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Observational Health Data Analysis of the Cardiovascular Adverse Events of Systemic Treatment in Patients with Metastatic Hormone-sensitive Prostate Cancer : Big Data Analytics Using the PIONEER Platform

Background and objective: Although cardiovascular toxicity from modern systemic treatments in metastatic hormone-sensitive prostate cancer (mHSPC) remains a concern, real-world data are limited. We aimed to characterise patients treated for mHSPC across multiple large cohorts and estimate cardiovascular adverse event (AE) risks. Methods: Leveraging PIONEER's Big Data platform, with databases stand

Symptoms and objective signs of peripheral sensory neuropathy in POTS and correlations to gastrointestinal symptoms

Aim Postural orthostatic tachycardia syndrome (POTS) is a disorder with cardiovascular autonomic dysfunction where multiple and variable symptoms are common, including those from the peripheral and enteric nervous systems. We aimed to investigate subjective and objective signs of small and large fiber neuropathy in a Swedish POTS cohort compared with healthy controls. Secondly, we wanted to examin

Alcohol Intake and Cardiovascular Outcomes in Patients With Atrial Fibrillation : RE-LY AF Registry Analysis

Background: Alcohol intake increases recurrence of atrial fibrillation (AF), but its relationship with cardiovascular outcomes is less well characterized. We aimed to study the association between different levels of alcohol intake and cardiovascular outcomes in a global cohort of patients with AF. Methods: This is a cross-sectional analysis of the RE-LY AF registry, including 15,400 patients with

High one-year mortality following intensive care among adults with influenza A(H1N1)pdm09, A(H3N2), or B in Southern Sweden : a retrospective observational study

Background: Influenza ranges from a mild and self-limiting infection to a life-threatening disease with high mortality despite intensive care. Conclusive data on the association between influenza type/subtype and mortality among adults treated at intensive care units (ICU) is lacking. Objectives: To investigate the mortality in adults admitted to ICU with laboratory-confirmed influenza during thre

A High Rate of Acute Injuries in Para Alpine Skiing—A Combined Prospective Study of Injuries Reported at the Sochi 2014, PyeongChang 2018, and Beijing 2022 Paralympic Winter Games

Para Alpine skiing is one of the largest sports at the Paralympic Winter Games. Recent studies report high injury rates in this sport. However, limited evidence exists regarding sport-specific injury characteristics, which is essential for targeted prevention. The aim of this study was to describe the overall incidence proportion and incidence of injuries reported by athletes participating in Alpi

Exposome project for health and occupational research night shift cohort (EPHOR-NIGHT) : a unique resource to advance research on night shift work and chronic disease

Purpose The EPHOR-NIGHT cohort was established to investigate how night shift work influences biological pathways and chronic disease risk using a comprehensive working-life exposome approach, focusing on cardiometabolic, mental health, cognitive and biological ageing outcomes. Participant The cohort includes 937 workers aged 20–65 years (88%female), primarily from the healthcare sector (96%) in S

Activity of cefepime/enmetazobactam against highly multidrug-resistant bacterial isolates recovered from war-associated wounds in Ukraine

Background: Escalating resistance among Gram-negative pathogens limits β-lactam options. Cefepime/enmetazobactam combines a fourth-generation cephalosporin with a class A β-lactamase inhibitor. We evaluated its activity against multidrug, extensive and pandrug-resistant war-wound isolates from Ukraine.Materials and methods: We tested 215 clinical samples (2022-2023) isolated from wounded patients

A Wideband Small-Footprint Platform-Insensitive Monopolar Patch Based on Slot-Assisted High-Order Mode Tailoring

A wideband, compact monopolar patch antenna with an inherent filtering response is presented in this paper. By employing a slot-assisted mode-tailoring technique, the field distributions of several higher-order modes at the patch center are engineered to produce a stable monopolar radiation pattern with enhanced bandwidth. The closed-form analysis indicates that increasing the current intensity at

Qmod 2019 sep. preliminar program 2

4th September 2013, Wednesday QMOD 2019 Preliminary Program 13th October, Sunday 16:00-18:00 QMOD-ICQSS Registration 18:00-19:00 Welcome Reception 19:00-21:00 Welcome Dinner 14th October, Monday 08:30-09:00 Conference Opening Su Mi Dahlgaard, Park & Jens J. Dahlgaard Conference Co-Chairs 09:00-10:00 Plenary Session 1 Heejun Park, Professor, Korea Platfornovation: Platform-based Innovation 10:00-10

https://www.ses.lu.se/en/sites/ses.lu.se.en/files/qmod_2019_sep._preliminar_program_2.pdf - 2026-05-09

Changes in joint cartilage aggrecan after knee injury and in osteoarthritis

Objective. To determine the concentrations of aggrecan fragments in synovial fluid from patients with knee joint injury, osteoarthritis (OA), or acute pyrophosphate arthritis (PPA; pseudogout), and to test their relative reactivity with the 846 epitope, a putative marker of cartilage aggrecan synthesis. Methods. Samples of knee joint fluid from 385 patients and 9 healthy-knee volunteers were obtai

Two phase ii randomized trials on the CRTh2 antagonist AZD1981 in adults with asthma

Background: Chemoattractant receptor-homologous molecule expressed on T helper type 2 (Th2) cell (CRTh2) receptor antagonists is being investigated for asthma. Objectives: The aim of this study was to assess the effects of the CRTh2 receptor antagonist, AZD1981 (with/without inhaled corticosteroids [ICSs]), on lung function and asthma control. Patients and methods: Adults aged 18–60 years were enr

Hållbara energilösningar på framtida Jägersro Hästcenter -dimensionering av solcellssystem och batterilager

Nuvarande Jägersro trav- och galoppbana i sydöstra Malmö ska bytas ut mot bostäder. Skånska Travsällskapet planerar bygga nya Jägersro Hästcenter på sin privata mark precis bredvid. De önskar att hästcentret blir Europas ledande med fokus på hållbarhet. I juli 2024 planeras den första byggnaden invigas, den avsedd för publik, som antas tecknas till ett effektabonnemang. Det förutspås att lokal eThe current Jägersro horse racetrack in southeast Malmö will be replaced with apartments. Alongside this area Skånska Travsällskapet plans to build a new Jägersro Horse Center on their private land. They wish the center to be Europe's most prominent with a focus on sustainability. In July 2024, the first building is planned to be inaugurated, which is assumed to be subscribed for a power ratin

Det som krävs för att Lunds Klimatallians ska kunna utveckla sina medlemmars hållbarhetsarbete

Lunds Klimatallians har ambitioner att hjälpa sina medlemmar arbeta mot en hållbar utveckling och letar efter nya metoder för att förbättra sin insats. Lunds Klimatallians är en organisation som startades i initiativ av Lund Kommuns miljöstrategiska enhet i syfte att bidra till Sveriges genomförande av FN:s klimatmål. Målen ska leda världen mot en hållbar utveckling men i dagsläget finns hållbarheLund's Climate Alliance was initiated 2010 by the municipality of Lund, in southern Sweden, to support local climate adaptation and mitigation efforts. The purpose of this paper is to investigate what each member of Lund's Climate Alliance believes will be necessary to realize sustainability goals particular to their organization in the future. The study thereby points to new topics, activ

Evaluation of overheating risks and passive cooling measures in low energy Swedish dwellings

Overheating in buildings is becoming a major concern and cause for various health issues. Existing research and previous studies on the issue were examined to acquire relevant information about the definition of overheating, its possible causes, and the heath impacts it could have on human health. The review included data on the current status of thermal comfort and overheating regulations in Swed

Alignment and orientation of Nanowires in a thin film under the influence of an electric field

Produktion av en nanotrådssolcell För att ta itu med miljöpåverkan från växthusgaser krävs en övergång till förnyelsebara energikällor. Ett exempel på en sådan källa är nanotrådssolceller. I mitt examensarbete har jag undersökt hur nanotrådar kan arrangeras på sådant sätt som krävs för att kunna omvandla solljuset till elektricitet. Global uppvärmning är ett hot som till stor del orsakas av utslThe demand for cheaper and more efficient solar cells is high. One way to decrease cost of material, while maintaining a high degree of efficiency, is to take advantage of nanomaterials. A thin film containing pn-junction nanowires can convert light with an efficiency comparable to traditional planar cells, while using a fraction of the material, and thus reduce costs. At the company Sol Voltaics

New Evidence for Selective Reporting in Climate Change Science

Populärvetenskaplig sammanfattning: Är klimatforskningen skev? En central fråga är om vi kan lita på att vetenskapliga tidskrifter återger en rättvis bild av aktuella forskningsresultat? Dessutom bör vi fråga oss hur rapporteringen påverkas då betydande händelser sker inom vetenskapsvärlden. I november 2007 och senare 2009 skedde två viktiga företeelser inom klimatforskningen som potentiellt kanAbstract The declaration of a scientific consensus concerning anthropogenic causes for climate change by the IPCC in their fourth assessment report (AR4), published in 2007, initiated a heated debate. During this debate, experts within the IPCC were accused of selective reporting and the AR4 got strong source criticism by politicians, stakeholders and climate skeptics in general. The debate furth

Direct hollow fiber liquid phase membrane extraction and LC-MS/MS determination of non-steroidal anti-inflammatory drugs in fish

Popular summary The fate of non-steroidal anti-inflammatory drugs The knowledge about distribution of drugs between sewage sludge, water phases and water living organisms is vital for predictions of the fate and transport routes of toxic substances to the environment. And the distribution of drugs in the environment can be used as a base for risk assessments and it also can be used to define desir

Kan allmän plats tas i anspråk utan ersättning?

Fram till 1 januari 2015 hade länsstyrelsen möjlighet att besluta om ”113-förordnande” enligt 6 kap. 5 § PBL. 113-förordnandet innebar att kommunen kunde ta mark i anspråk utan ersättning om det ansågs skäligt med hänsyn till den nytta som exploatören förväntades få av planens genomförande och till omständigheterna i övrigt. Hur mark för allmän plats ska värderas och ersättas regleras i 4 kap. 3a Until 1st of January 2015, the county administrative board could decide on “113-regulation” according to Ch. 6 Art. 5 Planning and Building Act. The regulation meant that the municipality could claim land for public spaces without compensation if it was fair considering the benefit expected to be achieved by the planer's implementation and the circumstances in general. How public space is to b

Cangrelor During Percutaneous Coronary Intervention in Patients With Cardiogenic Shock or Cardiac Arrest

Background: Little is known regarding treatment with cangrelor during percutaneous coronary intervention (PCI) in patients with myocardial infarction complicated by cardiogenic shock or cardiac arrest. Objectives: The aim of this study was to investigate the effects of such cangrelor treatment during PCI in patients with myocardial infarction complicated by cardiogenic shock or cardiac arrest. Met

Cardiac rehabilitation and physical activity decrease the risk of stroke after acute myocardial infarction : A nationwide cohort study in Sweden

Background: Stroke and acute myocardial infarction (AMI) rank among the leading causes of mortality. Physical activity and exercise are recommended as part of rehabilitation after AMI to prevent cardiovascular events, but the importance for stroke prevention has not been investigated using population-based data. Objectives: To determine associations between participation in exercise-based cardiac