Sökresultat

Background. Primary glomerular disease (PGD) is a major cause of end-stage kidney disease (ESKD) leading to kidney replacement therapy (KRT). We aimed to describe incidence (trends) in individuals starting KRT for ESKD due to PGD and to examine their survival and causes of death. Methods. We used data from the European Renal Association (ERA) Registry on 69 854 patients who started KRT for ESKD du

HIV infection affects the course of tuberculosis (TB), and HIV and Mycobacterium tuberculosis (Mtb) synergize in disease progression through complex immunological interplay. To gain further understanding of these mechanisms, we compared the microRNA (miRNA) and small nucleolar RNA (snoRNA) expression patterns in whole blood of individuals with active TB, with and without HIV coinfection (HIV+/TB+

Popular Abstract in Swedish Alla kemikalier vi använder oss av och utsätter oss för påverkar både oss och den omvärld vi lever i. Under hela sin livscykel har de en påverkan på miljön, från de att man utvinner råmaterialen, när de tillverkas och när vi använder dem. Till och med efter att vi använt dem har kemikalierna en påverkan på miljön. Det gäller både schampot som följer med duschvattnet ut It is of at most importance that society reduces its impact on the environment. In the chemical industry the use of renewable resources will play a fundamental role in the transition to more sustainable chemical products. Also industrial biotechnology, i.e. the use of enzymes to convert raw material into valuable chemicals at low temperatures, leads to more sustainable processes. The research pres

The effect of reaction parameters on lipase-mediated chemo-enzymatic epoxidation of linoleic acid was investigated. Hydrogen peroxide was found to have the most significant effect on the reaction rate and degree of epoxidation. Excess of hydrogen peroxide with respect to the amount of double bonds was necessary in order to yield total conversion within a short time period, as well as at temperatur

Heart failure is a major concern to health care providers in Sweden due to its increasing prevalence and the rising health care costs. Heart failure affects more than 160000 Swedes, approximately 2% of the population. The costs for the management of heart failure have been calculated to be approximately SEK 2.500 million (Euro 275 million) which is 2% of the total health care budget. Most heart fa

The progenitor of the Dekkera/Brettanomyces clade separated from the Saccharomyces/Kluyveromyces clade over 200 million years ago. However, within both clades, several lineages developed similar physiological traits. Both Saccharomyces cerevisiae and Dekkera bruxellensis are facultative anaerobes; in the presence of excess oxygen and sugars, they accumulate ethanol (Crabtree effect) and they both

Objectives: To examine the effects of thiopurine exposure during pregnancy on intrahepatic cholestasis of pregnancy (ICP) in systemic lupus erythematosus (SLE) and inflammatory bowel disease (IBD) pregnancies using nationwide data from Swedish healthcare registers. Methods: This register-based cohort study included all singleton pregnancies with prevalent SLE or IBD in Sweden, 2007-2022. Exposure

Patients with von Willebrand disease (VWD) and haemophilia A (HA) lack, to varying degrees, the von Willebrand factor (VWF) and coagulation factor VIII (FVIII) that are critical for normal haemostasis. These conditions in turn make patients prone to uncontrolled bleeding. Historically, patients with severe forms of VWD or HA were crippled before adulthood and their life expectancy was significantl

Popular Abstract in Swedish Energianvändningen i världen måste minska drastiskt inom en snar framtid för att därmed minska utsläppen av växthusgaser och bromsa klimatförändringarna. Energi och handlande med energikällor har även blivit nationella säkerhetsfrågor. Inom Europeiska Unionen används ungefär 40% av den totala energianvändningen i byggnader, vilket innebär ungefär 36% av det totala koldiThe use of energy is a major global issue both according to climate changes but also in the aspect of national safety tied to the trade with energy sources. Of the total energy use in the member states of the European Union, about 40% is used in residential and commercial buildings. Passive houses are one way to reduce the energy use in buildings and at the same time keep a good indoor comfort. Th

PURPOSE: To present a new perimetric index for calculating the rate of glaucomatous progression and to compare its performance with the traditional mean deviation index (MDI). DESIGN: Experimental study describing a device and retrospective cohort study. METHODS: We developed a new visual field index, the glaucoma progression index (GPI), intended to be less affected by cataract than the MDI by ca

Popular Abstract in Swedish Den dansk-svenske forfatter Gustaf Munch-Petersen (1912-1938) betragtes som en af portalskikkelserne i den danske lyriske modernisme. Han døde 26 år gammel som frivillig i den spanske borgerkrig, en konflikt, vi i dag ofte betragter som en del af optakten til anden verdenskrig. Dette tidlige endeligt gjorde ham til en af skandinavisk litteraturs ”unge døde”. Men det er The Danish-Swedish writer Gustaf Munch-Petersen (1912-1938) is considered one of the pioneers of Danish modernist poetry. His death at the age of 26 as a volunteer in the Spanish Civil War, a conflict that was later widely understood as a prelude to the Second World War, made him one of “the young dead” of Scandinavian literature. But this is only one among several pictures of him. Self and identi

The development of inhibitory antibodies to factor (F) VIII and FIX continues to be a major challenge in the treatment of patients with hemophilia. In patients with low-responding inhibitors, it is usually possible to saturate the inhibitor with the deficient factor and to achieve hemostasis, but in patients with high-responding inhibitors, two major tasks have to be considered. One is how to trea

Five molybdenum oxide samples, subjected to conditions of oxidative ammonolysis and ammoxidation of toluene at 450 and 460°C, respectively, have been characterized using X-ray diffraction, scanning and transmission electron microscopy, and specific surface area measurements. In oxidative ammonolysis, the relatively large, freshly prepared MoO3 crystals are reduced to smaller MoO2 crystals with a c

In the present study we investigate the fate of citalopram (CIT) at neutral pH using advanced water treatment technologies that include O(3), ClO(2) oxidation, UV irradiation and Fenton oxidation. The ozonation resulted in 80% reduction after 30min treatment. Oxidation with ClO(2) removed>90% CIT at a dosage of 0.1mgL(-1). During UV irradiation 85% reduction was achieved after 5min, while Fenton w

Previous studies have indicated that ionizing radiation, particularly during childhood, is the main established risk factor for thyroid cancer. History of benign nodules/adenoma, goiter, iodine deficiency or high-iodine intake might be other associated factors. We wanted to define the histology-specific thyroid cancer risk in the first-generation immigrants to Sweden. We used the 2010 update of th

Chemical abundances for 15 elements (C, N, O, Na, Mg, Al, Si, K, Ca, Ti, V, Cr, Mn, Fe, and Ni) are presented for 83 stellar members of the 4 Gyr old solar-metallicity open cluster M67. The sample contains stars spanning a wide range of evolutionary phases, from G dwarfs to red clump stars. The abundances were derived from near-IR (λ1.5-1.7 μm) high-resolution spectra (R ,F= ,F22,500) from the SD

MASTER (MAnaging Speeds of Traffic on European Roads) aims to provide recommendations for speed management strategies and policies and to elaborate guidelines for the development of innovative speed management tools. Within the framework of the project, field trials with a car equipped with a speed limiter were carried out in three “regional typical” European countries: Sweden, the Netherlands, an

When writing computer software one is often forced to balance the need for high run-time performance with high programmer productivity. By using a high-level language it is often possible to cut development times, but this typically comes at the cost of reduced run-time performance. Using a lower-level language, programs can be made very efficient but at the cost of increased development time. Re

OBJECTIVES: To determine whether endometrial volume or power Doppler indices as measured by three-dimensional (3D) ultrasound imaging can discriminate between benign and malignant endometrium, to compare their diagnostic performance with that of endometrial thickness measurement using two-dimensional (2D) ultrasound examination, and to determine whether power Doppler indices add any diagnostic inf

Congenic DRF.(f/f) rats are protected from type 1 diabetes (T1D) by 34 Mb of F344 DNA introgressed proximal to the Gimap5 lymphopenia gene. To dissect the genetic factor(s) that confer protection from T1D in the DRF.(f/f) rat line, DRF.(f/f) rats were crossed to inbred BBDR or DR.(lyp/lyp) rats to generate congenic sublines that were genotyped, monitored for T1D and positional candidate genes sequ