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Cancer follow-up supported by patient-reported outcomes in patients undergoing intended curative complex surgery for advanced cancer

Background and aim: Patient activation (PA) and Patient Involvement (PI) are considered elements in good survivorship. We aimed to evaluate the effect of a follow-up supported by electronic patient-reported outcomes (ePRO) on PA and PI. Method: From February 2017 to January 2019, we conducted an explorative interventional study. We included 187 patients followed after intended curative complex sur

Impact of Left Ventricular Morphology on Adverse Outcomes Following Stage 1 Palliation for Hypoplastic Left Heart Syndrome : 20 Years of National Data From Sweden

BackgroundHypoplastic left heart syndrome is associated with significant morbidity and mortality. We aimed to assess the influence of left ventricular morphology and choice of shunt on adverse outcome in patients with hypoplastic left heart syndrome and stage 1 palliation.Methods and ResultsThis was a retrospective analysis of patients with hypoplastic left heart syndrome with stage 1 palliation b

Increasing global ecosystem respiration between 1982 and 2015 from Earth observation-based modelling

Aim: Earth observation-based estimates of land–atmosphere exchange of carbon are essential for understanding the response of the terrestrial biosphere to climatic change and other anthropogenic forcing. Temperature, soil water content and gross primary production are the main drivers of ecosystem respiration (Reco), and the main aims of this study are to develop an Reco model driven by long-term g

Exposome project for health and occupational research night shift cohort (EPHOR-NIGHT) : a unique resource to advance research on night shift work and chronic disease

Purpose The EPHOR-NIGHT cohort was established to investigate how night shift work influences biological pathways and chronic disease risk using a comprehensive working-life exposome approach, focusing on cardiometabolic, mental health, cognitive and biological ageing outcomes. Participant The cohort includes 937 workers aged 20–65 years (88%female), primarily from the healthcare sector (96%) in S

Activity of cefepime/enmetazobactam against highly multidrug-resistant bacterial isolates recovered from war-associated wounds in Ukraine

Background: Escalating resistance among Gram-negative pathogens limits β-lactam options. Cefepime/enmetazobactam combines a fourth-generation cephalosporin with a class A β-lactamase inhibitor. We evaluated its activity against multidrug, extensive and pandrug-resistant war-wound isolates from Ukraine.Materials and methods: We tested 215 clinical samples (2022-2023) isolated from wounded patients

A Wideband Small-Footprint Platform-Insensitive Monopolar Patch Based on Slot-Assisted High-Order Mode Tailoring

A wideband, compact monopolar patch antenna with an inherent filtering response is presented in this paper. By employing a slot-assisted mode-tailoring technique, the field distributions of several higher-order modes at the patch center are engineered to produce a stable monopolar radiation pattern with enhanced bandwidth. The closed-form analysis indicates that increasing the current intensity at

Interventions for negative symptoms in schizophrenia : efficacy and clinical interpretability in a meta-analysis of 451 randomized controlled trials

Negative symptoms (avolition, anhedonia, asociality, blunted affect, and alogia) are among the most disabling features of schizophrenia spectrum disorders. In the absence of treatment consensus guidelines, this PRISMA-compliant meta-analysis (PROSPERO: CRD42024613967) evaluated efficacy and clinical significance of interventions targeting this dimension. Web of Science/PsycInfo databases were sear

Changes in joint cartilage aggrecan after knee injury and in osteoarthritis

Objective. To determine the concentrations of aggrecan fragments in synovial fluid from patients with knee joint injury, osteoarthritis (OA), or acute pyrophosphate arthritis (PPA; pseudogout), and to test their relative reactivity with the 846 epitope, a putative marker of cartilage aggrecan synthesis. Methods. Samples of knee joint fluid from 385 patients and 9 healthy-knee volunteers were obtai

Longitudinal study of cognitive function in glioma patients treated with modern radiotherapy techniques and standard chemotherapy

Introduction: Cognitive function is an important outcome measure in patients with brain tumor, providing information about the patient’s clinical situation, treatment effects and possible progressive disease. The aim of this longitudinal study was to evaluate effects of the currently used radiation and chemotherapy treatment on cognitive function and to investigate associations between cognitive f

Inaccuracy of GFR predictions by plasma cystatin C in patients without kidney dysfunction and in advanced kidney disease.

BACKGROUND: In clinical practice there is need for a simple and reliable test for determination of impaired renal function. With reductions in GFR, the plasma cystatin C concentration (C, mg/l) will increase earlier than serum creatinine, and it is generally agreed that plasma cystatin C is only little affected by body weight, age or sex. However, some reports indicate that cystatin C may be influ

Prognostic value of lymphocyte-monocyte ratio at diagnosis in Hodgkin lymphoma : A meta-analysis

Background: Prognoses of most adult Hodgkin lymphoma (HL) patients are excellent; most of them can achieve permanent remission that can be considered cured. However, many are under-treated or over-treated by standard modern therapies. An accurate determination of prognosis may allow clinicians to design personalised treatment according to individual risk of disease progression and survival. Lympho

New Evidence for Selective Reporting in Climate Change Science

Populärvetenskaplig sammanfattning: Är klimatforskningen skev? En central fråga är om vi kan lita på att vetenskapliga tidskrifter återger en rättvis bild av aktuella forskningsresultat? Dessutom bör vi fråga oss hur rapporteringen påverkas då betydande händelser sker inom vetenskapsvärlden. I november 2007 och senare 2009 skedde två viktiga företeelser inom klimatforskningen som potentiellt kanAbstract The declaration of a scientific consensus concerning anthropogenic causes for climate change by the IPCC in their fourth assessment report (AR4), published in 2007, initiated a heated debate. During this debate, experts within the IPCC were accused of selective reporting and the AR4 got strong source criticism by politicians, stakeholders and climate skeptics in general. The debate furth

Evaluation of overheating risks and passive cooling measures in low energy Swedish dwellings

Overheating in buildings is becoming a major concern and cause for various health issues. Existing research and previous studies on the issue were examined to acquire relevant information about the definition of overheating, its possible causes, and the heath impacts it could have on human health. The review included data on the current status of thermal comfort and overheating regulations in Swed

Det som krävs för att Lunds Klimatallians ska kunna utveckla sina medlemmars hållbarhetsarbete

Lunds Klimatallians har ambitioner att hjälpa sina medlemmar arbeta mot en hållbar utveckling och letar efter nya metoder för att förbättra sin insats. Lunds Klimatallians är en organisation som startades i initiativ av Lund Kommuns miljöstrategiska enhet i syfte att bidra till Sveriges genomförande av FN:s klimatmål. Målen ska leda världen mot en hållbar utveckling men i dagsläget finns hållbarheLund's Climate Alliance was initiated 2010 by the municipality of Lund, in southern Sweden, to support local climate adaptation and mitigation efforts. The purpose of this paper is to investigate what each member of Lund's Climate Alliance believes will be necessary to realize sustainability goals particular to their organization in the future. The study thereby points to new topics, activ

Alignment and orientation of Nanowires in a thin film under the influence of an electric field

Produktion av en nanotrådssolcell För att ta itu med miljöpåverkan från växthusgaser krävs en övergång till förnyelsebara energikällor. Ett exempel på en sådan källa är nanotrådssolceller. I mitt examensarbete har jag undersökt hur nanotrådar kan arrangeras på sådant sätt som krävs för att kunna omvandla solljuset till elektricitet. Global uppvärmning är ett hot som till stor del orsakas av utslThe demand for cheaper and more efficient solar cells is high. One way to decrease cost of material, while maintaining a high degree of efficiency, is to take advantage of nanomaterials. A thin film containing pn-junction nanowires can convert light with an efficiency comparable to traditional planar cells, while using a fraction of the material, and thus reduce costs. At the company Sol Voltaics

Varumärkets olika ansikten. - Varumärkesskapande inom tre kontexter

Fallstudie: Swedbank Syfte: Syftet med denna uppsats är att undersöka hur ett varumärke kan framställas inom tre olika kontexter. Denna studie kommer att fokuseras kring aktörerna företag och konsument inom den interna företagsmiljön samt den fysiska och virtuella tjänstemiljön. Metod: Studien utgår från en etnografisk metod, där vi studerar och deltar i olika miljöer. För att erhålla datainsamlin

Severe, life-threatening, and fatal chronic health conditions after allogeneic blood or marrow transplantation in childhood

Background: A comprehensive assessment of morbidity after allogeneic bone marrow transplantation (BMT) performed in childhood remains understudied. Methods: Seven hundred eighty-nine allogeneic BMT recipients who had survived ≥2 years after BMT performed between 1974 and 2014 at age <22 years and 690 siblings completed a 255-item survey self-reporting sociodemographics and chronic health condition

Paleomagnetism, magnetic anisotropy and U-Pb baddeleyite geochronology of the early Neoproterozoic Blekinge-Dalarna dolerite dykes, Sweden

Paleogeographic proximity of Baltica and Laurentia in the supercontinent Rodinia has been widely accepted. However, robust paleomagnetic poles are still scarce, hampering quantitative tests of proposed relative positions of the two cratons. A recent paleomagnetic study of the early Neoproterozoic Blekinge-Dalarna dolerite (BDD) dykes in Sweden provided a 946–935 Ma key pole for Baltica, but earlie