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Polarization transfer solid-state NMR for studying soft matter: From surfactants to the stratum corneum

The work presented in this thesis is dedicated to theoretical development, experimental testing and application of polarization transfer solid-state nuclear magnetic resonance (PT ssNMR). PT ssNMR is an analytical tool which provides detailed information about molecular mobility in model or simple soft matter systems at the low water content regime, enabling the creation of phase diagrams. Soft ma

Review of current study methods for VRU safety. Part 1 – Main report

The report presents the results of a review of the study methods related to vulnerable road user safety that are used today and aims to link accident causation factors to VRU accident risk. The review covered the following categories of study methods: epidemiological studies based on accident and injury data; in-depth accident investigations; naturalistic driving studies; behavioural observations;The report presents the results of a review of the study methods related to vulnerable road user safety that are used today and aims to link accident causation factors to VRU accident risk. The review covered the following categories of study methods: epidemiological studies based on accident and injury data; in-depth accident investigations; naturalistic driving studies; behavioural observations;

Exploring Unorthodox Aquaporins : Characterization of NbXIPs & AtNIPs

AbstractAquaporins are membrane integral proteins that facilitate the transport of waterand/or other small neutral molecules across biological membranes in cells in allforms of life. Among the subfamilies of aquaporins in higher plants, the X IntrinsicProteins (XIPs) are the most recently discovered subfamily and the leastcharacterized. However, the aromatic/arginine (ar/R) selectivity filter and

Sloth : The revelation of waste

Someone who throws away their rubbish on a street-corner or in a ditch is guilty of sloth. This may appear harmless, but seen through the lens of waste management, sloth soon develops into a deadly sin that harms other people’s lives and health. Hiding and forgetting waste has always been a practice with potentially disastrous consequences; buried containers full of toxins will eventually start to

Cryogels Based on Crosslinked Cells as Green Biocatalysts for Biotechnology

Popular Abstract in English Popular science Microbial cells are small and difficult to handle in industrial processes, especially if they are to be reused subsequent batches. In order to make them easier to handle, these cells can be attached to a solid support, by so-called immobilization. This provides particles of sizes that are easy to filter and reuse. However, immobilization is associated wiAbstract Due to the finite nature of fossil resources and their environmental impact, such as greenhouse gases and climate change, the bio-based production of chemicals, materials and fuels is the subject of extensive research in industrial biotechnology. Biotransformation and fermentation are considered to be mild, “green” processes that make use of effective and reliable biocatalysts to provide

Mechanisms for Acceleration of Halide Anation Reactions of Platinum(IV) Complexes. REOA versus Ligand Assistance and Platinu(II) Catalysis without Central Ion Exchange

Chloride anation of trans-Pt(CN)4ClOH2− has been studied with and without Pt(CN)42− present at 25.0°C by use of stopped-flow and conventional spectrophotometry and a 1.00 M perchlorate medium. The rate law in the absence of Pt(CN)42− is compatible with a chloride assistance via an intermediate of the type Cl-Cl-Pt(CN)4···OH22−, in which the reactivity of the aqua ligand is enhanced due to a partia

Holistic approach in engineering design - controlling risks from accidental hazards in bridge design

Engineering design, in concise terms, is what engineers do using what they know. It is the underlying decision making activity that determines what is to be built and how it should be built. An ever present requirement in engineering design is that the structure should be safe. While historical approaches to safety in design relied on experience and engineering judgment, modern approaches have rat

Metastatic Breast Cancer: Biomolecular Characterization and Targeted Therapy

Metastasis is a complex process that remains a major challenge in the clinical management of cancer, because most cancer-related deaths are attributed to disseminated disease rather than the primary tumor. Despite the significant advances in the prediction of prognosis, and therapeutic management of primary breast cancers, coupled with the substantial improvement in our understanding of the molecu