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Using direct manipulation for real-time structural design exploration

Det första skedet när ett byggnadsverk ska uppföras är det konceptuella designskedet, det är här de första besluten om utformningen av byggnadsverket görs. I det traditionella arbetsflödet utformas byggnadsverket först i ett ritprogram, sedan används ett annat datorverktyg för att verifiera att det utformade byggnadsverket kan hantera de krafter som uppstår, t.ex. vind, egentyngd osv. Detta arbeteBefore a new structure can be built, it must be designed. This design phase is a very important step in the building process. The total cost of the structure and its structural performance are largely dependent on the structural design process. The impact of decisions on the design process is initially high and declines as the design matures. However, few computational tools are available for the

Lunds-universitets-magasin-10-2004

LUM nr 10 - 2004 I Anslagens goda tider... Nya Medfak formerar sig Hotell- drömmar Hotell- drömmar L U N D S U N I V E R S I T E T M E D D E L A R - - - - - - - - - - - - - - - - N U M M E R 1 0 D E C 2 0 0 4 Å R G Å N G 3 7 Anslagens goda tider... Nya Medfak formerar sig II Lunds universitets tidskrift LUM utkom första gången 1968. Den når i dag samtliga anställda och nästan lika många utanför un

https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-10-2004.pdf - 2026-05-20

Sten k johnsonscenter jan2013

Sten K. Johnson Centre for Entrepreneurship För entreprenörer och morgondagens ledare Genom en donation på 20 miljoner kronor från industri­ mannen Sten K. Johnson lades grunden för den utbildnings­ och forskningsplattform som idag finns på centret. Vi har kunnat förstärka utbildningarnas kvalitet och rekrytera fler topp forskare. Nu är vi redo för nästa utvecklingssteg. Målet är tydligt: Vi ska b

https://www.lu.se/sites/www.lu.se/files/sten_k_johnsonscenter_jan2013.pdf - 2026-05-20

Ramos isabel

Introduction Lund University International Master’s Programme in Environmental Science Master Thesis How can Transfrontier Conservation Areas (TFCAs) Promote Sustainable Development? Isabel Maria Matos Dias Ramos isabelramos@yahoo.com Rua António Patrício 107 – 1º 4150 – 100 Porto / Portugal Phone : (++) 351 96 670 18 07 Thesis Advisor Åsa Mattsson asa.mattsson@svet.lu.se Political Science Departm

https://www.lumes.lu.se/sites/lumes.lu.se/files/ramos_isabel.pdf - 2026-05-20

Natural sugar as an MRI contrast agent for brain cancer detection using chemical exchange saturation transfer (CEST) imaging at 3T

Hjärntumörer utgör cirka 2,5% av alla cancerdiagnoser i Sverige (2013) och femårsöverlevnaden är cirka 50%. Hjärntumörer diagnostiseras med bildtagningstekniker såsom datortomografi (CT), positronemissionstomografi (PET) och magnetkamera (MR). En MR-bild byggs upp av signaler från protoner i vatten, som är en av människokroppens vanligaste beståndsdelar. För att möjliggöra diagnostisering och klasBackground and Purpose: Dynamic glucose-enhanced (DGE) imaging is a novel technique that can be used to assess information about microvasculature by using natural sugar (D-glucose) as a biodegradable contrast agent. The method relies on chemical exchange saturation transfer (CEST). The hydroxyl protons in glucose are saturated using a selective radio-frequent pulse and will subsequently exchange w

Cardiovascular events following coronavirus disease 2019 vaccination in adults : a nationwide Swedish study

Background and Aims. While the rationale for coronavirus disease 2019 (COVID-19) vaccination is to reduce complications and overall mortality, some cardiovascular complications from the vaccine itself have been demonstrated. Myocarditis and pericarditis are recognized as rare acute adverse events after mRNA vaccines in young males, while evidence regarding other cardiovascular events remains limit

A2030 monthly Update 230411

Agenda 2030 Graduate School monthly newsletter #3 2023-04-11 Ylva van Meeningen Hi! Hope that you all have/had a nice Easter, Ramadan or Pesach. Where I celebrated this year, the sun was shining and we saw the first butterfly of the season. There is an old superstition that you can tell how the summer is going to be like depending on what type of butterfly you see. I saw a lemon butterfly, which f

https://www.agenda2030graduateschool.lu.se/sites/agenda2030graduateschool.lu.se/files/2024-01/A2030_monthly%20update_230411.pdf - 2026-05-20

Vem tycker vad i utvecklingsprocessen av IFRS for SMEs?

Syftet med uppsatsen är att undersöka om åsikterna skiljer sig åt beroende på vilken geografisk region respondenten härstammar ifrån samt att undersöka om åsikterna skiljer sig åt mellan intressegrupperna. För att bearbeta materialet har en kvantitativ innehållsanalys gjorts av inkomna kommentarsbrev till IASB:s exposure draft 2013/9 för IFRS for SMEs som, utöver förslagen, innehöll åtta direkta

Publication in nat rev neurol

Cell-based therapies for Parkinson disease—past insights and future potential NATURE REVIEWS | NEUROLOGY ADVANCE ONLINE PUBLICATION | 1 John van Geest Centre for Brain Repair & Department of Neurology, Department of Clinical Neurosciences, University of Cambridge, Forvie Site, Cambridge CB2 0PY, UK (R.A.B.). Wallenberg Neuroscience Center, Division of Neurobiology and Lund Stem Cell Center, Lund U

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_nat_rev_neurol.pdf - 2026-05-20

Vbe politik web

VETENSKAP OCH BEPRÖVAD ERFARENHET POLITIK VETENSKAP OCH BEPRÖVAD ERFARENHET VID SBU | 3 2 | STEN ANTTILA & SUSANNA AXELSSON VETENSKAP OCH BEPRÖVAD ERFARENHET POLITIK Förord 9 NILS-ERIC SAHLIN Tro eller vetande – vilken plats i politiken? 19 BARBRO WESTERHOLM Faktaförnekaren – är han/hon ett hot mot demokratin? 29 FINN BENGTSSON Kunskaper och evidens i politiken 41 DANIEL TARSCHYS Evidensbasering i

https://www.vbe.lu.se/sites/vbe.lu.se/files/vbe_politik_web.pdf - 2026-05-20

Anomalous Salt Dependence Reveals an Interplay of Attractive and Repulsive Electrostatic Interactions in α-synuclein Fibril Formation

α-Synuclein (α-syn) is an intrinsically disordered protein with a highly asymmetric charge distribution, whose aggregation is linked to Parkinson’s disease. The effect of ionic strength was investigated at mildly acidic pH (5.5) in the presence of catalytic surfaces in the form of α-syn seeds or anionic lipid vesicles using thioflavin T fluorescence measurements. Similar trends were observed with

Spin propensity in resonant photoemission of transition metal complexes

Resonant photoelectron spectroscopy (RPES) has been used to probe electronic structure properties of the closed-shell [FeII(CN)6]4− and open-shell [FeIII(CN)6]3− prototype transition metal complexes in aqueous solution. Site-selective Fe 2p (L-edge) RPES mapsprovide new insight into spin-coupling processes at the core-excited metal centers, with autoionization of [FeIII(CN)6]3− showing a dramatic

Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

Background: Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding of these findings and hindering downstream translational efforts such as drug target discovery. Results: To expand our understanding of the underlying biological pathways and m

Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models

The application of multiple omics technologies in biomedical cohorts has the potential to reveal patient-level disease characteristics and individualized response to treatment. However, the scale and heterogeneous nature of multi-modal data makes integration and inference a non-trivial task. We developed a deep-learning-based framework, multi-omics variational autoencoders (MOVE), to integrate suc

The contribution of population age-sex structure to the excess mortality estimates of 2020–2021 in Denmark, Finland, Iceland, Norway, and Sweden

The Nordic countries offer an ideal case study of the COVID-19 pandemic due to their comparability, high data quality, and variable mitigations. We investigated the age- and sex-specific mortality patterns during 2020–2021 for the five Nordic countries and analysed the total age- and sex-adjusted excess deaths, ratios of actual to expected death rates, and age-standardized excess death estimates.

In vivo cortical glutathione response to oral fumarate therapy in relapsing-remitting multiple sclerosis : A single-arm open-label phase IV trial using 7-Tesla 1H MRS

BACKGROUND: This is an open-label, single-arm, single-center pilot study using 7-Tesla in vivo proton magnetic resonance spectroscopy (1H MRS) to measure brain cortical glutathione concentration at baseline before and during the use of oral fumarates as a disease-modifying therapy for multiple sclerosis. The primary endpoint of this research was the change in prefrontal cortex glutathione concentr

Parallel motion vision pathways in the brain of a tropical bee

Spatial orientation is a prerequisite for most behaviors. In insects, the underlying neural computations take place in the central complex (CX), the brain’s navigational center. In this region different streams of sensory information converge to enable context-dependent navigational decisions. Accordingly, a variety of CX input neurons deliver information about different navigation-relevant cues.

Effective interventions in preventing gestational diabetes mellitus: A systematic review and meta-analysis

Background: Lifestyle choices, metformin, and dietary supplements may prevent GDM, but the effect of intervention characteristics has not been identified. This review evaluated intervention characteristics to inform the implementation of GDM prevention interventions. Methods: Ovid, MEDLINE/PubMed, and EMBASE databases were searched. The Template for Intervention Description and Replication (TIDieR