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Novel peptide ligand with high binding capacity for antibody purification

Small synthetic ligands for protein purification have become increasingly interesting with the growing need for cheap chromatographic materials for protein purification and especially for the purification of monoclonal antibodies (mAbs). Today, Protein A-based chromatographic resins are the most commonly used capture step in mAb down stream processing; however, the use of Protein A chromatography

Äldre personers sista tid i livet. Livskvalitet, vård, omsorg och närståendes situation.

The aim of this thesis was to investigate old people's care and quality of life during the last period of life, but also to investigate their own and next-of-kin's experience of this phase. The thesis is based on four studies using separate samples. The sample (n=1198) in study I was drawn from the care and services part of the sub-study ?Good Aging in Skåne? (GAS). The criteria for inclusion in s

Heme Protein Biogenesis - Catalase in Enterococcus faecalis

Heme proteins form a large and diverse group of proteins which are involved in a variety of biological functions. The heme prosthetic group enables them to carry out redox reactions, transport electrons, bind gaseous molecules, and function as sensors. Despite their importance only little is generally known about heme protein biogenesis. The Gram-positive bacterium Enterococcus faecalis is found i

Hybrid renewable energy systems for remote locations

Many locations in Indonesia such as small islands and remote villages on the main islands are not connected to the main electricity grid, and may never be as they are too remote for grid extensions to be economically justifiable. Therefore, many either do not have electricity or are dependent on expensive diesel transports to fuel their stand alone, diesel powered mini-grids. Using a hybrid renewa

Image-Based Partial-Volume Correction in SPECT: Application to 177Lu radionuclide therapy

Introduction and aim: In SPECT imaging, the finite spatial resolution of the imaging system leads to a blurring of the reconstructed image. Consequently, counts originating from each point in the source distribution will be spread out over a volume in the reconstructed image, leading to spill-over of counts between different structures and distortion of the apparent activity concentration. This pr

Feathers by day, membranes by night - Aerodynamic performance in bird and bat flight

The efficiency and performance of a flying animal is directly related to the aerodynamics around its body and flapping wings. Here, I have developed methods for quantifying the wake dynamics around a flying animal. The results are used to estimate the aerodynamic performance of flapping flight. Using these methods, I have studied flight of the Pied Flycatcher (Ficedula hypoleuca), the Pallas’ Long

Treatment Preferences for Acute Allergic Reactions : A Discrete Choice Experiment

Background: Timely treatment of acute allergic reactions (AARs) is important to minimize reaction severity. Corticosteroid tablets dissolved in water are commonly used in mainstay treatment. A new oral film that dissolves on the tongue provides a faster and less cumbersome alternative to tablets for corticosteroid administration during AARs. This study evaluated patients' preferences for attribute

Dairy Consumption, Lactase Persistence, and Mortality Risk in a Cohort From Southern Sweden

Background: Whether high dairy consumption is related to longevity is still unclear, and additional studies of prospective cohorts with high-quality dietary data from populations with wide consumption ranges are needed. Objective: To examine the association between dairy consumption and mortality in a Swedish cohort. Design: Among 26,190 participants (62% females, 45-73 years old) without diabetes

Nordic gore : Strangers, foreigners & the communities we imagine for ourselves

The idea of a Nordic community, even though it was a reality in the past and is still a quite tangible idea in the present – because all Nordic countries have striking similarities – is often obscured by the more recent idea that the nation always comes first, and for quite some time now the Nordic countries have been anxious to set themselves apart from their closest neighbour in particular.In th