association is seen in women at high risk of breast cancer because they carry a mutation in one of two breast cancer susceptibility genes, BRCA1 and BRCA2. Methods: We performed a matched case-control study on 1311 pairs of women with known deleterious BRCA1