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Exploring the Potential to Improve Photodynamic Therapy of Skin Cancer by Exogenous Catalase and m-ALA Delivery Using a Crystalip® Topical Cream Formulation

Förbättring av Krämer för Fotodynamisk Behandling av Hudcancer Fotodynamisk terapi (PDT) är en modern och relativt skonsam behandlingsmetod som används vid vissa typer av hudcancer och förstadier till hudcancer. I stället för att operera bort vävnad används ett ljuskänsligt läkemedel som appliceras på huden. När det behandlade området belyses med ljus av en specifik våglängd reagerar läkemedlet mePhotodynamic therapy (PDT) is an established treatment for actinic keratosis and selected non-melanoma skin cancers. Still, its broader use is limited by pain, skin irritation, and formulation constraints associated with high photosensitiser concentrations. This study aimed to develop and evaluate a Crystalip®-based topical PDT formulation that enables two-step manufacturing, delivers methyl-amino

Copy number variants in the kallikrein gene cluster.

The kallikrein gene family (KLK1-KLK15) is the largest contiguous group of protease genes within the human genome and is associated with both risk and outcome of cancer and other diseases. We searched for copy number variants in all KLK genes using quantitative PCR analysis and analysis of inheritance patterns of single nucleotide polymorphisms. Two deletions were identified: one 2235-bp deletion

Treatment of Popliteal Aneurysm by Open and Endovascular Surgery: A Contemporary Study of 592 Procedures in Sweden

WHAT THIS STUDY ADDS Previous comparisons between open and endovascular repair of popliteal aneurysms have focused on asymptomatic patients, and have short follow up. This study is strengthened by the fact that it is contemporary, population based, without any selection bias, reporting on all kinds of presentations, and has approximately 90% 1 year follow up data. It shows that endovascular repair

Population genomics in a disease targeted primary cell model

The common genetic variants associated with complex traits typically lie in noncoding DNA and may alter gene regulation in a cell type-specific manner. Consequently, the choice of tissue or cell model in the dissection of disease associations is important. We carried out an expression quantitative trait loci (eQTL) study of primary human osteoblasts (HOb) derived from 95 unrelated donors of Swedis

Endogenous substrates utilized by rat brain in severe insulin-induced hypoglycemia

Several previous studies have demonstrated that severe hypoglycemia is accompanied by consumption of endogenous brain substrates (glycolytic and citric acid cycle metabolites and free amino acids) and some have shown a loss of structural components as well, notably phospholipids. In the present study, on paralysed and artificially ventilated rats, we measured cerebral oxygen and glucose consumptio

Smooth terminating bands in Te-112: Particle-hole induced collectivity

The Gammasphere spectrometer, in conjunction with the Microball charged-particle array, was used to investigate high-spin states in Te-112 via Ni-58(Ni-58, 4p gamma) reactions at 240 and 250 MeV. Several smooth terminating bands were established, and lifetime measurements were performed for the strongest one using the Doppler-shift attenuation method. Results obtained in the spin range 18-32h yiel

Icelandic Collembola. Revised checklist and general comments.

The last survey of Icelandic Collembola is that of Olafsson (1991) reporting 77 species and 26 taxa of infraspecific level (forms, varieties and aberrations of which some are good species, others not). The Study of Icelandic soil fauna has intensified over the last decades, mainly in the fields of applied sciences (agriculture, forestry). However, few works report Collembola down to species level

Thermal models of buildings : determination of temperatures, heating and cooling loads : theories, models and computer programs

The need to estimate indoor temperatures, heating or cooling load and energy requirements for buildings arises in many stages of a buildings life cycle, e.g. at the early layout stage, during the design of a building and for energy retrofitting planning. Other purposes are to meat the authorities requirements given in building codes. All these situations require good calculation methods. The main

Human3.6M: Large Scale Datasets and Predictive Methods for 3D Human Sensing in Natural Environments.

We introduce a new dataset, Human3.6M, of 3.6 Million 3D Human poses, acquired by recording the performance of 11 subjects, under 4 different viewpoints, for training realistic human sensing systems and for evaluating the next generation of human pose estimation models. Besides increasing the size the current state of the art datasets by several orders of magnitude, we aim to complement such datas

Measurement of the production of a W boson in association with a charm quark in pp collisions at root s=7 TeV with the ATLAS detector

The production of a W boson in association with a single charm quark is studied using 4.6 fb(-1) of pp collision data at root s = 7 TeV collected with the ATLAS detector at the Large Hadron Collider. In events in which a W boson decays to an electron or muon, the charm quark is tagged either by its semileptonic decay to a muon or by the presence of a charmed meson. The integrated and differential

Numerical analysis of ballistic imaging for revealing liquid breakup in dense sprays

This work demonstrates the capacity of a ballistic imaging instrument to suppress diffuse photons and improve image contrast, making it possible to view fluid structure in a spray where a fog of droplets occludes the near field. Analysis of the system is performed by means of a numerical system model. The model simulates light propagation and scattering in the measurement volume using a Monte Carl

Identification of a trypsin-like serine protease from Trichoderma reesei QM9414

In the present work the genetically modified Trichoderma reesei strain QM9414 was used to produce full-length Ce17B (endoglucanase I, EGI) under the control of the constitutive Aspergillus nidulans gpdA promoter in the presence of glucose. However, the full-length Ce17B enzyme was found to be truncated to lower molecular weight components in the culture broth. Truncation of recombinant proteins pr

Captured metagenomics: large-scale targeting of genes based on 'sequence capture' reveals functional diversity in soils.

Microbial enzyme diversity is a key to understand many ecosystem processes. Whole metagenome sequencing (WMG) obtains information on functional genes, but it is costly and inefficient due to large amount of sequencing that is required. In this study, we have applied a captured metagenomics technique for functional genes in soil microorganisms, as an alternative to WMG. Large-scale targeting of fun

Risk of thyroid cancer in relatives of patients with medullary thyroid carcinoma by age at diagnosis

The familial risk of medullary thyroid carcinoma (MTC alone or as part of multiple endocrine neoplasms, MEN2A/MEN2B) is high, so we aimed to answer open questions about the lifetime cumulative risk of thyroid cancer (LCRTC at 0-79 years) among relatives of MTC patients by age and sex. For this nationwide study, a cohort of 3217 first-/second-degree relatives (FDRs/SDRs) of 389 MTC patients diagnos

Learning Online Multi-sensor Depth Fusion

Many hand-held or mixed reality devices are used with a single sensor for 3D reconstruction, although they often comprise multiple sensors. Multi-sensor depth fusion is able to substantially improve the robustness and accuracy of 3D reconstruction methods, but existing techniques are not robust enough to handle sensors which operate with diverse value ranges as well as noise and outlier statistics

E2 cec synthesis 05

Review papers (including abstracts) identified in the Web of Science database on August 29 and 30, 2018, applying the following categories in the search (see Table 5.1): (LaU OR LaC OR FoC) AND BpE AND ClV AND (ObD OR MoD) AND NoP (in alphabetical order) Bagley, J. E., et al. (2015). "Biophysical impacts of climate-smart agriculture in the Midwest United States." Plant Cell and Environment 38(9):

https://www.cec.lu.se/sites/cec.lu.se/files/2020-11/e2_cec_synthesis_05.pdf - 2026-05-23

EUPRERA Annual Congress 2025

EUPRERA Annual Congress 2025 24-27 September EUPRERA ANNUAL CONGRESS At the Intersection between Academia and Practice in Public Relations and Strategic Communication ABOUT THE EUPRERA ANNUAL CONGRESS The European Public Relations Education and Research Association (EUPRERA) is an autonomous organisation with over 550 members across 50 countries, with a vision of advancing academic research and kn

https://www.isk.lu.se/en/sites/isk.lu.se.en/files/2025-01/EUPRERA%20Annual%20Congress%202025.pdf - 2026-05-23

LPED 2020 3

Centre for Economic Demography Lund University School of Economics and Management P.O. Box 7083 SE-220 07 Lund, Sweden www.ed.lu/publications/Lund-Papers-in-Economic-Demography/ Gendered Parenthood in the 21st Century? Everyday Time Use and Stress in Sweden, 2000/01-2010/11 MARIA STANFORS LUND PAPERS IN ECONOMIC DEMOGRAPHY 2020:3 Gendered Parenthood in the 21st century? Everyday Time Use and Stres

https://www.lusem.lu.se/sites/lusem.lu.se/files/2024-07/LPED_2020_3.pdf - 2026-05-23

Statement Of Purpose 2025-26 IMBM LUSEM

Master’s programme in International Marketing and Brand Management – Statement of purpose, year 2024/2025 1/42023-10-16 Master’s programme in International Marketing and Brand Management STATEMENT OF PURPOSE | YEAR 2025/2026 The statement of purpose is one of the most important, and challenging, elements of your application. It is your opportunity to stand out from the hundreds of other ap- plican

https://www.lusem.lu.se/sites/lusem.lu.se/files/2024-10/Statement%20of%20purpose%202025-26%20IMBM%20LUSEM.pdf - 2026-05-23