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Basal Metabolic Requirements, Biomarkers of Cardiometabolic Health, and Anthropometric Measures of Obesity in Women and Men With Restricted Growth Conditions

Population-specific thresholds have not been defined for the levels of adiposity and systemic biomarkers that predict chronic health risks in people with restricted growth conditions. Here, anthropometric measures of adiposity, basal metabolic requirements, and fasted blood samples were obtained from adults with restricted growth (age 41 ± 14 years, height 1.30 ± 0.10 m, body mass 60.5 ± 18.3 kg,

Epidemiology, Characteristics, and Treatment Outcomes of Mycoplasma pneumoniae Pneumonia in Hospitalized Adults : A 5-Year Retrospective Cohort Study

Background This study aimed to describe the incidence rate, patient characteristics, treatments, and outcomes of adults hospitalized with Mycoplasma pneumoniae pneumonia. Methods This retrospective cohort study included adults diagnosed with M pneumoniae pneumonia and admitted to emergency care hospitals in Stockholm County, Sweden, from 2013 to 2017. Patients were identified through positive M pn

Endoscopic and Surgical Management of Non-Metastatic Ampullary Neuroendocrine Neoplasia : A Multi-Institutional Pancreas2000/EPC Study

Introduction: Ampullary neuroendocrine neoplasia (NEN) is rare and evidence regarding their management is scarce. This study aimed to describe clinicopathological features, management, and prognosis of ampullary NEN according to their endoscopic or surgical management. Methods: From a multi-institutional international database, patients treated with either endoscopic papillectomy (EP), transduoden

Grassland Butterfly Index - Bending the curve

1. Grassland is an important habitat for butterflies and many other pollinating insects. Over half of the 501 European butterflies use grasslands as one of their main habitats.2. The Grassland Butterfly Index has been adopted by the EU as a key measure of progress towards the target of halting biodiversity loss, restoring nature in agro-ecosystems and reversing the decline in pollinators by 2030, 1. Grassland is an important habitat for butterflies and many other pollinating insects. Over half of the 501 European butterflies use grasslands as one of their main habitats.2. The Grassland Butterfly Index has been adopted by the EU as a key measure of progress towards the target of halting biodiversity loss, restoring nature in agro-ecosystems and reversing the decline in pollinators by 2030,

Tumour-suppressive effect of oestrogen receptor β in colorectal cancer patients, colon cancer cells, and a zebrafish model

Oestrogen receptor β (ERβ) has been suggested to have anti-proliferative and anti-tumour effects in breast and prostate cancer cells, but other studies have indicated its tumour-promoting effects. Understanding the complex effects of this receptor in different contexts requires further study. We reported that high ERβ expression is independently associated with improved prognosis in female colorec

Efficacy of the antibacterial envelope to prevent cardiac implantable electronic device infection in a high-risk population

AimsInfection is a serious complication of cardiac implantable electronic device (CIED) therapy. An antibiotic-eluting absorbable envelope has been developed to reduce the infection rate, but studies investigating the efficacy and a reasonable number needed to treat in high-risk populations for infections are limited.Methods and resultsOne hundred and forty-four patients undergoing CIED implantati

Biomass burning emissions and influence of combustion variables in the cone-calorimeter

Emissions from biomass burning are highly variable and depend on combustion conditions as well as fuel properties. Simultaneous emissions from pyrolysis, smouldering, and combustion of the biomass material(s) burning leads to uncertainties in how these processes contribute to emissions of individual or groups of compounds as well as to total particle emissions. These uncertainties are difficult to

Phenotypic plasticity in floral scent in response to nutrient, but not water, availability in the perennial plant Arabis alpina

Floral scent is an important mediator of plant–pollinator interactions. Multiple recent studies report ample intraspecific scent variation among populations and individuals. Yet, few studies have eastimated effects of phenotypic plasticity on floral scent in response to differing environmental factors. In this study, we investigated the effects of nutrient and water availability on floral scent in

Protease Inhibitors or NNRTIs as First-Line HIV-1 Treatment in West Africa (PIONA) : A Randomized Controlled Trial

BACKGROUND: Nonnucleoside reverse transcriptase inhibitors (NNRTIs) are recommended as part of first-line treatment for HIV-1 in Africa. However, NNRTI-based regimens are more prone to resistance development than protease inhibitors (PIs) in a context in which drug interruptions are frequent. The aim of this study was to compare the efficacy and tolerability of NNRTIs with PIs in HIV-1-infected pa

Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database

Objectives To determine the causes and predictors of mortality in systemic sclerosis (SSc). Methods Patients with SSc (n=5860) fulfilling the American College of Rheumatology criteria and prospectively followed in the EULAR Scleroderma Trials and Research (EUSTAR) cohort were analysed. EUSTAR centres completed a structured questionnaire on cause of death and comorbidities. Kaplan-Meier and Cox pro

Diabetes Antibody Standardization Program: evaluation of assays for insulin autoantibodies

Aims/hypothesis Insulin autoantibodies (IAA) are important in type I diabetes risk assessment. However, their determination varies more between laboratories than other diabetes autoantibodies. The Diabetes Antibody Standardization Program (DASP) aims to improve and standardise measurement of autoantibodies associated with type I diabetes. We report the results of measurement of IAA from DASP works

90Yttrium-Ibritumomab-Tiuxetan as First-Line Treatment for Follicular Lymphoma: 30 Months of Follow-Up Data From an International Multicenter Phase II Clinical Trial.

PURPOSEWe report on a multicenter phase II trial of (90)yttrium-ibritumomab-tiuxetan ((90)YIT) as first-line stand-alone therapy for patients with follicular lymphoma (FL). PATIENTS AND METHODSFifty-nine patients with CD20(+) FL grade 1 to 3a in stages II, III, or IV, age 50 years old or older requiring therapy were enrolled. They received (90)YIT according to standard procedure. If complete respo

Analysis of genome plasticity in pathogenic and commensal Escherichia coli isolates by use of DNA arrays

Genomes of prokaryotes differ significantly in size and DNA composition. Escherichia coli is considered a model organism to analyze the processes involved in bacterial genome evolution, as the species comprises numerous pathogenic and commensal variants. Pathogenic and nonpathogenic E. coli strains differ in the presence and absence of additional DNA elements contributing to specific virulence tra

The activity of an insectivorous bat Neoromicia nana on tracks in logged and unlogged forest in tropical Africa

Logging activities and the associated creation of roads and tracks can disturb and fragment forests, which may lead to a loss of forest-dependent species and possibly favour nonforest generalists and edge species. The effects of such disturbance are poorly known for African insectivorous bats. We studied the activity patterns of insectivorous bats in a tropical African forest at Kibale National Pa

The draft genome of whitefly Bemisia tabaci MEAM1, a global crop pest, provides novel insights into virus transmission, host adaptation, and insecticide resistance

Background: The whitefly Bemisia tabaci (Hemiptera: Aleyrodidae) is among the 100 worst invasive species in the world. As one of the most important crop pests and virus vectors, B. tabaci causes substantial crop losses and poses a serious threat to global food security. Results: We report the 615-Mb high-quality genome sequence of B. tabaci Middle East-Asia Minor 1 (MEAM1), the first genome sequen

Treatment for neovascular age-related macular degeneration in Sweden : outcomes at seven years in the Swedish Macula Register

PURPOSE: To present Swedish Macula Register (SMR) data regarding treatment of neovascular age-related macular degeneration (AMD) in clinical practice since 2008.METHODS: A retrospective register-based study was conducted. Evaluation of baseline demographics, visual outcome and number of injections during this period is presented.RESULTS: Mean age at diagnosis was 79 ± (SD) 8 years; 65% were female

Wind-dependent foraging flight in the Osprey Pandion haliaetus

We studied the foraging technique of Ospreys Pandion haliaetus during different wind speed conditions at Lake Hammarsjon, Sweden in autumn 2003. Different fishing techniques were used with a shift in relation to wind speed: (1) without hovering, (2) hovering with pure flapping flight, (3) hovering with flapping flight and gliding into the wind, and (4) hovering with pure gliding. The results suppo

An analysis of subject areas and country participation for all health-related projects in the EU's FP5 and FP6 programmes

BACKGROUND: Previous analyses concerning health components of European Union (EU)-funded research have shown low project participation levels of the 12 newest member states (EU-12). Additionally, there has been a lack of subject-area analysis. In the Health Research for Europe project, we screened all projects of the EU's Framework Programmes for research FP5 and FP6 (1998-2006) to identify health

När äganderätten möter hänsynen till miljön - En studie av ersättningsrätten vid omprövning av vattenverksamhet

Framställningens övergripande syfte är att analysera huruvida en utmönstring av rätten till ersättning vid omprövning av vattenverksamhet, i enlighet med Vattenverksamhetsutredningens förslag, är förenligt med egendomsskyddet i Europakonventionen. Huvudregeln i svensk rätt är att den enskilde är berättigad till ersättning om det allmänna, genom en sådan inskränkning som avses i 2 kap. 15 § RF, åsThis thesis aims to analyze whether a discarding of compensation in the review of water operations, in accordance with the Water Operations Committee's proposal, is consistent with the protection of property of the ECHR (European Convention on Human Rights). The principal rule in Swedish law is that the individual is entitled to compensation when the government, through a restriction referred

Dynamic Pricing in Transport: a study on social and personal implications to travellers

Dynamic pricing is a pricing strategy where prices are no longer fixed or constant. Instead, they are continuously readjusted according to perceived demand and factors that influence the desirability of the product. It is in passenger transport where it has one of its biggest applications, in order to increase profits and maximize the use of limited capacity. While extensively studied for its econ